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Research summary: Immuno-epidemiology of schistosomiasis

Publications from Elements

Datasets

2022 (No publication date)

  • Oettle, RC., Dickinson, HA., Fitzsimmons, CM., Sacko, M., Tukahebwa, EM. and Wilson, S., 2022 (No publication date). Research data supporting Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like protein expression in Schistosoma haematobium and Schistosoma mansoni infection
  • Journal articles

    2022

  • Asuming-Brempong, EK., Ayi, I., van der Puije, W., Gyan, BA., Larbi, IA., Ashong, Y., Frempong, NA., Quartey, JK., Otchere, J., Jones, FM., Wilson, S., Dunne, DW. and Boakye, DA., 2022. Increased ShTAL1 IgE responses post-Praziquantel treatment may be associated with a reduced risk to re-infection in a Ghanaian S. haematobium-endemic community. PLoS Negl Trop Dis, v. 16
    Doi: http://doi.org/10.1371/journal.pntd.0010115
  • 2021

  • Mawa, PA., Kincaid-Smith, J., Tukahebwa, EM., Webster, JP. and Wilson, S., 2021. Schistosomiasis Morbidity Hotspots: Roles of the Human Host, the Parasite and Their Interface in the Development of Severe Morbidity. Front Immunol, v. 12
    Doi: http://doi.org/10.3389/fimmu.2021.635869
  • Gasan, TA., Kuipers, ME., Roberts, GH., Padalino, G., Forde-Thomas, JE., Wilson, S., Wawrzyniak, J., Tukahebwa, EM., Hoffmann, KF. and Chalmers, IW., 2021. Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae. PLoS Negl Trop Dis, v. 15
    Doi: http://doi.org/10.1371/journal.pntd.0009981
  • 2020 (Reported date)

  • Crosnier, C., Hokke, CH., Protasio, AV., Brandt, C., Rinaldi, G., Langenberg, MCC., Clare, S., Janse, JJ., Wilson, S., Berriman, M., Roestenberg, M. and Wright, GJ., 2020 (Reported date). Screening of a Library of Recombinant Schistosoma mansoni Proteins With Sera From Murine and Human Controlled Infections Identifies Early Serological Markers The Journal of Infectious Diseases, v. jiaa329
    Doi: http://doi.org/10.1093/infdis/jiaa329
  • 2020

  • Wangwiwatsin, A., Protasio, AV., Wilson, S., Owusu, C., Holroyd, NE., Sanders, MJ., Keane, J., Doenhoff, MJ., Rinaldi, G. and Berriman, M., 2020. Transcriptome of the parasitic flatworm Schistosoma mansoni during intra-mammalian development PLoS neglected tropical diseases, v. 14
    Doi: http://doi.org/10.1371/journal.pntd.0007743
  • 2019

  • Angelo, T., Kinung’hi, SM., Buza, J., Mwanga, JR., Kariuki, HC. and Wilson, S., 2019. Community knowledge, perceptions and water contact practices associated with transmission of urinary schistosomiasis in an endemic region: a qualitative cross-sectional study BMC Public Health, v. 19
    Doi: http://doi.org/10.1186/s12889-019-7041-5
  • 2018

  • Angelo, T., Buza, J., Kinung'hi, SM., Kariuki, HC., Mwanga, JR., Munisi, DZ. and Wilson, S., 2018. Geographical and behavioral risks associated with Schistosoma haematobium infection in an area of complex transmission. Parasit Vectors, v. 11
    Doi: http://doi.org/10.1186/s13071-018-3064-5
  • Egesa, M., Lubyayi, L., Jones, FM., van Diepen, A., Chalmers, IW., Tukahebwa, EM., Bagaya, BS., Hokke, CH., Hoffmann, KF., Dunne, DW., Elliott, AM., Yazdanbakhsh, M., Wilson, S. and Cose, S., 2018. Antibody responses to Schistosoma mansoni schistosomula antigens. Parasite Immunol, v. 40
    Doi: http://doi.org/10.1111/pim.12591
  • Egesa, M., Lubyayi, L., Tukahebwa, EM., Bagaya, BS., Chalmers, IW., Wilson, S., Hokke, CH., Hoffmann, KF., Dunne, DW., Yazdanbakhsh, M., Labuda, LA. and Cose, S., 2018. Schistosoma mansoni schistosomula antigens induce Th1/Pro-inflammatory cytokine responses. Parasite Immunol, v. 40
    Doi: http://doi.org/10.1111/pim.12592
  • 2017

