2019 (Accepted for publication)
Traylor, M., Anderson, C., Rutten-Jacobs, L., Falcone, G., Comeau, M., Ay, H., Sudlow, C., Xu, H., Mitchell, B., Cole, J., Rexrode, K., Jimenez-Conde, J., Schmidt, R., Grewal, R., Sacco, R., Ribases, M., Rundek, T., Rosand, J., Dichgans, M., Lee, J-M., Langefeld, C., Kittner, S., Markus, H., Woo, D. and Malik, R., 2019 (Accepted for publication). The Subtype Specificity of Genetic Loci Associated with Stroke in 16,664 cases and 32,792 controls Circulation: Genomic and Precision Medicine,
2019
Badran, A., Hollocks, MJ., Brookes, RL., Morris, RG. and Markus, HS., 2019. Framingham vascular age is associated with worse cognitive performance in the middle-aged and elderly. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn, v. 26
Doi: http://doi.org/10.1080/13825585.2018.1499866
Rutten, JW., Van Eijsden, BJ., Duering, M., Jouvent, E., Opherk, C., Pantoni, L., Federico, A., Dichgans, M., Markus, HS., Chabriat, H. and Lesnik Oberstein, SAJ., 2019. The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant. Genet Med, v. 21
Doi: http://doi.org/10.1038/s41436-018-0088-3
Debette, S., Schilling, S., Duperron, M-G., Larsson, SC. and Markus, HS., 2019. Clinical Significance of Magnetic Resonance Imaging Markers of Vascular Brain Injury: A Systematic Review and Meta-analysis. JAMA Neurology, v. 76
Doi: http://doi.org/10.1001/jamaneurol.2018.3122
Drazyk, AM., Tan, RYY., Tay, J., Traylor, M., Das, T. and Markus, HS., 2019. Encephalopathy in a Large Cohort of British Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Patients. Stroke,
Doi: http://doi.org/10.1161/STROKEAHA.118.023661
van Leijsen, EMC., Tay, J., van Uden, IWM., Kooijmans, ECM., Bergkamp, MI., van der Holst, HM., Ghafoorian, M., Platel, B., Norris, DG., Kessels, RPC., Markus, HS., Tuladhar, AM. and de Leeuw, F-E., 2019. Memory decline in elderly with cerebral small vessel disease explained by temporal interactions between white matter hyperintensities and hippocampal atrophy. Hippocampus, v. 29
Doi: http://doi.org/10.1002/hipo.23039
Sweeney, MD., Montagne, A., Sagare, AP., Nation, DA., Schneider, LS., Chui, HC., Harrington, MG., Pa, J., Law, M., Wang, DJJ., Jacobs, RE., Doubal, FN., Ramirez, J., Black, SE., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, PM., Markus, HS., Al-Shahi Salman, R., Allan, SM., Quinn, TJ., Kalaria, RN., Werring, DJ., Carare, RO., Touyz, RM., Williams, SCR., Moskowitz, MA., Katusic, ZS., Lutz, SE., Lazarov, O., Minshall, RD., Rehman, J., Davis, TP., Wellington, CL., González, HM., Yuan, C., Lockhart, SN., Hughes, TM., Chen, CLH., Sachdev, P., O'Brien, JT., Skoog, I., Pantoni, L., Gustafson, DR., Biessels, GJ., Wallin, A., Smith, EE., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, MMB., Román, GC., Hamel, E., Seshadri, S., Gottesman, RF., van Buchem, MA., Arvanitakis, Z., Schneider, JA., Drewes, LR., Hachinski, V., Finch, CE., Toga, AW., Wardlaw, JM. and Zlokovic, BV., 2019. Vascular dysfunction-The disregarded partner of Alzheimer's disease. Alzheimers Dement, v. 15
Doi: http://doi.org/10.1016/j.jalz.2018.07.222
2018 (Accepted for publication)
Tay, J., Tuladhar, AM., Hollocks, MJ., Brookes, RL., Tozer, DJ., Barrick, TR., Husain, M., de Leeuw, F-E. and Markus, HS., 2018 (Accepted for publication). Apathy is associated with large-scale white matter network disruption in small vessel disease Neurology,
Lawrence, A., Tozer, DJ., Stamatakis, E. and Markus, H., 2018 (Accepted for publication). A comparison of functional and tractography based networks in cerebral small vessel disease NeuroImage: Clinical,
Tozer, DJ., Zeestraten, E., Lawrence, AJ., Barrick, T. and Markus, HS., 2018 (Accepted for publication). Texture Analysis of T1 weighted and fluid attenuated inversion recovery images detects abnormalities which correlate with disease progression in small vessel disease Stroke, v. 49
Doi: http://doi.org/10.1161/STROKEAHA.117.019970
Lisiecka, DM., Tozer, D., Morris, RG., Lawrence, AJ., Barrick, TR. and Markus, HS., 2018 (Accepted for publication). Involvement of the reward network is associated with apathy in cerebral small vessel disease Journal of Affective Disorders,
Traylor, MS., 2018 (Accepted for publication). Genetic variation in PLEKHG1 is associated with white matter hyperintensities (N=11,226) Neurology,
Markus, HS., Lawrence, A., Zeestraten, E., Benjamin, P., Lambert, C., Morris, R. and Barrick, T., 2018 (Accepted for publication). Longitudinal decline in structural networks predicts dementia in cerebral small vessel disease Neurology,
Larsson, SC., Traylor, M., Mishra, A., Howson, JMM., Michaëlsson, K. and Markus, HS., 2018 (Accepted for publication). Serum 25-Hydroxyvitamin D Concentrations and Ischemic Stroke and its Subtypes: A Mendelian Randomization Study Stroke,
Traylor, MS. and Markus, H., 2018 (Accepted for publication). Causal Impact of Type 2 Diabetes on Cerebral Small Vessel Disease: A Mendelian Randomization Analysis Stroke,
Rutten-Jacobs, L., Tozer, DJ., During, M., Malik, R., Dichgans, M., Markus, H. and Traylor, M., 2018 (Accepted for publication). Genetic study of white matter integrity in UK Biobank (N=8,448) and the overlap with stroke, depression and dementia Stroke,
Traylor, MS., 2018 (Accepted for publication). Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: followup study of 306,473 UK Biobank participants British Medical Journal,
Traylor, MS. and Markus, H., 2018 (Accepted for publication). Genetic association study of white matter integrity in 8,448 UK Biobank individuals and the genetic overlap with stroke, depression and Alzheimer’s disease Stroke,
Markus, HS. and Schmidt, R., 2018 (Accepted for publication). Genetics of Vascular Cognitive Impairment Stroke,
Markus, HS. and Larsson, S., 2018 (Accepted for publication). Does Treating Vascular Risk Factors Prevent Dementia and Alzheimer’s Disease? A Systematic Review and Meta-Analysis Journal of Alzheimer's Disease,
Rubinsztein, DC., Anttlla, V. and hundreds of other authors, , 2018 (Accepted for publication). Analysis of Shared Heritability in Common Disorders of the Brain Science,
Cole, JW., Xu, H., Ryan, K., Jaworek, T., Dueker, N., McArdle, P., Gaynor, B., Cheng, Y-C., O'Connell, J., Bevan, S., Malik, R., Ahmed, NU., Amouyel, P., Anjum, S., Bis, JC., Crosslin, D., Danesh, J., Engelter, ST., Fornage, M., Frossard, P., Gieger, C., Giese, A-K., Grond-Ginsbach, C., Kee Ho, W., Holliday, E., Hopewell, J., Hussain, M., Iqbal, W., Jabeen, S., Jannes, J., Kamal, A., Kamatani, Y., Kanse, S., Kloss, M., Lathrop, M., Leys, D., Lindgren, A., Longstreth Jr, WT., Mahmood, K., Meisinger, C., Metso, TM., Mosley Jr, T., Muller-Nurasyid, M., Norrving, B., Parati, E., Peters, A., Pezzini, A., Quereshi, I., Rashreed, A., Rauf, A., Salam, T., Shen, J., Slowik, A., Stanne, T., Strauch, K., Tatlisumak, T., Thijs, VN., Tiedt, S., Traylor, M., Waldenberger, M., Walters, M., Zhao, W., Boncoraglio, G., Debette, S., Jern, C., Levi, C., Markus, H., Meschia, J., Rolfs, A., Rothwell, P., Saleheen, D., Seshadri, S., Sharma, P., Sudlow, C., Worrall, B., METASTROKE Consortium of the ISGC, , WTCCC-2 Consortium, , Stine, OC., Kittner, SJ. and Mitchell, BD., 2018 (Accepted for publication). Genetics of the Thrombomodulin-Endothelial Cell Protein C Receptor System and the Risk of Early-Onset Ischemic Stroke PLoS ONE,
2018
Nannucci, S., Rinnoci, V., Pracucci, G., MacKinnon, AD., Pescini, F., Adib-Samii, P., Bianchi, S., Dotti, MT., Federico, A., Inzitari, D., Markus, HS. and Pantoni, L., 2018. Location, number and factors associated with cerebral microbleeds in an Italian-British cohort of CADASIL patients. PLoS One, v. 13
Doi: http://doi.org/10.1371/journal.pone.0190878
Bonati, LH., Gregson, J., Dobson, J., McCabe, DJH., Nederkoorn, PJ., van der Worp, HB., de Borst, GJ., Richards, T., Cleveland, T., Müller, MD., Wolff, T., Engelter, ST., Lyrer, PA., Brown, MM. and International Carotid Stenting Study investigators, , 2018. Restenosis and risk of stroke after stenting or endarterectomy for symptomatic carotid stenosis in the International Carotid Stenting Study (ICSS): secondary analysis of a randomised trial. Lancet Neurol, v. 17
Doi: http://doi.org/10.1016/S1474-4422(18)30195-9
Larsson, SC., Traylor, M., Mishra, A., Howson, JMM., Michaëlsson, K., Markus, HS. and MEGASTROKE Project of the International Stroke Genetics Consortium, , 2018. Serum 25-Hydroxyvitamin D Concentrations and Ischemic Stroke and Its Subtypes. Stroke, v. 49
Doi: http://doi.org/10.1161/STROKEAHA.118.022242
Woo, D., Anderson, CD., Maguire, J., Fornage, M., Lee, J-M., Seshadri, S., Markus, HS., Majersik, JJ., Jimenez-Conde, J., Crawford, K., Lindgren, AG. and Debette, S., 2018. Top research priorities for stroke genetics. Lancet Neurol, v. 17
Doi: http://doi.org/10.1016/S1474-4422(18)30243-6
Malik, R., Rannikmäe, K., Traylor, M., Georgakis, MK., Sargurupremraj, M., Markus, HS., Hopewell, JC., Debette, S., Sudlow, CLM., Dichgans, M. and MEGASTROKE consortium and the International Stroke Genetics Consortium, , 2018. Genome-wide meta-analysis identifies 3 novel loci associated with stroke. Ann Neurol, v. 84
Doi: http://doi.org/10.1002/ana.25369
Larsson, SC., Traylor, M. and Markus, HS., 2018. Circulating Vitamin K₁ Levels in Relation to Ischemic Stroke and Its Subtypes: A Mendelian Randomization Study. Nutrients, v. 10
Doi: http://doi.org/10.3390/nu10111575
Benjamin, P., Trippier, S., Lawrence, AJ., Lambert, C., Zeestraten, E., Williams, OA., Patel, B., Morris, RG., Barrick, TR., MacKinnon, AD. and Markus, HS., 2018. Lacunar Infarcts, but Not Perivascular Spaces, Are Predictors of Cognitive Decline in Cerebral Small-Vessel Disease. Stroke, v. 49
Doi: http://doi.org/10.1161/STROKEAHA.117.017526
Corovic, A., Kelly, S. and Markus, HS., 2018. Cerebral amyloid angiopathy associated with inflammation: A systematic review of clinical and imaging features and outcome. Int J Stroke, v. 13
Doi: http://doi.org/10.1177/1747493017741569
Naylor, AR., Ricco, J-B., de Borst, GJ., Debus, S., de Haro, J., Halliday, A., Hamilton, G., Kakisis, J., Kakkos, S., Lepidi, S., Markus, HS., McCabe, DJ., Roy, J., Sillesen, H., van den Berg, JC., Vermassen, F., Esvs Guidelines Committee, , Kolh, P., Chakfe, N., Hinchliffe, RJ., Koncar, I., Lindholt, JS., Vega de Ceniga, M., Verzini, F., Esvs Guideline Reviewers, , Archie, J., Bellmunt, S., Chaudhuri, A., Koelemay, M., Lindahl, A-K., Padberg, F. and Venermo, M., 2018. Editor's Choice - Management of Atherosclerotic Carotid and Vertebral Artery Disease: 2017 Clinical Practice Guidelines of the European Society for Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg, v. 55
Doi: http://doi.org/10.1016/j.ejvs.2017.06.021
Bath, PM., Woodhouse, LJ., Appleton, JP., Beridze, M., Christensen, H., Dineen, RA., Flaherty, K., Duley, L., England, TJ., Havard, D., Heptinstall, S., James, M., Kasonde, C., Krishnan, K., Markus, HS., Montgomery, AA., Pocock, S., Randall, M., Ranta, A., Robinson, TG., Scutt, P., Venables, GS. and Sprigg, N., 2018. Triple versus guideline antiplatelet therapy to prevent recurrence after acute ischaemic stroke or transient ischaemic attack: the TARDIS RCT. Health Technol Assess, v. 22
Doi: http://doi.org/10.3310/hta22480
