2023
Nelson, PT., Lee, EB., Cykowski, MD., Alafuzoff, I., Arfanakis, K., Attems, J., Brayne, C., Corrada, MM., Dugger, BN., Flanagan, ME., Ghetti, B., Grinberg, LT., Grossman, M., Grothe, MJ., Halliday, GM., Hasegawa, M., Hokkanen, SRK., Hunter, S., Jellinger, K., Kawas, CH., Keene, CD., Kouri, N., Kovacs, GG., Leverenz, JB., Latimer, CS., Mackenzie, IR., Mao, Q., McAleese, KE., Merrick, R., Montine, TJ., Murray, ME., Myllykangas, L., Nag, S., Neltner, JH., Newell, KL., Rissman, RA., Saito, Y., Sajjadi, SA., Schwetye, KE., Teich, AF., Thal, DR., Tomé, SO., Troncoso, JC., Wang, S-HJ., White, CL., Wisniewski, T., Yang, H-S., Schneider, JA., Dickson, DW. and Neumann, M., 2023. LATE-NC staging in routine neuropathologic diagnosis: an update. Acta Neuropathol, v. 145
Doi: http://doi.org/10.1007/s00401-022-02524-2
Nichols, E., Merrick, R., Hay, SI., Himali, D., Himali, JJ., Hunter, S., Keage, HAD., Latimer, CS., Scott, MR., Steinmetz, JD., Walker, JM., Wharton, SB., Wiedner, CD., Crane, PK., Keene, CD., Launer, LJ., Matthews, FE., Schneider, J., Seshadri, S., White, L., Brayne, C. and Vos, T., 2023. The prevalence, correlation, and co-occurrence of neuropathology in old age: harmonisation of 12 measures across six community-based autopsy studies of dementia. Lancet Healthy Longev, v. 4
Doi: http://doi.org/10.1016/S2666-7568(23)00019-3
2022
Nelson, PT., Brayne, C., Flanagan, ME., Abner, EL., Agrawal, S., Attems, J., Castellani, RJ., Corrada, MM., Cykowski, MD., Di, J., Dickson, DW., Dugger, BN., Ervin, JF., Fleming, J., Graff-Radford, J., Grinberg, LT., Hokkanen, SRK., Hunter, S., Kapasi, A., Kawas, CH., Keage, HAD., Keene, CD., Kero, M., Knopman, DS., Kouri, N., Kovacs, GG., Labuzan, SA., Larson, EB., Latimer, CS., Leite, REP., Matchett, BJ., Matthews, FE., Merrick, R., Montine, TJ., Murray, ME., Myllykangas, L., Nag, S., Nelson, RS., Neltner, JH., Nguyen, AT., Petersen, RC., Polvikoski, T., Reichard, RR., Rodriguez, RD., Suemoto, CK., Wang, S-HJ., Wharton, SB., White, L. and Schneider, JA., 2022. Frequency of LATE neuropathologic change across the spectrum of Alzheimer's disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts. Acta Neuropathol, v. 144
Doi: http://doi.org/10.1007/s00401-022-02444-1
2021
Wallace, L., Hunter, S., Theou, O., Fleming, J., Rockwood, K. and Brayne, C., 2021. Frailty and neuropathology in relation to dementia status: the Cambridge City over-75s Cohort study. Int Psychogeriatr,
Doi: http://doi.org/10.1017/S1041610220003932
2020
Wang, H., Lee, C., Hunter, S., Fleming, J., Brayne, C. and CC75C Study Collaboration, , 2020. Longitudinal analysis of the impact of loneliness on cognitive function over a 20-year follow-up. Aging Ment Health, v. 24
Doi: http://doi.org/10.1080/13607863.2019.1655704
Hokkanen, SRK., Kero, M., Kaivola, K., Hunter, S., Keage, HAD., Kiviharju, A., Raunio, A., Tienari, PJ., Paetau, A., Matthews, FE., Fleming, J., Graff, C., Polvikoski, TM., Myllykangas, L., Brayne, C. and EClipSE Collaboration, , 2020. Putative risk alleles for LATE-NC with hippocampal sclerosis in population-representative autopsy cohorts. Brain Pathol, v. 30
Doi: http://doi.org/10.1111/bpa.12773
Hunter, S., Hokkanen, SRK., Keage, HAD., Fleming, J., Minett, T., Polvikoski, T., Allinson, K. and Brayne, C., 2020. TDP-43 Related Neuropathologies and Phosphorylation State: Associations with Age and Clinical Dementia in the Cambridge City over-75s Cohort Journal of Alzheimer's Disease,
Doi: http://doi.org/10.3233/jad-191093
2019 (Accepted for publication)
Nelson, P., Dickson, D., Trokanowski, J., Jack, CJ., Boyle, P., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Chui, H., Coyle-Gilchrist, I., Fardo, D., Flanagan, M., Halliday, G., Hokkanen, S., Hunter, S., Jicha, G., Katsumata, Y., Kawas, C., Keene, C., Kovacs, G., Kukull, W., Levey, A., Makkinejad, N., Montine, T., Murayama, S., Murray, M., Nag, S., Rissman, R., Seeley, W., Sperling, R., White, C., Yu, L. and Schneider, J., 2019 (Accepted for publication). Limbic-predominant Age-related TDP-43 Encephalopathy (LATE): Consensus Working Group Report Brain,