  • Stecher, CW., Sacko, M., Madsen, H., Wilson, S., Wejse, C., Keita, AD., Landouré, A., Traoré, MS., Kallestrup, P., Petersen, E. and Vennervald, B., 2017. Anemia and growth retardation associated with Schistosoma haematobium infection in Mali: a possible subtle impact of a neglected tropical disease. Trans R Soc Trop Med Hyg, v. 111
    Doi: http://doi.org/10.1093/trstmh/trx037
  • Oettle, R. and Wilson, S., 2017. The Interdependence between Schistosome Transmission and Protective Immunity Tropical Medicine and Infectious Disease, v. 2
    Doi: http://doi.org/10.3390/tropicalmed2030042
  • Kildemoes, AO., Vennervald, BJ., Tukahebwa, EM., Kabatereine, NB., Magnussen, P., de Dood, CJ., Deelder, AM., Wilson, S. and van Dam, GJ., 2017. Rapid clearance of Schistosoma mansoni circulating cathodic antigen after treatment shown by urine strip tests in a Ugandan fishing community - Relevance for monitoring treatment efficacy and re-infection. PLoS Negl Trop Dis, v. 11
    Doi: http://doi.org/10.1371/journal.pntd.0006054
  • Stecher, CW., Fofana, HKM., Madsen, H., Wilson, S., Keita, AD., Landouré, A., Traoré, MS., Vennervald, BJ., Reimert, CM. and Sacko, M., 2017. Inflammation dynamics after praziquantel treatment of Schistosoma haematobium reflected by urinary eosinophil cationic protein. Trans R Soc Trop Med Hyg, v. 111
    Doi: http://doi.org/10.1093/trstmh/trx057
  • Stecher, CW., Madsen, H., Wilson, S., Sacko, M., Wejse, C., Keita, AD., Landouré, A., Traoré, MS., Kallestrup, P., Petersen, E. and Vennervald, B., 2017. Organomegaly in Mali before and after praziquantel treatment. A possible association with Schistosoma haematobium. Heliyon, v. 3
    Doi: http://doi.org/10.1016/j.heliyon.2017.e00440
  • 2016

  • Tweyongyere, R., Namanya, H., Naniima, P., Cose, S., Tukahebwa, EM., Elliott, AM., Dunne, DW. and Wilson, S., 2016. Human eosinophils modulate peripheral blood mononuclear cell response to Schistosoma mansoni adult worm antigen in vitro. Parasite Immunology, v. 38
    Doi: http://doi.org/10.1111/pim.12336
  • Wilson, S., 2016. Disgusting parasites? Nat Microbiol, v. 1
    Doi: http://doi.org/10.1038/nmicrobiol.2016.90
  • 2015

  • Castelino, JM., Routledge, MN., Wilson, S., Dunne, DW., Mwatha, JK., Gachuhi, K., Wild, CP. and Gong, YY., 2015. Aflatoxin exposure is inversely associated with IGF1 and IGFBP3 levels in vitro and in Kenyan schoolchildren. Mol Nutr Food Res, v. 59
    Doi: http://doi.org/10.1002/mnfr.201300619
  • Kildemoes, AO., Vennervald, BJ., Kabatereine, NB., Tukahebwa, EM., Magnussen, P., Wilson, S., de Dood, CJ., Deelder, AM. and van Dam, GJ., 2015. Rapid clearance of schistosomal circulating cathodic antigen (CCA) after treatment shown by urine strip tests - importance for monitoring treatment efficacy and re-infection TROPICAL MEDICINE & INTERNATIONAL HEALTH, v. 20
  • 2014