Franceschini, N., Giambartolomei, C., de Vries, PS., Finan, C., Bis, JC., Huntley, RP., Lovering, RC., Tajuddin, SM., Winkler, TW., Graff, M., Kavousi, M., Dale, C., Smith, AV., Hofer, E., van Leeuwen, EM., Nolte, IM., Lu, L., Scholz, M., Sargurupremraj, M., Pitkänen, N., Franzén, O., Joshi, PK., Noordam, R., Marioni, RE., Hwang, S-J., Musani, SK., Schminke, U., Palmas, W., Isaacs, A., Correa, A., Zonderman, AB., Hofman, A., Teumer, A., Cox, AJ., Uitterlinden, AG., Wong, A., Smit, AJ., Newman, AB., Britton, A., Ruusalepp, A., Sennblad, B., Hedblad, B., Pasaniuc, B., Penninx, BW., Langefeld, CD., Wassel, CL., Tzourio, C., Fava, C., Baldassarre, D., O'Leary, DH., Teupser, D., Kuh, D., Tremoli, E., Mannarino, E., Grossi, E., Boerwinkle, E., Schadt, EE., Ingelsson, E., Veglia, F., Rivadeneira, F., Beutner, F., Chauhan, G., Heiss, G., Snieder, H., Campbell, H., Völzke, H., Markus, HS., Deary, IJ., Jukema, JW., de Graaf, J., Price, J., Pott, J., Hopewell, JC., Liang, J., Thiery, J., Engmann, J., Gertow, K., Rice, K., Taylor, KD., Dhana, K., Kiemeney, LALM., Lind, L., Raffield, LM., Launer, LJ., Holdt, LM., Dörr, M., Dichgans, M., Traylor, M., Sitzer, M., Kumari, M., Kivimaki, M., Nalls, MA., Melander, O., Raitakari, O., Franco, OH., Rueda-Ochoa, OL., Roussos, P., Whincup, PH., Amouyel, P., Giral, P., Anugu, P., Wong, Q., Malik, R., Rauramaa, R., Burkhardt, R., Hardy, R., Schmidt, R., de Mutsert, R., Morris, RW., Strawbridge, RJ., Wannamethee, SG., Hägg, S., Shah, S., McLachlan, S., Trompet, S., Seshadri, S., Kurl, S., Heckbert, SR., Ring, S., Harris, TB., Lehtimäki, T., Galesloot, TE., Shah, T., de Faire, U., Plagnol, V., Rosamond, WD., Post, W., Zhu, X., Zhang, X., Guo, X., Saba, Y., MEGASTROKE Consortium, , Dehghan, A., Seldenrijk, A., Morrison, AC., Hamsten, A., Psaty, BM., van Duijn, CM., Lawlor, DA., Mook-Kanamori, DO., Bowden, DW., Schmidt, H., Wilson, JF., Wilson, JG., Rotter, JI., Wardlaw, JM., Deanfield, J., Halcox, J., Lyytikäinen, L-P., Loeffler, M., Evans, MK., Debette, S., Humphries, SE., Völker, U., Gudnason, V., Hingorani, AD., Björkegren, JLM., Casas, JP. and O'Donnell, CJ., 2018. GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes. Nat Commun, v. 9
Doi: http://doi.org/10.1038/s41467-018-07340-5
Larsson, SC., Traylor, M., Markus, HS. and Michaëlsson, K., 2018. Serum Parathyroid Hormone, 25-Hydroxyvitamin D, and Risk of Alzheimer's Disease: A Mendelian Randomization Study. Nutrients, v. 10
Doi: http://doi.org/10.3390/nu10091243
Hindy, G., Engström, G., Larsson, SC., Traylor, M., Markus, HS., Melander, O., Orho-Melander, M. and Stroke Genetics Network (SiGN), , 2018. Role of Blood Lipids in the Development of Ischemic Stroke and its Subtypes: A Mendelian Randomization Study. Stroke, v. 49
Doi: http://doi.org/10.1161/STROKEAHA.117.019653
Farmery, JHR., Smith, ML., NIHR BioResource - Rare Diseases, and Lynch, AG., 2018. Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Sci Rep, v. 8
Doi: http://doi.org/10.1038/s41598-018-31524-0
Brookes, RL., Crichton, S., Wolfe, CDA., Yi, Q., Li, L., Hankey, GJ., Rothwell, PM. and Markus, HS., 2018. Sodium Valproate, a Histone Deacetylase Inhibitor, Is Associated With Reduced Stroke Risk After Previous Ischemic Stroke or Transient Ischemic Attack. Stroke, v. 49
Doi: http://doi.org/10.1161/STROKEAHA.117.016674
Hollocks, MJ., Brookes, RL., Morris, RG. and Markus, HS., 2018. The Brief Memory and Executive Test (BMET): A cognitive screening tool to detect and differentiate vascular cognitive impairment and Alzheimer's disease. Int J Geriatr Psychiatry, v. 33
Doi: http://doi.org/10.1002/gps.4787
Horsburgh, K., Wardlaw, JM., van Agtmael, T., Allan, SM., Ashford, MLJ., Bath, PM., Brown, R., Berwick, J., Cader, MZ., Carare, RO., Davis, JB., Duncombe, J., Farr, TD., Fowler, JH., Goense, J., Granata, A., Hall, CN., Hainsworth, AH., Harvey, A., Hawkes, CA., Joutel, A., Kalaria, RN., Kehoe, PG., Lawrence, CB., Lockhart, A., Love, S., Macleod, MR., Macrae, IM., Markus, HS., McCabe, C., McColl, BW., Meakin, PJ., Miller, A., Nedergaard, M., O'Sullivan, M., Quinn, TJ., Rajani, R., Saksida, LM., Smith, C., Smith, KJ., Touyz, RM., Trueman, RC., Wang, T., Williams, A., Williams, SCR. and Work, LM., 2018. Small vessels, dementia and chronic diseases - molecular mechanisms and pathophysiology. Clin Sci (Lond), v. 132
Doi: http://doi.org/10.1042/CS20171620
Bath, PM., Woodhouse, LJ., Appleton, JP., Beridze, M., Christensen, H., Dineen, RA., Duley, L., England, TJ., Flaherty, K., Havard, D., Heptinstall, S., James, M., Krishnan, K., Markus, HS., Montgomery, AA., Pocock, SJ., Randall, M., Ranta, A., Robinson, TG., Scutt, P., Venables, GS., Sprigg, N. and TARDIS Investigators, , 2018. Antiplatelet therapy with aspirin, clopidogrel, and dipyridamole versus clopidogrel alone or aspirin and dipyridamole in patients with acute cerebral ischaemia (TARDIS): a randomised, open-label, phase 3 superiority trial. Lancet, v. 391
Doi: http://doi.org/10.1016/S0140-6736(17)32849-0
Bersano, A., Bedini, G., Markus, HS., Vitali, P., Colli-Tibaldi, E., Taroni, F., Gellera, C., Baratta, S., Mosca, L., Carrera, P., Ferrari, M., Cereda, C., Grieco, G., Lanfranconi, S., Mazucchelli, F., Zarcone, D., De Lodovici, ML., Bono, G., Boncoraglio, GB., Parati, EA., Calloni, MV., Perrone, P., Bordo, BM., Motto, C., Agostoni, E., Pezzini, A., Padovani, A., Micieli, G., Cavallini, A., Molini, G., Sasanelli, F., Sessa, M., Comi, G., Checcarelli, N., Carmerlingo, M., Corato, M., Marcheselli, S., Fusi, L., Grampa, G., Uccellini, D., Beretta, S., Ferrarese, C., Incorvaia, B., Tadeo, CS., Adobbati, L., Silani, V., Faragò, G., Trobia, N., Grond-Ginsbach, C., Candelise, L. and Lombardia GENS-group, , 2018. The role of clinical and neuroimaging features in the diagnosis of CADASIL. Journal of Neurology, v. 265
Doi: http://doi.org/10.1007/s00415-018-9072-8
Le Heron, C., Manohar, S., Plant, O., Muhammed, K., Griffanti, L., Nemeth, A., Douaud, G., Markus, HS. and Husain, M., 2018. Dysfunctional effort-based decision-making underlies apathy in genetic cerebral small vessel disease. Brain, v. 141
Doi: http://doi.org/10.1093/brain/awy257
Campbell, BCV., van Zwam, WH., Goyal, M., Menon, BK., Dippel, DWJ., Demchuk, AM., Bracard, S., White, P., Dávalos, A., Majoie, CBLM., van der Lugt, A., Ford, GA., de la Ossa, NP., Kelly, M., Bourcier, R., Donnan, GA., Roos, YBWEM., Bang, OY., Nogueira, RG., Devlin, TG., van den Berg, LA., Clarençon, F., Burns, P., Carpenter, J., Berkhemer, OA., Yavagal, DR., Pereira, VM., Ducrocq, X., Dixit, A., Quesada, H., Epstein, J., Davis, SM., Jansen, O., Rubiera, M., Urra, X., Micard, E., Lingsma, HF., Naggara, O., Brown, S., Guillemin, F., Muir, KW., van Oostenbrugge, RJ., Saver, JL., Jovin, TG., Hill, MD., Mitchell, PJ. and HERMES collaborators, , 2018. Effect of general anaesthesia on functional outcome in patients with anterior circulation ischaemic stroke having endovascular thrombectomy versus standard care: a meta-analysis of individual patient data. Lancet Neurol, v. 17
Doi: http://doi.org/10.1016/S1474-4422(17)30407-6
2017 (Accepted for publication)
Lohner, V., Brookes, RL., Hollocks, MJ., Morris, RG. and Markus, HS., 2017 (Accepted for publication). Apathy, but not depression, is associated with executive dysfunction in cerebral small vessel disease. PLoS One, v. 12
Doi: http://doi.org/10.1371/journal.pone.0176943
Markus, HS., Larsson, SC., Kuker, W., Schulz, UG., Ford, I., Rothwell, PM. and Clifton, A., 2017 (Accepted for publication). Stenting for symptomatic vertebral artery stenosis: The Vertebral Artery Ischaemia Stenting Trial Neurology,
Doi: http://doi.org/10.1212/WNL.0000000000004385
Evans, NR., Tarkin, JM., Buscombe, JR., Markus, HS., Rudd, JHF. and Warburton, EA., 2017 (Accepted for publication). PET imaging of the neurovascular interface in cerebrovascular disease Nature Reviews Neurology, v. 13
Doi: http://doi.org/10.1038/nrneurol.2017.129
Brookes, RL., Crichton, S., Wolfe, CDA., Yi, Q., Li, L., Hankey, GJ., Rothwell, PM. and Markus, HS., 2017 (Accepted for publication). Sodium valproate, an HDAC inhibitor, is associated with reduced stroke risk after previous ischaemic stroke or TIA Stroke,
Jacobs, LCA. and Markus, HS., 2017 (Accepted for publication). Vascular Risk Factor Profiles Differ Between MRI Defined Subtypes of Younger Onset Lacunar Stroke Stroke, v. 48
Doi: http://doi.org/10.1161/STROKEAHA.117.017813
Croall, I., Tozer, D., Moynihan, B., Khan, U., O'Brien, J., Morris, R., Cambridge, V., Barrick, T., Blamire, A., Ford, G. and Markus, HS., 2017 (Accepted for publication). Effect of Standard vs Intensive Blood Pressure Control on Cerebral Blood Flow in Small Vessel Disease
The PRESERVE Randomized Clinical Trial JAMA Neurology,
Doi: http://doi.org/10.1001/jamaneurol.2017.5153
Farmery, , Smith, M. and Lynch, AG., 2017 (Accepted for publication). Telomerecat: A ploidyagnostic method for estimating telomere length from whole genome sequencing data Scientific Reports,
Traylor, M., Curtis, C., Patel, H., Breen, G., Hyuck Lee, S., Xu, X., Newhouse, S., Dobson, R., Steer, S., Cope, AP., Markus, HS., Lewis, CM. and Scott, IC., 2017 (Accepted for publication). Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case-control study Rheumatology,
Doi: http://doi.org/10.1093/rheumatology/kex048
Danesh, J. and Howson, J., 2017 (Accepted for publication). Multi-ancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes Nature Genetics,
Doi: http://doi.org/10.1038/s41588-018-0058-3
2017
Burgess, S., Haycock, P., Markus, HS. and Willeit, P., 2017. Mendelian randomization study of the association between telomere length and risk of cancer and non-neoplastic diseases JAMA - Journal of the American Medical Association,
Doi: http://doi.org/10.1001/jamaoncol.2016.5945
Larsson, SC., Scott, RA., Traylor, M., Langenberg, CC., Hindy, G., Melander, O., Orho-Melander, M., Seshadri, S., Wareham, NJ., Markus, HS. and METASTROKE Collaboration and NINDS Stroke Genetics Network (SiGN), , 2017. Type 2 diabetes, glucose, insulin, BMI, and ischemic stroke subtypes: Mendelian randomization study Neurology, v. 89
Doi: http://doi.org/10.1212/WNL.0000000000004173
Tuladhar, AM., Lawrence, A., Norris, DG., Barrick, TR., Markus, HS. and de Leeuw, F-E., 2017. Disruption of rich club organisation in cerebral small vessel disease. Hum Brain Mapp, v. 38
Doi: http://doi.org/10.1002/hbm.23479
Larsson, SC., King, A., Madigan, J., Levi, C., Norris, JW. and Markus, HS., 2017. Prognosis of carotid dissecting aneurysms: Results from CADISS and a systematic review Neurology, v. 88
Doi: http://doi.org/10.1212/WNL.0000000000003617
Carss, KJ., Arno, G., Erwood, M., Stephens, J., Sanchis-Juan, A., Hull, S., Megy, K., Grozeva, D., Dewhurst, E., Malka, S., Plagnol, V., Penkett, C., Stirrups, K., Rizzo, R., Wright, G., Josifova, D., Bitner-Glindzicz, M., Scott, RH., Clement, E., Allen, L., Armstrong, R., Brady, AF., Carmichael, J., Chitre, M., Henderson, RHH., Hurst, J., MacLaren, RE., Murphy, E., Paterson, J., Rosser, E., Thompson, DA., Wakeling, E., Ouwehand, WH., Michaelides, M., Moore, AT., NIHR-BioResource Rare Diseases Consortium, , Webster, AR. and Raymond, FL., 2017. Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease American Journal of Human Genetics, v. 100
Doi: http://doi.org/10.1016/j.ajhg.2016.12.003
Mok, VCT., Lam, BYK., Wong, A., Ko, H., Markus, HS. and Wong, LKS., 2017. Early-onset and delayed-onset poststroke dementia - revisiting the mechanisms. Nat Rev Neurol, v. 13
Doi: http://doi.org/10.1038/nrneurol.2017.16
Metoki, A., Brookes, RL., Zeestraten, E., Lawrence, AJ., Morris, RG., Barrick, TR., Markus, HS. and Charlton, RA., 2017. Mnemonic function in small vessel disease and associations with white matter tract microstructure. Neuropsychologia, v. 104
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Di Donato, I., Bianchi, S., De Stefano, N., Dichgans, M., Dotti, MT., Duering, M., Jouvent, E., Korczyn, AD., Lesnik-Oberstein, SAJ., Malandrini, A., Markus, HS., Pantoni, L., Penco, S., Rufa, A., Sinanović, O., Stojanov, D. and Federico, A., 2017. Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) as a model of small vessel disease: update on clinical, diagnostic, and management aspects. BMC Med, v. 15
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Rutten-Jacobs, LCA., Markus, HS. and UK Young Lacunar Stroke DNA Study, , 2017. Vascular Risk Factor Profiles Differ Between Magnetic Resonance Imaging-Defined Subtypes of Younger-Onset Lacunar Stroke. Stroke, v. 48
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Arno, G., Carss, KJ., Hull, S., Zihni, C., Robson, AG., Fiorentino, A., UK Inherited Retinal Disease Consortium, , Hardcastle, AJ., Holder, GE., Cheetham, ME., Plagnol, V., NIHR Bioresource - Rare Diseases Consortium, , Moore, AT., Raymond, FL., Matter, K., Balda, MS. and Webster, AR., 2017. Biallelic Mutation of ARHGEF18, Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration. Am J Hum Genet, v. 100