Doi: http://doi.org/10.1093/brain/awz099
2019
Nelson, PT., Dickson, DW., Trojanowski, JQ., Jack, CR., Boyle, PA., Arfanakis, K., Rademakers, R., Alafuzoff, I., Attems, J., Brayne, C., Coyle-Gilchrist, ITS., Fardo, DW., Flanagan, ME., Halliday, G., Hunter, S., Jicha, GA., Katsumata, Y., Kawas, CH., Keene, CD., Kovacs, GG., Kukull, WA., Levey, AI., Makkinejad, N., Montine, TJ., Murray, ME., Nag, S., Seeley, WW., Sperling, RA., White, CL. and Schneider, JA., 2019. Reply: LATE to the PART-y. Brain, v. 142
Doi: http://doi.org/10.1093/brain/awz226
2018 (Accepted for publication)
Hunter, S., Smailagic, N. and Brayne, CEG., 2018 (Accepted for publication). Aβ and the dementia syndrome: simple versus complex perspectives. European Journal of Clinical Investigation,
2018
Smailagic, N., Hunter, S., Lafortune, L. and Brayne, CEG., 2018. Do CSF biomarkers and FDG PET imaging show sufficient clinical utility for diagnosis of dementia subtypes? BMJ: British Medical Journal, v. 361
Doi: http://doi.org/10.1136/bmj.k2438
Nascimento, C., Di Lorenzo Alho, AT., Bazan Conceição Amaral, C., Leite, REP., Nitrini, R., Jacob-Filho, W., Pasqualucci, CA., Hokkanen, SRK., Hunter, S., Keage, H., Kovacs, GG., Grinberg, LT. and Suemoto, CK., 2018. Prevalence of transactive response DNA-binding protein 43 (TDP-43) proteinopathy in cognitively normal older adults: systematic review and meta-analysis. Neuropathol Appl Neurobiol, v. 44
Doi: http://doi.org/10.1111/nan.12430
2017 (Accepted for publication)
Hunter, SE., Smailagic, N. and Brayne, C., 2017 (Accepted for publication). Dementia research: populations, progress, problems and predictions Journal of Alzheimer's Disease,
Hokkanen, SRK., Hunter, S., Polvikoski, TM., Keage, HAD., Minett, T., Matthews, FE. and Brayne, C., 2017 (Accepted for publication). Hippocampal sclerosis, hippocampal neuron loss patterns and Tdp-43 in the aged population Brain Pathology,
Doi: http://doi.org/10.1111/bpa.12556
Hunter, SE. and Brayne, C., 2017 (Accepted for publication). Understanding the roles of mutations in the amyloid precursor protein in Alzheimer disease Molecular Psychiatry,
Doi: 10.1038/mp.2017.218
2017
Hunter, S. and Brayne, C., 2017. Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research? J Negat Results Biomed, v. 16
Doi: 10.1186/s12952-017-0066-3
Hunter, S. and Brayne, C., 2017. Erratum to: Do anti-amyloid beta protein antibody cross reactivities confound Alzheimer disease research? J Negat Results Biomed, v. 16
Doi: http://doi.org/10.1186/s12952-017-0073-4
Fleming, J., Brayne, C., Calloway, R., Perrels, A., Farquhar, M., Barclay, S. and CC75C Cambridge City over-75s Cohort, , 2017. Dying comfortably in very old age with or without dementia in different care settings – a representative "older old" population study BMC Geriatrics, v. 17
Doi: http://doi.org/10.1186/s12877-017-0605-2
2016
Hunter, S., Martin, S. and Brayne, C., 2016. The APP Proteolytic System and Its Interactions with Dynamic Networks in Alzheimer's Disease. Methods Mol Biol, v. 1303
Doi: 10.1007/978-1-4939-2627-5_3
Fleming, J., Farquhar, M., Brayne, C. and Barclay, S., 2016. Death and the Oldest Old: Attitudes and Preferences for End-of-Life Care - Qualitative Research within a Population-Based Cohort Study PLOS ONE, v. 11
Doi: http://doi.org/10.1371/journal.pone.0150686
Le Couteur, DG., Hunter, S. and Brayne, C., 2016. Solanezumab and the amyloid hypothesis for Alzheimer's disease. BMJ, v. 355
2015
Hunter, S., Minett, T., Polvikoski, T., Mukaetova-Ladinska, E., Brayne, C. and Cambridge City over-75s Cohort Collaboration, , 2015. Re-examining tau-immunoreactive pathology in the population: granulovacuolar degeneration and neurofibrillary tangles. Alzheimers Res Ther, v. 7
Doi: 10.1186/s13195-015-0141-2
2014
Hunter, S. and Brayne, C., 2014. Integrating the molecular and the population approaches to dementia research to help guide the future development of appropriate therapeutics Biochemical Pharmacology, v. 88
Doi: http://doi.org/10.1016/j.bcp.2013.12.015