  • Wilson, S., Jones, FM., van Dam, GJ., Corstjens, PLAM., Riveau, G., Fitzsimmons, CM., Sacko, M., Vennervald, BJ. and Dunne, DW., 2014. Human Schistosoma haematobium antifecundity immunity is dependent on transmission intensity and associated with immunoglobulin G1 to worm-derived antigens. J Infect Dis, v. 210
    Doi: http://doi.org/10.1093/infdis/jiu374
  • Wilson, S. and Dunne, DW., 2014. A pressing need for parasite immunologists to contribute to our understanding of human-neglected tropical diseases. Parasite Immunol, v. 36
    Doi: http://doi.org/10.1111/pim.12136
  • Mazigo, HD., Dunne, DW., Wilson, S., Kinung'hi, SM., Pinot de Moira, A., Jones, FM., Morona, D. and Nuwaha, F., 2014. Co-infection with Schistosoma mansoni and Human Immunodeficiency Virus-1 (HIV-1) among residents of fishing villages of north-western Tanzania. Parasit Vectors, v. 7
    Doi: http://doi.org/10.1186/s13071-014-0587-2
  • Wilson, S., Jones, FM., Kenty, L-C., Mwatha, JK., Kimani, G., Kariuki, HC. and Dunne, DW., 2014. Posttreatment changes in cytokines induced by Schistosoma mansoni egg and worm antigens: dissociation of immunity- and morbidity-associated type 2 responses. J Infect Dis, v. 209
    Doi: http://doi.org/10.1093/infdis/jit826
  • Pinot de Moira, A., Fitzsimmons, CM., Jones, FM., Wilson, S., Cahen, P., Tukahebwa, E., Mpairwe, H., Mwatha, JK., Bethony, JM., Skov, PS., Kabatereine, NB. and Dunne, DW., 2014. Suppression of basophil histamine release and other IgE-dependent responses in childhood Schistosoma mansoni/hookworm coinfection. J Infect Dis, v. 210
    Doi: http://doi.org/10.1093/infdis/jiu234
  • 2013

  • Pinot de Moira, A., Jones, FM., Wilson, S., Tukahebwa, E., Fitzsimmons, CM., Mwatha, JK., Bethony, JM., Kabatereine, NB. and Dunne, DW., 2013. Effects of treatment on IgE responses against parasite allergen-like proteins and immunity to reinfection in childhood schistosome and hookworm coinfections. Infect Immun, v. 81
    Doi: http://doi.org/10.1128/IAI.00748-12
  • Wilson, S., Jones, FM., Fofana, HKM., Landouré, A., Kimani, G., Mwatha, JK., Sacko, M., Vennervald, BJ. and Dunne, DW., 2013. A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils. Parasite Immunol, v. 35
    Doi: http://doi.org/10.1111/pim.12035
  • Wilson, S., Jones, FM., Fofana, HKM., Doucouré, A., Landouré, A., Kimani, G., Mwatha, JK., Sacko, M., Vennervald, BJ. and Dunne, DW., 2013. Rapidly boosted Plasma IL-5 induced by treatment of human Schistosomiasis haematobium is dependent on antigen dose, IgE and eosinophils. PLoS Negl Trop Dis, v. 7
    Doi: http://doi.org/10.1371/journal.pntd.0002149
  • Tukahebwa, EM., Magnussen, P., Madsen, H., Kabatereine, NB., Nuwaha, F., Wilson, S. and Vennervald, BJ., 2013. A Very High Infection Intensity of Schistosoma mansoni in a Ugandan Lake Victoria Fishing Community Is Required for Association with Highly Prevalent Organ Related Morbidity PLoS Neglected Tropical Diseases, v. 7
    Doi: http://doi.org/10.1371/journal.pntd.0002268
  • Mazigo, HD., Nuwaha, F., Wilson, S., Kinung'hi, SM., Morona, D., Waihenya, R., Heukelbach, J. and Dunne, DW., 2013. Epidemiology and interactions of Human Immunodeficiency Virus – 1 and Schistosoma mansoni in sub-Saharan Africa Infectious Diseases of Poverty, v. 2
    Doi: http://doi.org/10.1186/2049-9957-2-2
  • Koukounari, A., Donnelly, CA., Moustaki, I., Tukahebwa, EM., Kabatereine, NB., Wilson, S., Webster, JP., Deelder, AM., Vennervald, BJ. and van Dam, GJ., 2013. A latent Markov modelling approach to the evaluation of circulating cathodic antigen strips for schistosomiasis diagnosis pre- and post-praziquantel treatment in Uganda. PLoS Comput Biol, v. 9
    Doi: http://doi.org/10.1371/journal.pcbi.1003402
  • 2012