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Williams, OA., Zeestraten, EA., Benjamin, P., Lambert, C., Lawrence, AJ., Mackinnon, AD., Morris, RG., Markus, HS., Charlton, RA. and Barrick, TR., 2017. Diffusion tensor image segmentation of the cerebrum provides a single measure of cerebral small vessel disease severity related to cognitive change. Neuroimage Clin, v. 16
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Larsson, SC., Traylor, M., Malik, R., Dichgans, M., Burgess, S., Markus, HS. and CoSTREAM Consortium, on behalf of the International Genomics of Alzheimer’s Project, , 2017. Modifiable pathways in Alzheimer's disease: Mendelian randomisation analysis. BMJ, v. 359
Malik, R., Dau, T., Gonik, M., Sivakumar, A., Deredge, DJ., Edeleva, EV., Götzfried, J., van der Laan, SW., Pasterkamp, G., Beaufort, N., Seixas, S., Bevan, S., Lincz, LF., Holliday, EG., Burgess, AI., Rannikmäe, K., Minnerup, J., Kriebel, J., Waldenberger, M., Müller-Nurasyid, M., Lichtner, P., Saleheen, D., International Stroke Genetics Consortium, , Rothwell, PM., Levi, C., Attia, J., Sudlow, CLM., Braun, D., Markus, HS., Wintrode, PL., Berger, K., Jenne, DE. and Dichgans, M., 2017. Common coding variant in SERPINA1 increases the risk for large artery stroke. Proc Natl Acad Sci U S A, v. 114
Doi: http://doi.org/10.1073/pnas.1616301114
Larsson, SC., Traylor, M., Burgess, S. and Markus, HS., 2017. Genetically-Predicted Adult Height and Alzheimer's Disease Journal of Alzheimer's Disease, v. 60
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Tan, Y., Traylor, M., Rutten-Jacobs, L. and Markus, H., 2017. New insights into mechanisms of small vessel disease stroke from genetics Clinical Science, v. 131
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Hainsworth, AH., Minett, T., Andoh, J., Forster, G., Bhide, I., Barrick, TR., Elderfield, K., Jeevahan, J., Markus, HS. and Bridges, LR., 2017. Neuropathology of White Matter Lesions, Blood-Brain Barrier Dysfunction, and Dementia. Stroke, v. 48
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Vassos, E., Di Forti, M., Coleman, J., Iyegbe, C., Prata, D., Euesden, J., O'Reilly, P., Curtis, C., Kolliakou, A., Patel, H., Newhouse, S., Traylor, M., Ajnakina, O., Mondelli, V., Marques, TR., Gardner-Sood, P., Aitchison, KJ., Powell, J., Atakan, Z., Greenwood, KE., Smith, S., Ismail, K., Pariante, C., Gaughran, F., Dazzan, P., Markus, HS., David, AS., Lewis, CM., Murray, RM. and Breen, G., 2017. An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis. Biol Psychiatry, v. 81
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Traylor, M., Rutten-Jacobs, L., Curtis, C., Patel, H., Breen, G., Newhouse, S., Lewis, CM. and Markus, HS., 2017. Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study. Neurol Genet, v. 3
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Thomas, LC., Hall, LA., Attia, JR., Holliday, EG., Markus, HS. and Levi, CR., 2017. Seasonal Variation in Spontaneous Cervical Artery Dissection: Comparing between UK and Australian Sites. J Stroke Cerebrovasc Dis, v. 26
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Zeestraten, EA., Lawrence, AJ., Lambert, C., Benjamin, P., Brookes, RL., Mackinnon, AD., Morris, RG., Barrick, TR. and Markus, HS., 2017. Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease. Neurology, v. 89
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Bath, PM., Appleton, JP., Beridze, M., Christensen, H., Dineen, RA., Duley, L., England, TJ., Heptinstall, S., James, M., Krishnan, K., Markus, HS., Pocock, S., Ranta, A., Robinson, TG., Flaherty, K., Scutt, P., Venables, GS., Woodhouse, LJ. and Sprigg, N., 2017. Baseline characteristics of the 3096 patients recruited into the 'Triple Antiplatelets for Reducing Dependency after Ischemic Stroke' trial. Int J Stroke, v. 12
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Lubitz, SA., Parsons, OE., Anderson, CD., Benjamin, EJ., Malik, R., Weng, L-C., Dichgans, M., Sudlow, CL., Rothwell, PM., Rosand, J., Ellinor, PT., Markus, HS. and Traylor, M., 2017. Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms Stroke, v. 48
Doi: http://doi.org/10.1161/STROKEAHA.116.016198
Rannikmäe, K., Sivakumaran, V., Millar, H., Malik, R., Anderson, CD., Chong, M., Dave, T., Falcone, GJ., Fernandez-Cadenas, I., Jimenez-Conde, J., Lindgren, A., Montaner, J., O'Donnell, M., Paré, G., Radmanesh, F., Rost, NS., Slowik, A., Söderholm, M., Traylor, M., Pulit, SL., Seshadri, S., Worrall, BB., Woo, D., Markus, HS., Mitchell, BD., Dichgans, M., Rosand, J., Sudlow, CLM. and Stroke Genetics Network (SiGN), METASTROKE Collaboration, and International Stroke Genetics Consortium (ISGC), , 2017. COL4A2 is associated with lacunar ischemic stroke and deep ICH: Meta-analyses among 21,500 cases and 40,600 controls. Neurology, v. 89
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Muir, KW., Ford, GA., Messow, C-M., Ford, I., Murray, A., Clifton, A., Brown, MM., Madigan, J., Lenthall, R., Robertson, F., Dixit, A., Cloud, GC., Wardlaw, J., Freeman, J., White, P. and PISTE Investigators, , 2017. Endovascular therapy for acute ischaemic stroke: the Pragmatic Ischaemic Stroke Thrombectomy Evaluation (PISTE) randomised, controlled trial. J Neurol Neurosurg Psychiatry, v. 88
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Croall, ID., Lohner, V., Moynihan, B., Khan, U., Hassan, A., O'Brien, JT., Morris, RG., Tozer, DJ., Cambridge, VC., Harkness, K., Werring, DJ., Blamire, AM., Ford, GA., Barrick, TR. and Markus, HS., 2017. Using DTI to assess white matter microstructure in cerebral small vessel disease (SVD) in multicentre studies Clinical Science, v. 131
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Phuah, C-L., Dave, T., Malik, R., Raffeld, MR., Ayres, AM., Goldstein, JN., Viswanathan, A., Greenberg, SM., Jagiella, JM., Hansen, BM., Norrving, B., Jimenez-Conde, J., Roquer, J., Pichler, A., Enzinger, C., Montaner, J., Fernandez-Cadenas, I., Lindgren, A., Slowik, A., Schmidt, R., Biffi, A., Rost, N., Langefeld, CD., Markus, HS., Mitchell, BD., Worrall, BB., Kittner, SJ., Woo, D., Dichgans, M., Rosand, J., Anderson, CD., METASTROKE, , NINDS-SiGN Consortium, and International Stroke Genetics Consortium, , 2017. Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke. Brain, v. 140
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McGlasson, S., Rannikmäe, K., Bevan, S., Logan, C., Bicknell, LS., Jury, A., UK Young Lacunar Stroke Study, , Jackson, AP., Markus, HS., Sudlow, C. and Hunt, DPJ., 2017. Rare variants of the 3'-5' DNA exonuclease TREX1 in early onset small vessel stroke. Wellcome Open Res, v. 2
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2016
Bersano, A., Markus, HS., Quaglini, S., Arbustini, E., Lanfranconi, S., Micieli, G., Boncoraglio, GB., Taroni, F., Gellera, C., Baratta, S., Penco, S., Mosca, L., Grasso, M., Carrera, P., Ferrari, M., Cereda, C., Grieco, G., Corti, S., Ronchi, D., Bassi, MT., Obici, L., Parati, EA., Pezzini, A., De Lodovici, ML., Verrengia, EP., Bono, G., Mazucchelli, F., Zarcone, D., Calloni, MV., Perrone, P., Bordo, BM., Colombo, A., Padovani, A., Cavallini, A., Beretta, S., Ferrarese, C., Motto, C., Agostoni, E., Molini, G., Sasanelli, F., Corato, M., Marcheselli, S., Sessa, M., Comi, G., Checcarelli, N., Guidotti, M., Uccellini, D., Capitani, E., Tancredi, L., Arnaboldi, M., Incorvaia, B., Tadeo, CS., Fusi, L., Grampa, G., Merlini, G., Trobia, N., Comi, GP., Braga, M., Vitali, P., Baron, P., Grond-Ginsbach, C., Candelise, L. and Lombardia GENS Group*, , 2016. Clinical Pregenetic Screening for Stroke Monogenic Diseases: Results From Lombardia GENS Registry. Stroke, v. 47
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Larsson, SC., Wallin, A., Wolk, A. and Markus, HS., 2016. Differing association of alcohol consumption with different stroke types: a systematic review and meta-analysis. BMC Med, v. 14
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Østergaard, L., Engedal, TS., Moreton, F., Hansen, MB., Wardlaw, JM., Dalkara, T., Markus, HS. and Muir, KW., 2016. Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline. J Cereb Blood Flow Metab, v. 36
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Kenyan Bacteraemia Study Group, , Wellcome Trust Case Control Consortium 2 (WTCCC2), , Rautanen, A., Pirinen, M., Mills, TC., Rockett, KA., Strange, A., Ndungu, AW., Naranbhai, V., Gilchrist, JJ., Bellenguez, C., Freeman, C., Band, G., Bumpstead, SJ., Edkins, S., Giannoulatou, E., Gray, E., Dronov, S., Hunt, SE., Langford, C., Pearson, RD., Su, Z., Vukcevic, D., Macharia, AW., Uyoga, S., Ndila, C., Mturi, N., Njuguna, P., Mohammed, S., Berkley, JA., Mwangi, I., Mwarumba, S., Kitsao, BS., Lowe, BS., Morpeth, SC., Khandwalla, I., Kilifi Bacteraemia Surveillance Group, , Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, J., Markus, HS., Mathew, CG., Palmer, CNA., Plomin, R., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Deloukas, P., Peltonen, L., Williams, TN., Scott, JAG., Chapman, SJ., Donnelly, P., Hill, AVS. and Spencer, CCA., 2016. Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children. Am J Hum Genet, v. 98
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Benjamin, P., Zeestraten, E., Lambert, C., Ster, IC., Williams, OA., Lawrence, AJ., Patel, B., MacKinnon, AD., Barrick, TR. and Markus, HS., 2016. Progression of MRI markers in cerebral small vessel disease: Sample size considerations for clinical trials. J Cereb Blood Flow Metab, v. 36
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Cheng, Y-C., Stanne, TM., Giese, A-K., Ho, WK., Traylor, M., Amouyel, P., Holliday, EG., Malik, R., Xu, H., Kittner, SJ., Cole, JW., O'Connell, JR., Danesh, J., Rasheed, A., Zhao, W., Engelter, S., Grond-Ginsbach, C., Kamatani, Y., Lathrop, M., Leys, D., Thijs, V., Metso, TM., Tatlisumak, T., Pezzini, A., Parati, EA., Norrving, B., Bevan, S., Rothwell, PM., Sudlow, C., Slowik, A., Lindgren, A., Walters, MR., WTCCC-2 Consortium, , Jannes, J., Shen, J., Crosslin, D., Doheny, K., Laurie, CC., Kanse, SM., Bis, JC., Fornage, M., Mosley, TH., Hopewell, JC., Strauch, K., Müller-Nurasyid, M., Gieger, C., Waldenberger, M., Peters, A., Meisinger, C., Ikram, MA., Longstreth, WT., Meschia, JF., Seshadri, S., Sharma, P., Worrall, B., Jern, C., Levi, C., Dichgans, M., Boncoraglio, GB., Markus, HS., Debette, S., Rolfs, A., Saleheen, D. and Mitchell, BD., 2016. Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2. Stroke, v. 47
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Traylor, M., Malik, R., Nalls, MA., Cotlarciuc, I., Radmanesh, F., Thorleifsson, G., Hanscombe, KB., Langefeld, C., Saleheen, D., Rost, NS., Yet, I., Spector, TD., Bell, JT., Hannon, E., Mill, J., Chauhan, G., Debette, S., Bis, JC., Longstreth, WT., Ikram, MA., Launer, LJ., Seshadri, S., METASTROKE, UK Young Lacunar DNA Study, NINDS Stroke Genetics Network, Neurology Working Group of the CHARGE Consortium, Monica Anne Hamilton-Bruce, , Jimenez-Conde, J., Cole, JW., Schmidt, R., Słowik, A., Lemmens, R., Lindgren, A., Melander, O., Grewal, RP., Sacco, RL., Rundek, T., Rexrode, K., Arnett, DK., Johnson, JA., Benavente, OR., Wasssertheil-Smoller, S., Lee, J-M., Pulit, SL., Wong, Q., Rich, SS., de Bakker, PIW., McArdle, PF., Woo, D., Anderson, CD., Xu, H., Heitsch, L., Fornage, M., Jern, C., Stefansson, K., Thorsteinsdottir, U., Gretarsdottir, S., Lewis, CM., Sharma, P., Sudlow, CLM., Rothwell, PM., Boncoraglio, GB., Thijs, V., Levi, C., Meschia, JF., Rosand, J., Kittner, SJ., Mitchell, BD., Dichgans, M., Worrall, BB., Markus, HS. and International Stroke Genetics Consortium, , 2016. Genetic Variation at 16q24.2 is associated with small vessel stroke Annals of Neurology,