Keage, HAD., Hunter, S., Matthews, FE., Ince, PG., Hodges, J., Hokkanen, S., Highley, JR., Dening, T. and Brayne, C., 2014. TDP-43 in the Population: Prevalence and Associations with Dementia and Age. J Alzheimers Dis,
Doi: http://doi.org/10.3233/JAD-132351
D'Alton, S., Hunter, S., Whitehouse, P., Brayne, C. and George, D., 2014. Adapting to dementia in society: a challenge for our lifetimes and a charge for public health. J Alzheimers Dis, v. 42
Doi: http://doi.org/10.3233/JAD-140213
Keage, HAD., Hunter, S., Matthews, FE., Ince, PG., Hodges, J., Hokkanen, SRK., Highley, JR., Dening, T. and Brayne, C., 2014. TDP-43 pathology in the population: prevalence and associations with dementia and age. J Alzheimers Dis, v. 42
Doi: http://doi.org/10.3233/JAD-132351
Hunter, S. and Brayne, C., 2014. Integrating the molecular and the population approaches to dementia research to help guide the future development of appropriate therapeutics. Biochem Pharmacol, v. 88
Doi: http://doi.org/10.1016/j.bcp.2013.12.015
2013
Hunter, S., Arendt, T. and Brayne, C., 2013. The senescence hypothesis of disease progression in alzheimer disease: An Integrated matrix of disease pathways for FAD and SAD Molecular Neurobiology, v. 48
Doi: http://doi.org/10.1007/s12035-013-8445-3
Hunter, S., Arendt, T. and Brayne, C., 2013. The senescence hypothesis of disease progression in Alzheimer disease: an integrated matrix of disease pathways for FAD and SAD. Mol Neurobiol, v. 48
Doi: http://doi.org/10.1007/s12035-013-8445-3
2012
Stephan, BCM., Matthews, FE., Hunter, S., Savva, GM., Bond, J., McKeith, IG., Ince, P., Brayne, C. and Medical Research Council Cognitive Function and Ageing Study (MRC CFAS), , 2012. Neuropathological profile of mild cognitive impairment from a population perspective. Alzheimer Dis Assoc Disord, v. 26
Doi: http://doi.org/10.1097/WAD.0b013e31822fc24d
Stephan, BCM., Hunter, S., Harris, D., Llewellyn, DJ., Siervo, M., Matthews, FE. and Brayne, C., 2012. The neuropathological profile of mild cognitive impairment (MCI): a systematic review. Mol Psychiatry, v. 17
Doi: 10.1038/mp.2011.147
Stephan, BCM., Matthews, FE., Ma, B., Muniz, G., Hunter, S., Davis, D., McKeith, IG., Foster, G., Ince, PG. and Brayne, C., 2012. Alzheimer and vascular neuropathological changes associated with different cognitive States in a non-demented sample. J Alzheimers Dis, v. 29
Doi: http://doi.org/10.3233/JAD-2011-110518
Richardson, K., Hunter, S., Dening, T., Xuereb, JH., Matthews, FE., Brayne, C., Fleming, J. and Cambridge City over-75s Cohort (CC75C) Study Neuropathology Collaboration, , 2012. Neuropathological correlates of falling in the CC75C population-based sample of the older old. Curr Alzheimer Res, v. 9
Doi: 10.2174/156720512801322636
Hunter, S. and Brayne, C., 2012. Relationships between the amyloid precursor protein and its various proteolytic fragments and neuronal systems. Alzheimers Res Ther, v. 4
Doi: 10.1186/alzrt108
Stephan, BCM., Hunter, S., Harris, D., Llewellyn, DJ., Siervo, M., Matthews, FE. and Brayne, C., 2012. The neuropathological profile of mild cognitive impairment (MCI): A systematic review Molecular Psychiatry, v. 17
Doi: http://doi.org/10.1038/mp.2011.147
2011
Stephan, BCM., Matthews, FE., Hunter, S., Savva, GM., Bond, J., McKeith, IG., Ince, P. and Brayne, C., 2011. Neuropathological profile of mild cognitive impairment from a population perspective Alzheimer Disease & Associated Disorders,
2010
Hunter, S., Friedland, RP. and Brayne, C., 2010. Time for a change in the research paradigm for Alzheimer's disease: the value of a chaotic matrix modeling approach. CNS Neurosci Ther, v. 16
Doi: http://doi.org/10.1111/j.1755-5949.2009.00117.x
2009
Brayne, C., Richardson, K., Matthews, FE., Fleming, J., Hunter, S., Xuereb, JH., Paykel, E., Mukaetova-Ladinska, EB., Huppert, FA., O'Sullivan, A., Dening, T. and Cambridge City Over-75s Cohort Cc75c Study Neuropathology Collaboration, , 2009. Neuropathological correlates of dementia in over-80-year-old brain donors from the population-based Cambridge city over-75s cohort (CC75C) study. J Alzheimers Dis, v. 18
Doi: 10.3233/JAD-2009-1182