  • Wilson, S. and Dunne, DW., 2012. Advances in our understanding of the epidemiology of Plasmodium and schistosome infection: informing coinfection studies. Curr Opin HIV AIDS, v. 7
    Doi: http://doi.org/10.1097/COH.0b013e328351b9fb
  • Fitzsimmons, CM., Jones, FM., Stearn, A., Chalmers, IW., Hoffmann, KF., Wawrzyniak, J., Wilson, S., Kabatereine, NB. and Dunne, DW., 2012. The Schistosoma mansoni tegumental-allergen-like (TAL) protein family: influence of developmental expression on human IgE responses. PLoS Negl Trop Dis, v. 6
    Doi: http://doi.org/10.1371/journal.pntd.0001593
  • Wilson, S. and Dunne, DW., 2012. Advances in our understanding of the epidemiology of Plasmodium and schistosome infection: Informing coinfection studies Current Opinion in HIV and AIDS, v. 7
    Doi: http://doi.org/10.1097/COH.0b013e328351b9fb
  • Gong, YY., Wilson, S., Mwatha, JK., Routledge, MN., Castelino, JM., Zhao, B., Kimani, G., Curtis Kariuki, H., Vennervald, BJ., Dunne, DW. and Wild, CP., 2012. Aflatoxin exposure may contribute to chronic hepatomegaly in Kenyan school children Environmental Health Perspectives, v. 120
    Doi: http://doi.org/10.1289/ehp.1104357
  • Mazigo, HD., Nuwaha, F., Kinung'hi, SM., Morona, D., Pinot de Moira, A., Wilson, S., Heukelbach, J. and Dunne, DW., 2012. Epidemiology and control of human schistosomiasis in Tanzania. Parasit Vectors, v. 5
    Doi: http://doi.org/10.1186/1756-3305-5-274
  • 2011

  • Wilson, S., Vennervald, BJ. and Dunne, DW., 2011. Chronic hepatosplenomegaly in African school children: a common but neglected morbidity associated with schistosomiasis and malaria. PLoS Negl Trop Dis, v. 5
    Doi: http://doi.org/10.1371/journal.pntd.0001149
  • 2010

  • Yiannakoulias, N., Wilson, S., Kariuki, HC., Mwatha, JK., Ouma, JH., Muchiri, E., Kimani, G., Vennervald, BJ. and Dunne, DW., 2010. Locating irregularly shaped clusters of infection intensity GEOSPATIAL HEALTH, v. 4
  • Wilson, S., Vennervald, BJ., Kadzo, H., Ireri, E., Amaganga, C., Booth, M., Kariuki, HC., Mwatha, JK., Kimani, G., Ouma, JH., Muchiri, E. and Dunne, DW., 2010. Health implications of chronic hepatosplenomegaly in Kenyan school-aged children chronically exposed to malarial infections and Schistosoma mansoni. Trans R Soc Trop Med Hyg, v. 104
    Doi: http://doi.org/10.1016/j.trstmh.2009.08.006
  • 2009