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Zeestraten, EA., Benjamin, P., Lambert, C., Lawrence, AJ., Williams, OA., Morris, RG., Barrick, TR. and Markus, HS., 2016. Application of Diffusion Tensor Imaging Parameters to Detect Change in Longitudinal Studies in Cerebral Small Vessel Disease. PLoS One, v. 11
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Prins, BP., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, PE., Guterriez Achury, J., Mistry, V., Bradfield, JP., Valdes, AM., Bras, J., Shatunov, A., PAGE Consortium, , International Stroke Genetics Consortium, , Systemic Sclerosis consortium, , Treat OA consortium, , DIAGRAM Consortium, , CARDIoGRAMplusC4D Consortium, , ALS consortium, , International Parkinson’s Disease Genomics Consortium, , Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, , CKDGen consortium, , GERAD1 Consortium, , International Consortium for Blood Pressure, , Schizophrenia Working Group of the Psychiatric Genomics Consortium, , Inflammation Working Group of the CHARGE Consortium, , Lu, C., Han, B., Raychaudhuri, S., Bevan, S., Mayes, MD., Tsoi, LC., Evangelou, E., Nair, RP., Grant, SFA., Polychronakos, C., Radstake, TRD., van Heel, DA., Dunstan, ML., Wood, NW., Al-Chalabi, A., Dehghan, A., Hakonarson, H., Markus, HS., Elder, JT., Knight, J., Arking, DE., Spector, TD., Koeleman, BPC., van Duijn, CM., Martin, J., Morris, AP., Weersma, RK., Wijmenga, C., Munroe, PB., Perry, JRB., Pouget, JG., Jamshidi, Y., Snieder, H. and Alizadeh, BZ., 2016. Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study. PLoS Med, v. 13
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Traylor, M., Zhang, CR., Adib-Samii, P., Devan, WJ., Parsons, OE., Lanfranconi, S., Gregory, S., Cloonan, L., Falcone, GJ., Radmanesh, F., Fitzpatrick, K., Kanakis, A., Barrick, TR., Moynihan, B., Lewis, CM., Boncoraglio, GB., Lemmens, R., Thijs, V., Sudlow, C., Wardlaw, J., Rothwell, PM., Meschia, JF., Worrall, BB., Levi, C., Bevan, S., Furie, KL., Dichgans, M., Rosand, J., Markus, HS., Rost, N. and International Stroke Genetics Consortium, , 2016. Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke. Neurology, v. 86
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Deng, QQ., Tang, J., Chen, C., Markus, H., Huang, YN., Zhao, H., Ratanakorn, D., Wong, KSL. and Fu, JH., 2016. The curative effect comparison of two kinds of therapeutic regimens on decreasing the relative intensity of microembolic signal in CLAIR trial. J Neurol Sci, v. 367
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Rutten-Jacobs, LCA., Traylor, M., Adib-Samii, P., Thijs, V., Sudlow, C., Rothwell, PM., Boncoraglio, G., Dichgans, M., Meschia, J., Maguire, J., Levi, C., Rost, NS., Rosand, J., Hassan, A., Bevan, S. and Markus, HS., 2016. Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype. Stroke, v. 47
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Robinson, PC., Leo, PJ., Pointon, JJ., Harris, J., Cremin, K., Bradbury, LA., Wellcome Trust Case Control Consortium, , Australasian Osteoporosis Genetics Consortium (AOGC), , Stebbings, S., Harrison, AA., Evans, DM., Duncan, EL., Wordsworth, BP., Brown, MA. and Australasian Osteoporosis Genetics Consortium AOGC, , 2016. The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis. Genes Immun, v. 17
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Traylor, M., Adib-Samii, P., Harold, D., Alzheimer's Disease Neuroimaging Initiative, , International Stroke Genetics Consortium (ISGC), UK Young Lacunar Stroke DNA resource, , Dichgans, M., Williams, J., Lewis, CM., Markus, HS., METASTROKE, and International Genomics of Alzheimer's Project (IGAP), investigators, , 2016. Shared genetic contribution to Ischaemic Stroke and Alzheimer's Disease. Ann Neurol, v. 79
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Tuladhar, AM., van Uden, IWM., Rutten-Jacobs, LCA., Lawrence, A., van der Holst, H., van Norden, A., de Laat, K., van Dijk, E., Claassen, JAHR., Kessels, RPC., Markus, HS., Norris, DG. and de Leeuw, F-E., 2016. Structural network efficiency predicts conversion to dementia. Neurology, v. 86
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Lambert, C., Benjamin, P., Zeestraten, E., Lawrence, AJ., Barrick, TR. and Markus, HS., 2016. Longitudinal patterns of leukoaraiosis and brain atrophy in symptomatic small vessel disease. Brain, v. 139
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Rosenberg, GA., Wallin, A., Wardlaw, JM., Markus, HS., Montaner, J., Wolfson, L., Iadecola, C., Zlokovic, BV., Joutel, A., Dichgans, M., Duering, M., Schmidt, R., Korczyn, AD., Grinberg, LT., Chui, HC. and Hachinski, V., 2016. Consensus statement for diagnosis of subcortical small vessel disease. J Cereb Blood Flow Metab, v. 36
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Gulli, G., Rutten-Jacobs, LCA., Kalra, L., Rudd, AG., Wolfe, CDA. and Markus, HS., 2016. Differences in the distribution of stroke subtypes in a UK black stroke population - final results from the South London Ethnicity and Stroke Study. BMC Med, v. 14
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Lambert, C., Sam Narean, J., Benjamin, P., Zeestraten, E., Barrick, TR. and Markus, HS., 2015. Characterising the grey matter correlates of leukoaraiosis in cerebral small vessel disease. Neuroimage Clin, v. 9
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CADISS trial investigators, , Markus, HS., Hayter, E., Levi, C., Feldman, A., Venables, G. and Norris, J., 2015. Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial. Lancet Neurol, v. 14
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Benjamin, P., Viessmann, O., MacKinnon, AD., Jezzard, P. and Markus, HS., 2015. 7 Tesla MRI in cerebral small vessel disease. Int J Stroke, v. 10
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Traylor, M., Bevan, S., Baron, J-C., Hassan, A., Lewis, CM. and Markus, HS., 2015. Genetic Architecture of Lacunar Stroke. Stroke, v. 46
Doi: http://doi.org/10.1161/STROKEAHA.115.009485
Brookes, RL., Hollocks, MJ., Khan, U., Morris, RG. and Markus, HS., 2015. The Brief Memory and Executive Test (BMET) for detecting vascular cognitive impairment in small vessel disease: a validation study. BMC Med, v. 13
Doi: http://doi.org/10.1186/s12916-015-0290-y
Rutten-Jacobs, LCA., Traylor, M., Adib-Samii, P., Thijs, V., Sudlow, C., Rothwell, PM., Boncoraglio, G., Dichgans, M., Bevan, S., Meschia, J., Levi, C., Rost, NS., Rosand, J., Hassan, A. and Markus, HS., 2015. Common NOTCH3 Variants and Cerebral Small-Vessel Disease. Stroke, v. 46
Doi: http://doi.org/10.1161/STROKEAHA.114.008540
Kilarski, LL., Rutten-Jacobs, LCA., Bevan, S., Baker, R., Hassan, A., Hughes, DA., Markus, HS. and UK Young Lacunar Stroke DNA Study, , 2015. Prevalence of CADASIL and Fabry Disease in a Cohort of MRI Defined Younger Onset Lacunar Stroke. PLoS One, v. 10
Doi: http://doi.org/10.1371/journal.pone.0136352
Alassar, A., Soppa, G., Edsell, M., Rich, P., Roy, D., Chis Ster, I., Joyce, R., Valencia, O., Barrick, T., Howe, F., Moat, N., Morris, R., Markus, HS. and Jahangiri, M., 2015. Incidence and mechanisms of cerebral ischemia after transcatheter aortic valve implantation compared with surgical aortic valve replacement Annals of Thoracic Surgery, v. 99
Doi: http://doi.org/10.1016/j.athoracsur.2014.09.054
Rutten-Jacobs, LCA., Traylor, M., Thijs, V., Sudlow, C., Rothwell, PM., Boncoraglio, G., Dichgans, M., Levi, C., Bevan, S. and Markus, HM., 2015. Association of MTHFR genotype with lacunar stroke supports causal role for homocysteine INTERNATIONAL JOURNAL OF STROKE, v. 10
King, A., Madigan, J., Clifton, A., Norris, J. and Markus, HS., 2015. Pseudoaneurysms in cervical artery dissection: Results from a multicenter randomized trial - Cervical Artery Dissection in Stroke Study (CADISS) INTERNATIONAL JOURNAL OF STROKE, v. 10
Rannikmäe, K., Davies, G., Thomson, PA., Bevan, S., Devan, WJ., Falcone, GJ., Traylor, M., Anderson, CD., Battey, TWK., Radmanesh, F., Deka, R., Woo, JG., Martin, LJ., Jimenez-Conde, J., Selim, M., Brown, DL., Silliman, SL., Kidwell, CS., Montaner, J., Langefeld, CD., Slowik, A., Hansen, BM., Lindgren, AG., Meschia, JF., Fornage, M., Bis, JC., Debette, S., Ikram, MA., Longstreth, WT., Schmidt, R., Zhang, CR., Yang, Q., Sharma, P., Kittner, SJ., Mitchell, BD., Holliday, EG., Levi, CR., Attia, J., Rothwell, PM., Poole, DL., Boncoraglio, GB., Psaty, BM., Malik, R., Rost, N., Worrall, BB., Dichgans, M., Van Agtmael, T., Woo, D., Markus, HS., Seshadri, S., Rosand, J., Sudlow, CLM., METASTROKE Consortium, , CHARGE WMH Group, , ISGC ICH GWAS Study Collaboration, , WMH in Ischemic Stroke GWAS Study Collaboration, and International Stroke Genetics Consortium, , 2015. Common variation in COL4A1/COL4A2 is associated with sporadic cerebral small vessel disease. Neurology, v. 84
Doi: http://doi.org/10.1212/WNL.0000000000001309
Brookes, RL., Hollocks, MJ., Khan, U., Morris, RG. and Markus, HS., 2015. The Brief Memory and Executive Test (BMET) for detecting vascular cognitive impairment in small vessel disease: a validation study. BMC Med, v. 13
Doi: http://doi.org/10.1186/s12916-015-0290-y
King, A., Madigan, J., Clifton, A., Norris, J. and Markus, HS., 2015. Neuro-radiological confirmation of dissection: Lessons learned from a multicenter randomized trial - Cervical Artery Dissection in Stroke Study (CADISS) INTERNATIONAL JOURNAL OF STROKE, v. 10
Traylor, M., Markus, H. and Lewis, CM., 2015. Homogeneous case subgroups increase power in genetic association studies European Journal of Human Genetics, v. 23
Doi: http://doi.org/10.1038/ejhg.2014.194
Markus, HS., 2015. The Cervical Artery Dissection in Stroke Study (CADISS) - One year follow-up results INTERNATIONAL JOURNAL OF STROKE, v. 10
2014
Opherk, C., Gonik, M., Duering, M., Malik, R., Jouvent, E., Hervé, D., Adib-Samii, P., Bevan, S., Pianese, L., Silvestri, S., Dotti, MT., De Stefano, N., Liem, M., Boon, EMJ., Pescini, F., Pachai, C., Bracoud, L., Müller-Myhsok, B., Meitinger, T., Rost, N., Pantoni, L., Lesnik Oberstein, S., Federico, A., Ragno, M., Markus, HS., Tournier-Lasserve, E., Rosand, J., Chabriat, H. and Dichgans, M., 2014. Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL. Stroke, v. 45
Doi: http://doi.org/10.1161/STROKEAHA.113.004461
Psychosis Endophenotypes International Consortium, , Wellcome Trust Case-Control Consortium 2, , Bramon, E., Pirinen, M., Strange, A., Lin, K., Freeman, C., Bellenguez, C., Su, Z., Band, G., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S., Gray, E., Dronov, S., Potter, SC., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, SJ., Arranz, MJ., Bakker, S., Bender, S., Bruggeman, R., Cahn, W., Chandler, D., Collier, DA., Crespo-Facorro, B., Dazzan, P., de Haan, L., Di Forti, M., Dragović, M., Giegling, I., Hall, J., Iyegbe, C., Jablensky, A., Kahn, RS., Kalaydjieva, L., Kravariti, E., Lawrie, S., Linszen, DH., Mata, I., McDonald, C., McIntosh, A., Myin-Germeys, I., Ophoff, RA., Pariante, CM., Paunio, T., Picchioni, M., Psychiatric Genomics Consortium, , Ripke, S., Rujescu, D., Sauer, H., Shaikh, M., Sussmann, J., Suvisaari, J., Tosato, S., Toulopoulou, T., Van Os, J., Walshe, M., Weisbrod, M., Whalley, H., Wiersma, D., Blackwell, JM., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, JAZ., Markus, HS., Mathew, CG., Palmer, CNA., Plomin, R., Rautanen, A., Sawcer, SJ., Trembath, RC., Wood, NW., Barroso, I., Peltonen, L., Lewis, CM., Murray, RM., Donnelly, P., Powell, J. and Spencer, CCA., 2014. A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation. Biol Psychiatry, v. 75
Doi: http://doi.org/10.1016/j.biopsych.2013.03.033
Bridges, LR., Andoh, J., Lawrence, AJ., Khoong, CHL., Poon, W., Esiri, MM., Markus, HS. and Hainsworth, AH., 2014. Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people. J Neuropathol Exp Neurol, v. 73
Doi: http://doi.org/10.1097/NEN.0000000000000124
Williams, FMK., Carter, AM., Hysi, PG., Surdulescu, G., Hodgkiss, D., Soranzo, N., Traylor, M., Bevan, S., Dichgans, M., Rothwell, PMW., Sudlow, C., Farrall, M., Silander, K., Kaunisto, M., Wagner, P., Saarela, O., Kuulasmaa, K., Virtamo, J., Salomaa, V., Amouyel, P., Arveiler, D., Ferrieres, J., Wiklund, P-G., Ikram, MA., Hofman, A., Boncoraglio, GB., Parati, EA., Helgadottir, A., Gretarsdottir, S., Thorsteinsdottir, U., Thorleifsson, G., Stefansson, K., Seshadri, S., DeStefano, A., Gschwendtner, A., Psaty, B., Longstreth, W., Mitchell, BD., Cheng, Y-C., Clarke, R., Ferrario, M., Bis, JC., Levi, C., Attia, J., Holliday, EG., Scott, RJ., Fornage, M., Sharma, P., Furie, KL., Rosand, J., Nalls, M., Meschia, J., Mosely, TH., Evans, A., Palotie, A., Markus, HS., Grant, PJ. and Spector, TD., 2014. Ischemic stroke is associated with the ABO locus: The EuroCLOT study (vol 73, pg 16, 2013) ANNALS OF NEUROLOGY, v. 75
Doi: http://doi.org/10.1002/ana.24105
Valenti, R., Pantoni, L. and Markus, HS., 2014. Treatment of vascular risk factors in patients with a diagnosis of Alzheimer's disease: a systematic review. BMC Med, v. 12
Doi: http://doi.org/10.1186/s12916-014-0160-z
Williams, FMK., Carter, AM., Hysi, PG., Surdulescu, G., Hodgkiss, D., Soranzo, N., Traylor, M., Bevan, S., Dichgans, M., Rothwell, PMW., Sudlow, C., Farrall, M., Silander, K., Kaunisto, M., Wagner, P., Saarela, O., Kuulasmaa, K., Virtamo, J., Salomaa, V., Amouyel, P., Arveiler, D., Ferrieres, J., Wiklund, PG., Ikram, MA., Hofman, A., Boncoraglio, GB., Parati, EA., Helgadottir, A., Gretarsdottir, S., Thorsteinsdottir, U., Thorleifsson, G., Stefansson, K., Seshadri, S., DeStefano, A., Gschwendtner, A., Psaty, B., Longstreth, W., Mitchell, BD., Cheng, YC., Clarke, R., Ferrario, M., Bis, JC., Levi, C., Attia, J., Holliday, EG., Scott, RJ., Fornage, M., Sharma, P., Furie, KL., Rosand, J., Nalls, M., Meschia, J., Mosely, TH., Evans, A., Palotie, A., Markus, HS., Grant, PJ. and Spector, TD., 2014. Erratum: Ischemic stroke is associated with the ABO locus: The EuroCLOT study (Annals of Neurology (2013) 73 (16-31)) Annals of Neurology, v. 75
Doi: http://doi.org/10.1002/ana.24105
McArdle, PF., Kittner, SJ., Ay, H., Brown, RD., Meschia, JF., Rundek, T., Wassertheil-Smoller, S., Woo, D., Andsberg, G., Biffi, A., Brenner, DA., Cole, JW., Corriveau, R., de Bakker, PIW., Delavaran, H., Dichgans, M., Grewal, RP., Gwinn, K., Huq, M., Jern, C., Jimenez-Conde, J., Jood, K., Kaplan, RC., Katschnig, P., Katsnelson, M., Labovitz, DL., Lemmens, R., Li, L., Lindgren, A., Markus, HS., Peddareddygari, LR., Pedersén, A., Pera, J., Redfors, P., Roquer, J., Rosand, J., Rost, NS., Rothwell, PM., Sacco, RL., Sharma, P., Slowik, A., Sudlow, C., Thijs, V., Tiedt, S., Valenti, R., Worrall, BB. and NINDS SiGN Study, , 2014. Agreement between TOAST and CCS ischemic stroke classification: the NINDS SiGN study. Neurology, v. 83
Doi: http://doi.org/10.1212/WNL.0000000000000942
Cotlarciuc, I., Malik, R., Holliday, EG., Ahmadi, KR., Paré, G., Psaty, BM., Fornage, M., Hasan, N., Rinne, PE., Ikram, MA., Markus, HS., Rosand, J., Mitchell, BD., Kittner, SJ., Meschia, JF., van Meurs, JBJ., Uitterlinden, AG., Worrall, BB., Dichgans, M., Sharma, P. and METASTROKE and the International Stroke Genetics Consortium, , 2014. Effect of genetic variants associated with plasma homocysteine levels on stroke risk. Stroke, v. 45
Doi: http://doi.org/10.1161/STROKEAHA.114.005208
Dregan, A., Charlton, J., Wolfe, CDA., Gulliford, MC. and Markus, HS., 2014. Is sodium valproate, an HDAC inhibitor, associated with reduced risk of stroke and myocardial infarction? A nested case-control study. Pharmacoepidemiol Drug Saf, v. 23
Doi: http://doi.org/10.1002/pds.3651
Rannikmaae, K., Davies, G., Thomson, P., Devan, W., Bevan, S., Traylor, M., Falcone, GJ., Anderson, C., Rost, N., Woo, D., Markus, H., Seshadri, S., Rosand, J., Van Agtmael, T. and Sudlow, CLM., 2014. The contribution of variants in collagen IV genes to common cerebrovascular phenotypes CEREBROVASCULAR DISEASES, v. 37
Lawrence, AJ., Chung, AW., Morris, RG., Markus, HS. and Barrick, TR., 2014. Structural network efficiency is associated with cognitive impairment in small-vessel disease. Neurology, v. 83
Doi: http://doi.org/10.1212/WNL.0000000000000612
Herbert, V., Brookes, RL., Markus, HS. and Morris, RG., 2014. Verbal fluency in cerebral small vessel disease and Alzheimer's disease. J Int Neuropsychol Soc, v. 20
Doi: http://doi.org/10.1017/S1355617714000101
Dregan, A., Charlton, J., Wolfe, CDA., Gulliford, MC. and Markus, HS., 2014. Is Sodium Valproate, an HDAC inhibitor, associated with reduced stroke risk? A nested case-control study CEREBROVASCULAR DISEASES, v. 37
Benjamin, P., Lawrence, AJ., Lambert, C., Patel, B., Chung, AW., MacKinnon, AD., Morris, RG., Barrick, TR. and Markus, HS., 2014. Strategic lacunes and their relationship to cognitive impairment in cerebral small vessel disease. Neuroimage Clin, v. 4
Doi: http://doi.org/10.1016/j.nicl.2014.05.009
Springelkamp, H., Höhn, R., Mishra, A., Hysi, PG., Khor, C-C., Loomis, SJ., Bailey, JNC., Gibson, J., Thorleifsson, G., Janssen, SF., Luo, X., Ramdas, WD., Vithana, E., Nongpiur, ME., Montgomery, GW., Xu, L., Mountain, JE., Gharahkhani, P., Lu, Y., Amin, N., Karssen, LC., Sim, K-S., van Leeuwen, EM., Iglesias, AI., Verhoeven, VJM., Hauser, MA., Loon, S-C., Despriet, DDG., Nag, A., Venturini, C., Sanfilippo, PG., Schillert, A., Kang, JH., Landers, J., Jonasson, F., Cree, AJ., van Koolwijk, LME., Rivadeneira, F., Souzeau, E., Jonsson, V., Menon, G., Blue Mountains Eye Study—GWAS group, , Weinreb, RN., de Jong, PTVM., Oostra, BA., Uitterlinden, AG., Hofman, A., Ennis, S., Thorsteinsdottir, U., Burdon, KP., NEIGHBORHOOD Consortium, , Wellcome Trust Case Control Consortium 2 (WTCCC2), , Spector, TD., Mirshahi, A., Saw, S-M., Vingerling, JR., Teo, Y-Y., Haines, JL., Wolfs, RCW., Lemij, HG., Tai, E-S., Jansonius, NM., Jonas, JB., Cheng, C-Y., Aung, T., Viswanathan, AC., Klaver, CCW., Craig, JE., Macgregor, S., Mackey, DA., Lotery, AJ., Stefansson, K., Bergen, AAB., Young, TL., Wiggs, JL., Pfeiffer, N., Wong, T-Y., Pasquale, LR., Hewitt, AW., van Duijn, CM. and Hammond, CJ., 2014. Meta-analysis of genome-wide association studies identifies novel loci that influence cupping and the glaucomatous process. Nat Commun, v. 5
Doi: http://doi.org/10.1038/ncomms5883
Hayes, DF., Markus, HS., Leslie, RD. and Topol, EJ., 2014. Personalized medicine: risk prediction, targeted therapies and mobile health technology. BMC Med, v. 12
Doi: http://doi.org/10.1186/1741-7015-12-37
Benjamin, P., Lawrence, AJ., Lambert, C., Mackinnon, A., Barrick, T. and Markus, HS., 2014. Progression of Brain Atrophy in Cerebral Small Vessel Disease. Results from the SCANS study. CEREBROVASCULAR DISEASES, v. 37
Traylor, M., Mäkelä, K-M., Kilarski, LL., Holliday, EG., Devan, WJ., Nalls, MA., Wiggins, KL., Zhao, W., Cheng, Y-C., Achterberg, S., Malik, R., Sudlow, C., Bevan, S., Raitoharju, E., METASTROKE, International Stroke Genetics Consortium, Wellcome Trust Case Consortium 2 (WTCCC2), , Oksala, N., Thijs, V., Lemmens, R., Lindgren, A., Slowik, A., Maguire, JM., Walters, M., Algra, A., Sharma, P., Attia, JR., Boncoraglio, GB., Rothwell, PM., de Bakker, PIW., Bis, JC., Saleheen, D., Kittner, SJ., Mitchell, BD., Rosand, J., Meschia, JF., Levi, C., Dichgans, M., Lehtimäki, T., Lewis, CM. and Markus, HS., 2014. A novel MMP12 locus is associated with large artery atherosclerotic stroke using a genome-wide age-at-onset informed approach. PLoS Genet, v. 10
Doi: http://doi.org/10.1371/journal.pgen.1004469
Postmus, I., Trompet, S., Deshmukh, HA., Barnes, MR., Li, X., Warren, HR., Chasman, DI., Zhou, K., Arsenault, BJ., Donnelly, LA., Wiggins, KL., Avery, CL., Griffin, P., Feng, Q., Taylor, KD., Li, G., Evans, DS., Smith, AV., de Keyser, CE., Johnson, AD., de Craen, AJM., Stott, DJ., Buckley, BM., Ford, I., Westendorp, RGJ., Slagboom, PE., Sattar, N., Munroe, PB., Sever, P., Poulter, N., Stanton, A., Shields, DC., O'Brien, E., Shaw-Hawkins, S., Chen, Y-DI., Nickerson, DA., Smith, JD., Dubé, MP., Boekholdt, SM., Hovingh, GK., Kastelein, JJP., McKeigue, PM., Betteridge, J., Neil, A., Durrington, PN., Doney, A., Carr, F., Morris, A., McCarthy, MI., Groop, L., Ahlqvist, E., Welcome Trust Case Control Consortium, , Bis, JC., Rice, K., Smith, NL., Lumley, T., Whitsel, EA., Stürmer, T., Boerwinkle, E., Ngwa, JS., O'Donnell, CJ., Vasan, RS., Wei, W-Q., Wilke, RA., Liu, C-T., Sun, F., Guo, X., Heckbert, SR., Post, W., Sotoodehnia, N., Arnold, AM., Stafford, JM., Ding, J., Herrington, DM., Kritchevsky, SB., Eiriksdottir, G., Launer, LJ., Harris, TB., Chu, AY., Giulianini, F., MacFadyen, JG., Barratt, BJ., Nyberg, F., Stricker, BH., Uitterlinden, AG., Hofman, A., Rivadeneira, F., Emilsson, V., Franco, OH., Ridker, PM., Gudnason, V., Liu, Y., Denny, JC., Ballantyne, CM., Rotter, JI., Adrienne Cupples, L., Psaty, BM., Palmer, CNA., Tardif, J-C., Colhoun, HM., Hitman, G., Krauss, RM., Wouter Jukema, J. and Caulfield, MJ., 2014. Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins. Nat Commun, v. 5
Doi: http://doi.org/10.1038/ncomms6068
Davis, OSP., Band, G., Pirinen, M., Haworth, CMA., Meaburn, EL., Kovas, Y., Harlaar, N., Docherty, SJ., Hanscombe, KB., Trzaskowski, M., Curtis, CJC., Strange, A., Freeman, C., Bellenguez, C., Su, Z., Pearson, R., Vukcevic, D., Langford, C., Deloukas, P., Hunt, S., Gray, E., Dronov, S., Potter, SC., Tashakkori-Ghanbaria, A., Edkins, S., Bumpstead, SJ., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, JAZ., Markus, HS., Mathew, CG., Palmer, CNA., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Barroso, I., Peltonen, L., Dale, PS., Petrill, SA., Schalkwyk, LS., Craig, IW., Lewis, CM., Price, TS., Wellcome Trust Case Control Consortium 2, , Donnelly, P., Plomin, R. and Spencer, CCA., 2014. The correlation between reading and mathematics ability at age twelve has a substantial genetic component. Nat Commun, v. 5
Doi: http://doi.org/10.1038/ncomms5204
Lau, AY., Zhao, Y., Chen, C., Leung, TW., Fu, J., Huang, Y., Suwanwela, NC., Han, Z., Tan, KS., Ratanakorn, D., Markus, HS., Wong, KS. and CLAIR Study Investigators, , 2014. Dual antiplatelets reduce microembolic signals in patients with transient ischemic attack and minor stroke: subgroup analysis of CLAIR study. Int J Stroke, v. 9 Suppl A100
Doi: http://doi.org/10.1111/ijs.12003
Kilarski, LL., Achterberg, S., Devan, WJ., Traylor, M., Malik, R., Lindgren, A., Pare, G., Sharma, P., Slowik, A., Thijs, V., Walters, M., Worrall, BB., Sale, MM., Algra, A., Kappelle, LJ., Wijmenga, C., Norrving, B., Sandling, JK., Rönnblom, L., Goris, A., Franke, A., Sudlow, C., Rothwell, PM., Levi, C., Holliday, EG., Fornage, M., Psaty, B., Gretarsdottir, S., Thorsteinsdottir, U., Seshadri, S., Mitchell, BD., Kittner, S., Clarke, R., Hopewell, JC., Bis, JC., Boncoraglio, GB., Meschia, J., Ikram, MA., Hansen, BM., Montaner, J., Thorleifsson, G., Stefanson, K., Rosand, J., de Bakker, PIW., Farrall, M., Dichgans, M., Markus, HS., Bevan, S. and GARNET Collaborative Research Group, Wellcome Trust Case Control Consortium 2, Australian Stroke Genetic Collaborative, the METASTROKE Consortium, and the International Stroke Genetics Consortium, , 2014. Meta-analysis in more than 17,900 cases of ischemic stroke reveals a novel association at 12q24.12. Neurology, v. 83
Doi: http://doi.org/10.1212/WNL.0000000000000707
Brookes, RL., Herbert, V., Paul, S., Hannesdottir, K., Markus, HS. and Morris, RG., 2014. Executive dysfunction, awareness deficits and quality of life in patients with cerebral small vessel disease: a structural equation model. Neuropsychology, v. 28
Doi: http://doi.org/10.1037/neu0000015
Brookes, RL., Herbert, V., Lawrence, AJ., Morris, RG. and Markus, HS., 2014. Depression in small-vessel disease relates to white matter ultrastructural damage, not disability. Neurology, v. 83
Doi: http://doi.org/10.1212/WNL.0000000000000882
Reinhard, M., Schwarzer, G., Briel, M., Altamura, C., Palazzo, P., King, A., Bornstein, NM., Petersen, N., Motschall, E., Hetzel, A., Marshall, RS., Klijn, CJM., Silvestrini, M., Markus, HS. and Vernieri, F., 2014. Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease: An individual patient data meta-analysis CEREBROVASCULAR DISEASES, v. 37