  • Wilson, S., Jones, FM., Mwatha, JK., Kimani, G., Booth, M., Kariuki, HC., Vennervald, BJ., Ouma, JH., Muchiri, E. and Dunne, DW., 2009. Hepatosplenomegaly associated with chronic malaria exposure: evidence for a pro-inflammatory mechanism exacerbated by schistosomiasis. Parasite Immunol, v. 31
    Doi: http://doi.org/10.1111/j.1365-3024.2008.01078.x
  • 2008

  • Wilson, S., Jones, FM., Mwatha, JK., Kimani, G., Booth, M., Kariuki, HC., Vennervald, BJ., Ouma, JH., Muchiri, E. and Dunne, DW., 2008. Hepatosplenomegaly is associated with low regulatory and Th2 responses to schistosome antigens in childhood schistosomiasis and malaria coinfection. Infect Immun, v. 76
    Doi: http://doi.org/10.1128/IAI.01433-07
  • 2007

  • Wilson, S., Booth, M., Jones, FM., Mwatha, JK., Kimani, G., Kariuki, HC., Vennervald, BJ., Ouma, JH., Muchiri, E. and Dunne, DW., 2007. Age-adjusted Plasmodium falciparum antibody levels in school-aged children are a stable marker of microgeographical variations in exposure to Plasmodium infection. BMC Infect Dis, v. 7
    Doi: http://doi.org/10.1186/1471-2334-7-67
  • Wilson, S., Vennervald, BJ., Kadzo, H., Ireri, E., Amaganga, C., Booth, M., Kariuki, HC., Mwatha, JK., Kimani, G., Ouma, JH., Muchiri, E. and Dunne, DW., 2007. Hepatosplenomegaly in Kenyan schoolchildren: exacerbation by concurrent chronic exposure to malaria and Schistosoma mansoni infection. Trop Med Int Health, v. 12
    Doi: http://doi.org/10.1111/j.1365-3156.2007.01950.x
  • 2006

  • Pierrot, C., Wilson, S., Lallet, H., Lafitte, S., Jones, FM., Daher, W., Capron, M., Dunne, DW. and Khalife, J., 2006. Identification of a novel antigen of Schistosoma mansoni shared with Plasmodium falciparum and evaluation of different cross-reactive antibody subclasses induced by human schistosomiasis and malaria INFECT IMMUN, v. 74
    Doi: http://doi.org/10.1128/IAI.01724-05
  • 2005

  • Wilson, S., Booth, M., Vennervald, BJ., Jones, FM., Kariuki, HC., Amaganga, C., Kadzo, H., Ireri, E., Mwatha, JK., Kimani, G., Ouma, JH., Muchiri, E. and Dunne, DW., 2005. Schistosoma mansoni exacerbates hepatosplenomegaly in an area of mesoendemic malaria transmission AM J TROP MED HYG, v. 73
  • 2004

  • White, JK., Stewart, A., Popoff, J-F., Wilson, S. and Blackwell, JM., 2004. Incomplete glycosylation and defective intracellular targeting of mutant solute carrier family 11 member 1 (Slc11a1). Biochem J, v. 382
    Doi: http://doi.org/10.1042/BJ20040808
  • Theses / dissertations

    2021 (No publication date)

  • Oettle, R., 2021 (No publication date). Human antibody-mediated immunity against infection and parasite fecundity in Schistosoma mansoni and Schistosoma haematobium infection
  • Book chapters

    2012

  • Wilson, S. and Khalife, J., 2012. Malaria and Schistosomes
    Doi: http://doi.org/10.1002/9781118393321.ch22
  • Conference proceedings

    2008

  • Wilson, S., Vennervald, BJ., Kabatereine, NB., Sacko, M., Kimani, G., Muchiri, E. and Dunne, DW., 2008. COMPARISON OF POTENTIALLY PROTECTIVE HUMAN TH2 RESPONSES AGAINST DIFFERENT SCHISTOSOME SPECIES AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, v. 79