Alex, D., Wolfe, CDA., Gulliford, MC. and Markus, HS., 2014. Is sodium valproate, an HDAC inhibitor, associated with reduced stroke risk? A nested case-control study INTERNATIONAL JOURNAL OF STROKE, v. 9
Reinhard, M., Schwarzer, G., Briel, M., Altamura, C., Palazzo, P., King, A., Bornstein, NM., Petersen, N., Motschall, E., Hetzel, A., Marshall, RS., Klijn, CJM., Silvestrini, M., Markus, HS. and Vernieri, F., 2014. Cerebrovascular reactivity predicts stroke in high-grade carotid artery disease. Neurology, v. 83
Doi: http://doi.org/10.1212/WNL.0000000000000888
Dichgans, M., Malik, R., König, IR., Rosand, J., Clarke, R., Gretarsdottir, S., Thorleifsson, G., Mitchell, BD., Assimes, TL., Levi, C., O'Donnell, CJ., Fornage, M., Thorsteinsdottir, U., Psaty, BM., Hengstenberg, C., Seshadri, S., Erdmann, J., Bis, JC., Peters, A., Boncoraglio, GB., März, W., Meschia, JF., Kathiresan, S., Ikram, MA., McPherson, R., Stefansson, K., Sudlow, C., Reilly, MP., Thompson, JR., Sharma, P., Hopewell, JC., Chambers, JC., Watkins, H., Rothwell, PM., Roberts, R., Markus, HS., Samani, NJ., Farrall, M., Schunkert, H., METASTROKE Consortium, , CARDIoGRAM Consortium, , C4D Consortium, and International Stroke Genetics Consortium, , 2014. Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants. Stroke, v. 45
Doi: http://doi.org/10.1161/STROKEAHA.113.002707
Wong, KSL., Wang, Y., Leng, X., Mao, C., Tang, J., Bath, PMW., Markus, HS., Gorelick, PB., Liu, L., Lin, W. and Wang, Y., 2014. Response to letter regarding article, "early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis". Circulation, v. 130
Doi: http://doi.org/10.1161/CIRCULATIONAHA.114.009357
Malik, R., Bevan, S., Nalls, MA., Holliday, EG., Devan, WJ., Cheng, Y-C., Ibrahim-Verbaas, CA., Verhaaren, BFJ., Bis, JC., Joon, AY., de Stefano, AL., Fornage, M., Psaty, BM., Ikram, MA., Launer, LJ., van Duijn, CM., Sharma, P., Mitchell, BD., Rosand, J., Meschia, JF., Levi, C., Rothwell, PM., Sudlow, C., Markus, HS., Seshadri, S., Dichgans, M. and Wellcome Trust Case Control Consortium 2, , 2014. Multilocus genetic risk score associates with ischemic stroke in case-control and prospective cohort studies. Stroke, v. 45
Doi: http://doi.org/10.1161/STROKEAHA.113.002938
Ay, H., Arsava, EM., Andsberg, G., Benner, T., Brown, RD., Chapman, SN., Cole, JW., Delavaran, H., Dichgans, M., Engström, G., Giralt-Steinhauer, E., Grewal, RP., Gwinn, K., Jern, C., Jimenez-Conde, J., Jood, K., Katsnelson, M., Kissela, B., Kittner, SJ., Kleindorfer, DO., Labovitz, DL., Lanfranconi, S., Lee, J-M., Lehm, M., Lemmens, R., Levi, C., Li, L., Lindgren, A., Markus, HS., McArdle, PF., Melander, O., Norrving, B., Peddareddygari, LR., Pedersén, A., Pera, J., Rannikmäe, K., Rexrode, KM., Rhodes, D., Rich, SS., Roquer, J., Rosand, J., Rothwell, PM., Rundek, T., Sacco, RL., Schmidt, R., Schürks, M., Seiler, S., Sharma, P., Slowik, A., Sudlow, C., Thijs, V., Woodfield, R., Worrall, BB. and Meschia, JF., 2014. Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network. Stroke, v. 45
Doi: http://doi.org/10.1161/STROKEAHA.114.007362
Mäkelä, K-M., Traylor, M., Oksala, N., Kleber, ME., Seppälä, I., Lyytikäinen, L-P., Hernesniemi, JA., Kähönen, M., Bevan, S., Rothwell, PM., Sudlow, C., Dichgans, M., Wellcome Trust Case Control Consortium 2 (WTCCC2), , Delgado, G., Grammer, TB., Scharnagl, H., Markus, HS., März, W. and Lehtimäki, T., 2014. Association of the novel single-nucleotide polymorphism which increases oxidized low-density lipoprotein levels with cerebrovascular disease events. Atherosclerosis, v. 234
Doi: http://doi.org/10.1016/j.atherosclerosis.2014.03.002
Holliday, EG., Traylor, M., Malik, R., Bevan, S., Maguire, J., Koblar, SA., Sturm, J., Hankey, GJ., Oldmeadow, C., McEvoy, M., Sudlow, C., Rothwell, PM., Coresh, J., Hamet, P., Tremblay, J., Turner, ST., de Andrade, M., Rao, M., Schmidt, R., Crick, PA., Robino, A., Peralta, CA., Jukema, JW., Mitchell, P., Rosas, SE., Wang, JJ., Scott, RJ., Dichgans, M., Mitchell, BD., Kao, WHL., Fox, CS., Levi, C., Attia, J., Markus, HS. and CKDGen Consortium and the International Stroke Genetics Consortium, , 2014. Polygenic overlap between kidney function and large artery atherosclerotic stroke. Stroke, v. 45
Doi: http://doi.org/10.1161/STROKEAHA.114.006609
2013 (No publication date)
Traylor, M., Farrall, M., Holliday, EG., Sudlow, C., Hopewell, JC., Cheng, Y-C., Fornage, M., Ikram, MA., Malik, R., Bevan, S., Thorsteinsdottir, U., Nalls, MA., Longstreth, WT., Wiggins, KL., Yadav, S., Parati, EA., DeStefano, AL., Worrall, BB., Kittner, SJ., Khan, MS., Reiner, AP., Helgadottir, A., Achterberg, S., Fernandez-Cadenas, I., Abboud, S., Schmidt, R., Walters, M., Chen, W-M., Ringelstein, EB., O Donnell, M., Ho, WK., Pera, J., Lemmens, R., Norrving, B., Higgins, P., Benn, M., Sale, M., Kuhlenbaumer, G., Doney, ASF., Vicente, AM., Delavaran, H., Algra, A., Davies, G., Oliveira, SA., Palmer, CNA., Deary, I., Schmidt, H., Pandolfo, M., Montaner, J., Carty, C., de Bakker, PIW., Kostulas, K., Ferro, JM., van Zuydam, NR., Valdimarsson, E., Nordestgaard, BG., Lindgren, A., Thijs, V., slowik, A., Salaheen, D., Pare, G., Berger, K., Thorliefsson, G., Collaborative, TAG., WTCCC2, , Hofman, A., Mosley, TH., Mitchell, BD., Furie, K., Clarke, R., Levi, C., Seshadri, S., Gschwendtner, A., Boncoraglio, GB., Sharma, P., Bis, JC., Gretarsdottir, S., Psaty, BM., Rothwell, PM., Rosand, J., Meschia, JF., Stefansson, K., Dichgans, M., Markus, HS. and Consortium, TISG., 2013 (No publication date). Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genomewide association studies Lancet Neurology,
2013
Thomas, J., Parsons, O., Traylor, M., Li, L., Bevan, S., Sudlow, C., Rothwell, P., Markus, H., Levi, CR., Holliday, L. and Attia, J., 2013. The impact of CCS and TOAST classification systems on genetic associations with ischaemic stroke INTERNATIONAL JOURNAL OF STROKE, v. 8
Markus, HS., Mäkelä, KM., Bevan, S., Raitoharju, E., Oksala, N., Bis, JC., O'Donnell, C., Hainsworth, A. and Lehtimäki, T., 2013. Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis Stroke, v. 44
Doi: http://doi.org/10.1161/STROKEAHA.111.000217
Benjamin, P., Lawrence, A., Patel, B., Chung, A., Mackinnon, AD., Lambert, C., Morris, RG., Barrick, TR. and Markus, HS., 2013. Thalamic lacunes in regions with connectivity to the prefrontal cortex are associated with impaired processing speed in cerebral small vessel disease CEREBROVASCULAR DISEASES, v. 35
Gulli, G., Marquardt, L., Rothwell, PM. and Markus, HS., 2013. Stroke risk after posterior circulation stroke/transient ischemic attack and its relationship to site of vertebrobasilar stenosis: Pooled data analysis from prospective studies Stroke, v. 44
Doi: http://doi.org/10.1161/STROKEAHA.112.669929
Charlton, RA., Barrick, TR., Markus, HS. and Morris, RG., 2013. Verbal working and long-term episodic memory associations with white matter microstructure in normal aging investigated using tract-based spatial statistics. Psychol Aging, v. 28
Doi: http://doi.org/10.1037/a0032668
Adib-Samii, P., Rost, N., Traylor, M., Devan, W., Biffi, A., Lanfranconi, S., Fitzpatrick, K., Bevan, S., Kanakis, A., Valant, V., Gschwendtner, A., Malik, R., Richie, A., Gamble, D., Segal, H., Parati, EA., Ciusani, E., Holliday, EG., Maguire, J., Wardlaw, J., Worrall, B., Bis, J., Wiggins, KL., Longstreth, W., Kittner, SJ., Cheng, Y-C., Mosley, T., Falcone, GJ., Furie, KL., Leiva-Salinas, C., Lau, BC., Khan, MS., Sharma, P., Fornage, M., Mitchell, BD., Psaty, BM., Sudlow, C., Levi, C., Boncoraglio, GB., Rothwell, PM., Meschia, J., Dichgans, M., Rosand, J. and Markus, HS., 2013. 17q25 Locus Is Associated With White Matter Hyperintensity Volume in Ischemic Stroke, But Not With Lacunar Stroke Status STROKE, v. 44
Doi: http://doi.org/10.1161/STROKEAHA.113.679936
Wong, KS., Wang, Y., Leng, X., Mao, C., Tang, J., Bath, PMW., Markus, HS., Gorelick, PB., Liu, L., Lin, W. and Wang, Y., 2013. Early Dual versus Mono Antiplatelet Therapy for Acute Non-Cardioembolic Ischemic Stroke or Transient Ischemic Attack: An Updated Systematic Review and Meta-Analysis CEREBROVASCULAR DISEASES, v. 36
Parsons, O., Traylor, M., Linxin, L., Bevan, S., Sudlow, C., Rothwell, PM., Levi, C. and Markus, HS., 2013. Impact of stroke classification systems on strength of genetic associations with ischaemic stroke CEREBROVASCULAR DISEASES, v. 35
Patel, B., Lawrence, AJ., Chung, AW., Rich, P., MacKinnon, AD., Morris, RG., Barrick, TR. and Markus, HS., 2013. Cerebral microbleeds and cognition in patients with symptomatic small vessel disease Stroke, v. 44
Doi: http://doi.org/10.1161/STROKEAHA.112.670216
Ripke, S., O'Dushlaine, C., Chambert, K., Moran, JL., Kähler, AK., Akterin, S., Bergen, SE., Collins, AL., Crowley, JJ., Fromer, M., Kim, Y., Lee, SH., Magnusson, PKE., Sanchez, N., Stahl, EA., Williams, S., Wray, NR., Xia, K., Bettella, F., Borglum, AD., Bulik-Sullivan, BK., Cormican, P., Craddock, N., de Leeuw, C., Durmishi, N., Gill, M., Golimbet, V., Hamshere, ML., Holmans, P., Hougaard, DM., Kendler, KS., Lin, K., Morris, DW., Mors, O., Mortensen, PB., Neale, BM., O'Neill, FA., Owen, MJ., Milovancevic, MP., Posthuma, D., Powell, J., Richards, AL., Riley, BP., Ruderfer, D., Rujescu, D., Sigurdsson, E., Silagadze, T., Smit, AB., Stefansson, H., Steinberg, S., Suvisaari, J., Tosato, S., Verhage, M., Walters, JT., Multicenter Genetic Studies of Schizophrenia Consortium, , Levinson, DF., Gejman, PV., Kendler, KS., Laurent, C., Mowry, BJ., O'Donovan, MC., Owen, MJ., Pulver, AE., Riley, BP., Schwab, SG., Wildenauer, DB., Dudbridge, F., Holmans, P., Shi, J., Albus, M., Alexander, M., Campion, D., Cohen, D., Dikeos, D., Duan, J., Eichhammer, P., Godard, S., Hansen, M., Lerer, FB., Liang, K-Y., Maier, W., Mallet, J., Nertney, DA., Nestadt, G., Norton, N., O'Neill, FA., Papadimitriou, GN., Ribble, R., Sanders, AR., Silverman, JM., Walsh, D., Williams, NM., Wormley, B., Psychosis Endophenotypes International Consortium, , Arranz, MJ., Bakker, S., Bender, S., Bramon, E., Collier, D., Crespo-Facorro, B., Hall, J., Iyegbe, C., Jablensky, A., Kahn, RS., Kalaydjieva, L., Lawrie, S., Lewis, CM., Lin, K., Linszen, DH., Mata, I., McIntosh, A., Murray, RM., Ophoff, RA., Powell, J., Rujescu, D., Van Os, J., Walshe, M., Weisbrod, M., Wiersma, D., Wellcome Trust Case Control Consortium 2, , Donnelly, P., Barroso, I., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, AP., Deloukas, P., Duncanson, A., Jankowski, J., Markus, HS., Mathew, CG., Palmer, CNA., Plomin, R., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Spencer, CCA., Band, G., Bellenguez, C., Freeman, C., Hellenthal, G., Giannoulatou, E., Pirinen, M., Pearson, RD., Strange, A., Su, Z., Vukcevic, D., Donnelly, P., Langford, C., Hunt, SE., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, SJ., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, OT., Liddle, J., Potter, SC., Ravindrarajah, R., Ricketts, M., Tashakkori-Ghanbaria, A., Waller, MJ., Weston, P., Widaa, S., Whittaker, P., Barroso, I., Deloukas, P., Mathew, CG., Blackwell, JM., Brown, MA., Corvin, AP., McCarthy, MI., Spencer, CCA., Bramon, E., Corvin, AP., O'Donovan, MC., Stefansson, K., Scolnick, E., Purcell, S., McCarroll, SA., Sklar, P., Hultman, CM. and Sullivan, PF., 2013. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet, v. 45
Doi: http://doi.org/10.1038/ng.2742
LeishGEN Consortium, , Wellcome Trust Case Control Consortium 2, , Fakiola, M., Strange, A., Cordell, HJ., Miller, EN., Pirinen, M., Su, Z., Mishra, A., Mehrotra, S., Monteiro, GR., Band, G., Bellenguez, C., Dronov, S., Edkins, S., Freeman, C., Giannoulatou, E., Gray, E., Hunt, SE., Lacerda, HG., Langford, C., Pearson, R., Pontes, NN., Rai, M., Singh, SP., Smith, L., Sousa, O., Vukcevic, D., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, J., Markus, HS., Mathew, CG., Palmer, CNA., Plomin, R., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Wilson, ME., Deloukas, P., Peltonen, L., Christiansen, F., Witt, C., Jeronimo, SMB., Sundar, S., Spencer, CCA., Blackwell, JM. and Donnelly, P., 2013. Common variants in the HLA-DRB1-HLA-DQA1 HLA class II region are associated with susceptibility to visceral leishmaniasis. Nat Genet, v. 45
Doi: http://doi.org/10.1038/ng.2518
Meschia, JF., Arnett, DK., Ay, H., Brown, RD., Benavente, OR., Cole, JW., de Bakker, PIW., Dichgans, M., Doheny, KF., Fornage, M., Grewal, RP., Gwinn, K., Jern, C., Conde, JJ., Johnson, JA., Jood, K., Laurie, CC., Lee, J-M., Lindgren, A., Markus, HS., McArdle, PF., McClure, LA., Mitchell, BD., Schmidt, R., Rexrode, KM., Rich, SS., Rosand, J., Rothwell, PM., Rundek, T., Sacco, RL., Sharma, P., Shuldiner, AR., Slowik, A., Wassertheil-Smoller, S., Sudlow, C., Thijs, VNS., Woo, D., Worrall, BB., Wu, O., Kittner, SJ. and NINDS SiGN Study, , 2013. Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes. Stroke, v. 44
Doi: http://doi.org/10.1161/STROKEAHA.113.001857
Sabater-Lleal, M., Huang, J., Chasman, D., Naitza, S., Dehghan, A., Johnson, AD., Teumer, A., Reiner, AP., Folkersen, L., Basu, S., Rudnicka, AR., Trompet, S., Mälarstig, A., Baumert, J., Bis, JC., Guo, X., Hottenga, JJ., Shin, S-Y., Lopez, LM., Lahti, J., Tanaka, T., Yanek, LR., Oudot-Mellakh, T., Wilson, JF., Navarro, P., Huffman, JE., Zemunik, T., Redline, S., Mehra, R., Pulanic, D., Rudan, I., Wright, AF., Kolcic, I., Polasek, O., Wild, SH., Campbell, H., Curb, JD., Wallace, R., Liu, S., Eaton, CB., Becker, DM., Becker, LC., Bandinelli, S., Räikkönen, K., Widen, E., Palotie, A., Fornage, M., Green, D., Gross, M., Davies, G., Harris, SE., Liewald, DC., Starr, JM., Williams, FMK., Grant, PJ., Spector, TD., Strawbridge, RJ., Silveira, A., Sennblad, B., Rivadeneira, F., Uitterlinden, AG., Franco, OH., Hofman, A., van Dongen, J., Willemsen, G., Boomsma, DI., Yao, J., Swords Jenny, N., Haritunians, T., McKnight, B., Lumley, T., Taylor, KD., Rotter, JI., Psaty, BM., Peters, A., Gieger, C., Illig, T., Grotevendt, A., Homuth, G., Völzke, H., Kocher, T., Goel, A., Franzosi, MG., Seedorf, U., Clarke, R., Steri, M., Tarasov, KV., Sanna, S., Schlessinger, D., Stott, DJ., Sattar, N., Buckley, BM., Rumley, A., Lowe, GD., McArdle, WL., Chen, M-H., Tofler, GH., Song, J., Boerwinkle, E., Folsom, AR., Rose, LM., Franco-Cereceda, A., Teichert, M., Ikram, MA., Mosley, TH., Bevan, S., Dichgans, M., Rothwell, PM., Sudlow, CLM., Hopewell, JC., Chambers, JC., Saleheen, D., Kooner, JS., Danesh, J., Nelson, CP., Erdmann, J., Reilly, MP., Kathiresan, S., Schunkert, H., Morange, P-E., Ferrucci, L., Eriksson, JG., Jacobs, D., Deary, IJ., Soranzo, N., Witteman, JCM., de Geus, EJC., Tracy, RP., Hayward, C., Koenig, W., Cucca, F., Jukema, JW., Eriksson, P., Seshadri, S., Markus, HS., Watkins, H., Samani, NJ., VTE Consortium, , STROKE Consortium, , Wellcome Trust Case Control Consortium 2 (WTCCC2), , C4D Consortium, , CARDIoGRAM Consortium, , Wallaschofski, H., Smith, NL., Tregouet, D., Ridker, PM., Tang, W., Strachan, DP., Hamsten, A. and O'Donnell, CJ., 2013. Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation, v. 128
Doi: http://doi.org/10.1161/CIRCULATIONAHA.113.002251
Markus, HS., van der Worp, HB. and Rothwell, PM., 2013. Posterior circulation ischaemic stroke and transient ischaemic attack: diagnosis, investigation, and secondary prevention. Lancet Neurol, v. 12
Doi: http://doi.org/10.1016/S1474-4422(13)70211-4
Yadav, S., Cotlarciuc, I., Munroe, PB., Khan, MS., Nalls, MA., Bevan, S., Cheng, YC., Chen, WM., Malik, R., McCarthy, NS., Holliday, EG., Speed, D., Hasan, N., Pucek, M., Rinne, PE., Sever, P., Stanton, A., Shields, DC., Maguire, JM., McEvoy, M., Scott, RJ., Ferrucci, L., Macleod, MJ., Attia, J., Markus, HS., Sale, MM., Worrall, BB., Mitchell, BD., Dichgans, M., Sudlow, C., Meschia, JF., Rothwell, PM., Caulfield, M., Sharma, P. and Consortium, ISG., 2013. Genome-Wide Analysis of Blood Pressure Variability and Ischemic Stroke. Stroke,
Doi: http://doi.org/10.1161/STROKEAHA.113.002186
Kaudewitz, D., Lee, R., Willeit, P., McGregor, R., Markus, HS., Kiechl, S., Zampetaki, A., Storey, RF., Channon, KM. and Mayr, M., 2013. Impact of intravenous heparin on quantification of circulating microRNAs in patients with coronary artery disease. Thromb Haemost, v. 110
Doi: http://doi.org/10.1160/TH13-05-0368
Willeit, P., Zampetaki, A., Dudek, K., Kaudewitz, D., King, A., Kirkby, NS., Crosby-Nwaobi, R., Prokopi, M., Drozdov, I., Langley, SR., Sivaprasad, S., Markus, HS., Mitchell, JA., Warner, TD., Kiechl, S. and Mayr, M., 2013. Circulating MicroRNAs as novel biomarkers for platelet activation Circulation Research, v. 112
Doi: http://doi.org/10.1161/CIRCRESAHA.111.300539
Bonati, LH., Ederle, J., Dobson, J., Engelter, S., Featherstone, RL., Gaines, PA., Beard, JD., Venables, GS., Markus, HS., Clifton, A., Sandercock, P. and Brown, MM., 2013. Length of carotid stenosis predicts peri-procedural stroke or death and restenosis in patients randomized to endovascular treatment or endarterectomy International Journal of Stroke,
Williams, FMK., Carter, AM., Hysi, PG., Surdulescu, G., Hodgkiss, D., Soranzo, N., Traylor, M., Bevan, S., Dichgans, M., Rothwell, PMW., Sudlow, C., Farrall, M., Silander, K., Kaunisto, M., Wagner, P., Saarela, O., Kuulasmaa, K., Virtamo, J., Salomaa, V., Amouyel, P., Arveiler, D., Ferrieres, J., Wiklund, P-G., Ikram, MA., Hofman, A., Boncoraglio, GB., Parati, EA., Helgadottir, A., Gretarsdottir, S., Thorsteinsdottir, U., Thorleifsson, G., Stefansson, K., Seshadri, S., DeStefano, A., Gschwendtner, A., Psaty, B., Longstreth, W., Mitchell, BD., Cheng, Y-C., Clarke, R., Ferrario, M., Bis, JC., Levi, C., Attia, J., Holliday, EG., Scott, RJ., Fornage, M., Sharma, P., Furie, KL., Rosand, J., Nalls, M., Meschia, J., Mosely, TH., Evans, A., Palotie, A., Markus, HS., Grant, PJ. and Spector, TD., 2013. Ischemic Stroke Is Associated with the ABO Locus: The EuroCLOT Study ANNALS OF NEUROLOGY, v. 73
Doi: http://doi.org/10.1002/ana.23838
Brookes, RL., Hannesdottir, K., Markus, HS. and Morris, RG., 2013. Lack of awareness of neuropsychological deficit in cerebral small vessel disease: The relationship with executive and episodic memory functions JOURNAL OF NEUROPSYCHOLOGY, v. 7
Doi: http://doi.org/10.1111/j.1748-6653.2012.02032.x
Wang, X., Lin, WH., Zhao, YD., Chen, XY., Leung, TW., Chen, C., Fu, J., Markus, H., Hao, Q., Wong, KS. and CLAIR Study Investigators, , 2013. The effectiveness of dual antiplatelet treatment in acute ischemic stroke patients with intracranial arterial stenosis: a subgroup analysis of CLAIR study. Int J Stroke, v. 8
Doi: http://doi.org/10.1111/j.1747-4949.2012.00828.x
Mechelli, R., Umeton, R., Policano, C., Annibali, V., Coarelli, G., Ricigliano, VAG., Vittori, D., Fornasiero, A., Buscarinu, MC., International Multiple Sclerosis Genetics Consortium, , Wellcome Trust Case Control Consortium,2, , Romano, S., Salvetti, M. and Ristori, G., 2013. A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. PLoS One, v. 8
Doi: http://doi.org/10.1371/journal.pone.0063300
Kerry, SM., Markus, HS., Khong, TK., Cloud, GC., Tulloch, J., Coster, D., Ibison, J. and Oakeshott, P., 2013. Home blood pressure monitoring with nurse-led telephone support among patients with hypertension and a history of stroke: A community-based randomized controlled trial CMAJ. Canadian Medical Association Journal, v. 185
Doi: http://doi.org/10.1503/cmaj.120832
Blue Mountains Eye Study (BMES), and Wellcome Trust Case Control Consortium 2 (WTCCC2), , 2013. Genome-wide association study of intraocular pressure identifies the GLCCI1/ICA1 region as a glaucoma susceptibility locus. Hum Mol Genet, v. 22
Doi: http://doi.org/10.1093/hmg/ddt293
Traylor, M., Bevan, S., Rothwell, PM., Sudlow, C., Dichgans, M., Markus, HS. and Lewis, CM., 2013. Using Phenotypic Heterogeneity to Increase the Power of Genome-Wide Association Studies: Application to Age at Onset of Ischaemic Stroke Subphenotypes Genetic Epidemiology, v. 37
Doi: http://doi.org/10.1002/gepi.21729
Wong, KSL., Wang, Y., Leng, X., Mao, C., Tang, J., Bath, PMW., Markus, HS., Gorelick, PB., Liu, L., Lin, W. and Wang, Y., 2013. Early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack: an updated systematic review and meta-analysis. Circulation, v. 128
Doi: http://doi.org/10.1161/CIRCULATIONAHA.113.003187
Lawrence, AJ., Patel, B., Morris, RG., MacKinnon, AD., Rich, PM., Barrick, TR. and Markus, HS., 2013. Mechanisms of Cognitive Impairment in Cerebral Small Vessel Disease: Multimodal MRI Results from the St George's Cognition and Neuroimaging in Stroke (SCANS) Study PLoS ONE, v. 8
Doi: http://doi.org/10.1371/journal.pone.0061014
2012
Geeganage, CM., Diener, HC., Algra, A., Chen, C., Topol, EJ., Dengler, R., Markus, HS., Bath, MW. and Bath, PMW., 2012. Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: Systematic review and meta-analysis of randomized controlled trials Stroke, v. 43
Doi: http://doi.org/10.1161/STROKEAHA.111.637686
ISGC, ISGC., WTCCC2, WTCCC., Bellenguez, C., Bevan, S., Gschwendtner, A., Spencer, CC., Burgess, AI., Pirinen, M., Jackson, CA., Traylor, M., Strange, A., Su, Z., Band, G., Syme, PD., Malik, R., Pera, J., Norrving, B., Lemmens, R., Freeman, C., Schanz, R., James, T., Poole, D., Murphy, L., Segal, H., Cortellini, L., Cheng, YC., Woo, D., Nalls, MA., Müller-Myhsok, B., Meisinger, C., Seedorf, U., Ross-Adams, H., Boonen, S., Wloch-Kopec, D., Valant, V., Slark, J., Furie, K., Delavaran, H., Langford, C., Deloukas, P., Edkins, S., Hunt, S., Gray, E., Dronov, S., Peltonen, L., Gretarsdottir, S., Thorleifsson, G., Thorsteinsdottir, U., Stefansson, K., Boncoraglio, GB., Parati, EA., Attia, J., Holliday, E., Levi, C., Franzosi, MG., Goel, A., Helgadottir, A., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Jankowski, J., Mathew, CG., Palmer, CN., Plomin, R., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Worrall, BB., Kittner, SJ., Mitchell, BD., Kissela, B., Meschia, JF., Thijs, V., Lindgren, A., Macleod, MJ., Slowik, A., Walters, M., Rosand, J., Sharma, P., Farrall, M., Sudlow, CL., Rothwell, PM., Dichgans, M., Donnelly, P. and Markus, HS., 2012. Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic stroke. Nat Genet, v. 44
Doi: http://doi.org/10.1038/ng.1081
Brookes, RL., Hannesdottir, K., Lawrence, R., Morris, RG. and Markus, HS., 2012. Brief memory and executive test: Evaluation of a new screening test for cognitive impairment due to small vessel disease Age and Ageing, v. 41
Doi: http://doi.org/10.1093/ageing/afr172
Holliday, EG., Maguire, JM., Evans, T-J., Koblar, SA., Jannes, J., Sturm, JW., Hankey, GJ., Baker, R., Golledge, J., Parsons, MW., Malik, R., McEvoy, M., Biros, E., Lewis, MD., Lincz, LF., Peel, R., Oldmeadow, C., Smith, W., Moscato, P., Barlera, S., Bevan, S., Bis, JC., Boerwinkle, E., Boncoraglio, GB., Brott, TG., Brown Jr, RD., Cheng, Y-C., Cole, JW., Cotlarciuc, I., Devan, WJ., Fornage, M., Furie, KL., Grétarsdóttir, S., Gschwendtner, A., Ikram, MA., Longstreth Jr, WT., Meschia, JF., Mitchell, BD., Mosley, TH., Nalls, MA., Parati, EA., Psaty, BM., Sharma, P., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Traylor, M., Verhaaren, BFJ., Wiggins, KL., Worrall, BB., Sudlow, C., Rothwell, PM., Farrall, M., Dichgans, M., Rosand, J., Markus, HS., Scott, RJ., Levi, C. and Attia, J., 2012. Common variants at 6p21.1 are associated with large artery atherosclerotic stroke Nature Genetics,
Paul, S., Markus, H. and Moynihan, B., 2012. Patient and carer perspectives on the London hyper-acute stroke unit model INTERNATIONAL JOURNAL OF STROKE, v. 7
Giwa, MO., Williams, J., Elderfield, K., Jiwa, NS., Bridges, LR., Kalaria, RN., Markus, HS., Esiri, MM. and Hainsworth, AH., 2012. Neuropathologic evidence of endothelial changes in cerebral small vessel disease NEUROLOGY, v. 78
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Benjamin, P., Lawrence, AJ., Patel, P., Chung, AW., MacKinnon, A., Morris, R., Barrick, TR. and Markus, HS., 2012. Lacunar infarcts and cognition in cerebral small vessel disease: results from the SCANS study INTERNATIONAL JOURNAL OF STROKE, v. 7
Su, Z., Gay, LJ., Strange, A., Palles, C., Band, G., Whiteman, DC., Lescai, F., Langford, C., Nanji, M., Edkins, S., van der Winkel, A., Levine, D., Sasieni, P., Bellenguez, C., Howarth, K., Freeman, C., Trudgill, N., Tucker, AT., Pirinen, M., Peppelenbosch, MP., van der Laan, LJW., Kuipers, EJ., Drenth, JPH., Peters, WH., Reynolds, JV., Kelleher, DP., McManus, R., Grabsch, H., Prenen, H., Bisschops, R., Krishnadath, K., Siersema, PD., van Baal, JWPM., Middleton, M., Petty, R., Gillies, R., Burch, N., Bhandari, P., Paterson, S., Edwards, C., Penman, I., Vaidya, K., Ang, Y., Murray, I., Patel, P., Ye, W., Mullins, P., Wu, AH., Bird, NC., Dallal, H., Shaheen, NJ., Murray, LJ., Koss, K., Bernstein, L., Romero, Y., Hardie, LJ., Zhang, R., Winter, H., Corley, DA., Panter, S., Risch, HA., Reid, BJ., Sargeant, I., Gammon, MD., Smart, H., Dhar, A., McMurtry, H., Ali, H., Liu, G., Casson, AG., Chow, W-H., Rutter, M., Tawil, A., Morris, D., Nwokolo, C., Isaacs, P., Rodgers, C., Ragunath, K., MacDonald, C., Haigh, C., Monk, D., Davies, G., Wajed, S., Johnston, D., Gibbons, M., Cullen, S., Church, N., Langley, R., Griffin, M., Alderson, D., Deloukas, P., Hunt, SE., Gray, E., Dronov, S., Potter, SC., Tashakkori-Ghanbaria, A., Anderson, M., Brooks, C., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Duncanson, A., Markus, HS., Mathew, CG., Palmer, CNA., Plomin, R., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, N., Trynka, G., Wijmenga, C., Cazier, J-B., Atherfold, P., Nicholson, AM., Gellatly, NL., Glancy, D., Cooper, SC., Cunningham, D., Lind, T., Hapeshi, J., Ferry, D., Rathbone, B., Brown, J., Love, S., Attwood, S., MacGregor, S., Watson, P., Sanders, S., Ek, W., Harrison, RF., Moayyedi, P., de Caestecker, J., Barr, H., Stupka, E., Vaughan, TL., Peltonen, L., Spencer, CCA., Tomlinson, I., Donnelly, P., Jankowski, JAZ., Esophageal Adenocarcinoma Genetics Consortium, and Wellcome Trust Case Control Consortium 2, , 2012. Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus. Nat Genet, v. 44
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Keller, MF., Saad, M., Bras, J., Bettella, F., Nicolaou, N., Simón-Sánchez, J., Mittag, F., Büchel, F., Sharma, M., Gibbs, JR., Schulte, C., Moskvina, V., Durr, A., Holmans, P., Kilarski, LL., Guerreiro, R., Hernandez, DG., Brice, A., Ylikotila, P., Stefánsson, H., Majamaa, K., Morris, HR., Williams, N., Gasser, T., Heutink, P., Wood, NW., Hardy, J., Martinez, M., Singleton, AB., Nalls, MA., International Parkinson's Disease Genomics Consortium (IPDGC), and Wellcome Trust Case Control Consortium 2 (WTCCC2), , 2012. Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum Mol Genet, v. 21
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Strange, A., Riley, BP., Spencer, CCA., Morris, DW., Pirinen, M., O'Dushlaine, CT., Su, Z., Maher, BS., Freeman, C., Cormican, P., Bellenguez, C., Kenny, EM., Band, G., Wormley, B., Donohoe, G., Dilthey, A., Moutsianas, L., Quinn, E., Edkins, S., Judge, R., Coleman, K., Hunt, S., Tropea, D., Roche, S., Cummings, L., Kelleher, E., McKeon, P., Dinan, T., McDonald, C., Murphy, KC., O'Callaghan, E., O'Neill, FA., Waddington, JL., Walsh, D., Giannoulatou, E., Langford, C., Deloukas, P., Gray, E., Dronov, S., Potter, S., Pearson, R., Vukcevic, D., Tashakkori-Ghanbaria, A., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Duncanson, A., Jankowski, J., Markus, HS., Mathew, CG., Palmer, CNA., Plomin, R., Rautanen, A., Sawcer, SJ., Trembath, RC., Viswanathan, AC., Wood, NW., Stone, J., Scolnick, E., Purcell, S., Sklar, P., Ripke, S., Walters, J., Owen, MJ., O'Donovan, MC., Peltonen, L., McVean, G., Kendler, KS., Gill, M., Donnelly, P. and Corvin, A., 2012. Genome-Wide Association Study Implicates HLA-C*01:02 as a Risk Factor at the Major Histocompatibility Complex Locus in Schizophrenia BIOLOGICAL PSYCHIATRY, v. 72
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Bevan, S., Traylor, M., Adib-Samii, P., Malik, R., Paul, NLM., Jackson, C., Farrall, M., Rothwell, PM., Sudlow, C., Dichgans, M. and Markus, HS., 2012. Genetic heritability of ischemic stroke and the contribution of previously reported candidate gene and genomewide associations Stroke, v. 43
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Tsoi, LC., Spain, SL., Knight, J., Ellinghaus, E., Stuart, PE., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, JE., Kang, HM., Allen, MH., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, AD., Smith, CH., Cork, MJ., Estivill, X., Bowcock, AM., Krueger, GG., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, FO., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, RD., Vukcevic, D., Spencer, CCA., Deloukas, P., Mrowietz, U., Schreiber, S., Weidinger, S., Koks, S., Kingo, K., Esko, T., Metspalu, A., Lim, HW., Voorhees, JJ., Weichenthal, M., Wichmann, HE., Chandran, V., Rosen, CF., Rahman, P., Gladman, DD., Griffiths, CEM., Reis, A., Kere, J., Collaborative Association Study of Psoriasis (CASP), , Genetic Analysis of Psoriasis Consortium, , Psoriasis Association Genetics Extension, , Wellcome Trust Case Control Consortium 2, , Nair, RP., Franke, A., Barker, JNWN., Abecasis, GR., Elder, JT. and Trembath, RC., 2012. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet, v. 44
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Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, RS., Gudnason, T., Jones, GT., Van Rij, AM., Eapen, DJ., Baas, AF., Tregouet, DA., Morange, PE., Emmerich, J., Lindblad, B., Gottster, A., Kiemeny, LA., Lindholt, JS., Sakalihasan, N., Ferrell, RE., Carey, DJ., Elmore, JR., Tsao, PS., Grarup, N., Jørgensen, T., Witte, DR., Hansen, T., Pedersen, O., Pola, R., Gaetani, E., Magnadottir, HB., Wijmenga, C., Tromp, G., Ronkainen, A., Ruigrok, YM., Blankensteijn, JD., Mueller, T., Wells, PS., Corral, J., Soria, JM., Souto, JC., Peden, JF., Jalilzadeh, S., Mayosi, BM., Keavney, B., Strawbridge, RJ., Sabater-Lleal, M., Gertow, K., Baldassarre, D., Nyyssnen, K., Rauramaa, R., Smit, AJ., Mannarino, E., Giral, P., Tremoli, E., De Faire, U., Humphries, SE., Hamsten, A., Haraldsdottir, V., Olafsson, I., Magnusson, MK., Samani, NJ., Levey, AI., Markus, HS., Kostulas, K., Dichgans, M., Berger, K., Kuhlenbumer, G., Ringelstein, EB., Stoll, M., Seedorf, U., Rothwell, PM., Powell, JT., Kuivaniemi, H., Onundarson, PT., Valdimarsson, E., Matthiasson, SE., Gudbjartsson, DF., Thorgeirsson, G., Quyyumi, AA., Watkins, H., Farrall, M., Thorsteinsdottir, U. and Stefansson, K., 2012. Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism Journal of the American College of Cardiology, v. 60
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Holliday, EG., Maguire, JM., Evans, TJ., Koblar, SA., Jannes, J., Sturm, JW., Hankey, GJ., Baker, R., Golledge, J., Parsons, MW., Malik, R., McEvoy, M., Biros, E., Lewis, MD., Lincz, LF., Peel, R., Oldmeadow, C., Smith, W., Moscato, P., Barlera, S., Bevan, S., Bis, JC., Boerwinkle, E., Boncoraglio, GB., Brott, TG., Brown, RD., Cheng, YC., Cole, JW., Cotlarciuc, I., Devan, WJ., Fornage, M., Furie, KL., Grétarsdóttir, S., Gschwendtner, A., Ikram, MA., Longstreth, WT., Meschia, JF., Mitchell, BD., Mosley, TH., Nalls, MA., Parati, EA., Psaty, BM., Sharma, P., Stefansson, K., Thorleifsson, G., Thorsteinsdottir, U., Traylor, M., Verhaaren, BFJ., Wiggins, KL., Worrall, BB., Sudlow, C., Rothwell, PM., Farrall, M., Dichgans, M., Rosand, J., Markus, HS., Scott, RJ., Levi, C. and Attia, J., 2012. Common variants at 6p21.1 are associated with large artery atherosclerotic stroke Nature Genetics, v. 44
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Kennedy, F., Lanfranconi, S., Hicks, C., Reid, J., Gompertz, P., Price, C., Kerry, S., Norris, J. and Markus, HS., 2012. Antiplatelets vs anticoagulation for dissection: CADISS nonrandomized arm and meta-analysis Neurology, v. 79
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Brookes, RL., Willis, TA., Patel, B., Morris, RG. and Markus, HS., 2012. Depressive symptoms as a predictor of quality of life in cerebral small vessel disease, acting independently of disability; a study in both sporadic small vessel disease and CADASIL. Int J Stroke,
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Gulli, G. and Markus, HS., 2012. The use of FAST and ABCD2 scores in posterior circulation, compared with anterior circulation, stroke and transient ischemic attack Journal of Neurology, Neurosurgery and Psychiatry, v. 83
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2011
Nitkunan, A., Lanfranconi, S., Charlton, RA., Barrick, TR. and Markus, HS., 2011. Brain atrophy and cerebral small vessel disease a prospective follow-up study Stroke, v. 42
Doi: http://doi.org/10.1161/STROKEAHA.110.594267
Bis, JC., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, GR., Schminke, U., Post, WS., Smith, AV., Cupples, LA., Markus, HS., Schmidt, R., Huffman, JE., Lehtimäki, T., Baumert, J., Münzel, T., Heckbert, SR., Dehghan, A., North, K., Oostra, B., Bevan, S., Stoegerer, E-M., Hayward, C., Raitakari, O., Meisinger, C., Schillert, A., Sanna, S., Völzke, H., Cheng, Y-C., Thorsson, B., Fox, CS., Rice, K., Rivadeneira, F., Nambi, V., Halperin, E., Petrovic, KE., Peltonen, L., Wichmann, HE., Schnabel, RB., Dörr, M., Parsa, A., Aspelund, T., Demissie, S., Kathiresan, S., Reilly, MP., Taylor, K., Uitterlinden, A., Couper, DJ., Sitzer, M., Kähönen, M., Illig, T., Wild, PS., Orru, M., Lüdemann, J., Shuldiner, AR., Eiriksdottir, G., White, CC., Rotter, JI., Hofman, A., Seissler, J., Zeller, T., Usala, G., Ernst, F., Launer, LJ., D'Agostino, RB., O'Leary, DH., Ballantyne, C., Thiery, J., Ziegler, A., Lakatta, EG., Chilukoti, RK., Harris, TB., Wolf, PA., Psaty, BM., Polak, JF., Li, X., Rathmann, W., Uda, M., Boerwinkle, E., Klopp, N., Schmidt, H., Wilson, JF., Viikari, J., Koenig, W., Blankenberg, S., Newman, AB., Witteman, J., Heiss, G., van Duijn, C., Scuteri, A., Homuth, G., Mitchell, BD., Gudnason, V. and O'Donnell, CJ., 2011. Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque Nature Genetics, v. 43
Doi: 10.1038/ng.920
Bevan, S. and Markus, HS., 2011. Genetics of common polygenic ischaemic stroke: Current understanding and future challenges Stroke Research and Treatment,
Doi: http://doi.org/10.4061/2011/179061
Topakian, R., King, A., Kwon, SU., Schaafsma, A., Shipley, M. and Markus, HS., 2011. Ultrasonic plaque echolucency and emboli signals predict stroke in asymptomatic carotid stenosis NEUROLOGY, v. 77
King, A., Shipley, M., Markus, H. and Investigators, ACES., 2011. Optimizing protocols for risk prediction in asymptomatic carotid stenosis using embolic signal detection: the Asymptomatic Carotid Emboli Study. Stroke, v. 42
Doi: http://doi.org/10.1161/STROKEAHA.111.622514
Markus, HS., McCollum, C., Imray, C., Goulder, MA., Gilbert, J. and King, A., 2011. The von willebrand inhibitor ARC1779 reduces cerebral embolization after carotid endarterectomy: A randomized trial Stroke, v. 42
Doi: http://doi.org/10.1161/STROKEAHA.111.616649
GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group, , Wellcome Trust Case Control Consortium 2, , Zhou, K., Bellenguez, C., Spencer, CCA., Bennett, AJ., Coleman, RL., Tavendale, R., Hawley, SA., Donnelly, LA., Schofield, C., Groves, CJ., Burch, L., Carr, F., Strange, A., Freeman, C., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Craddock, N., Deloukas, P., Dronov, S., Duncanson, A., Edkins, S., Gray, E., Hunt, S., Jankowski, J., Langford, C., Markus, HS., Mathew, CG., Plomin, R., Rautanen, A., Sawcer, SJ., Samani, NJ., Trembath, R., Viswanathan, AC., Wood, NW., MAGIC investigators, , Harries, LW., Hattersley, AT., Doney, ASF., Colhoun, H., Morris, AD., Sutherland, C., Hardie, DG., Peltonen, L., McCarthy, MI., Holman, RR., Palmer, CNA., Donnelly, P. and Pearson, ER., 2011. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet, v. 43
Doi: http://doi.org/10.1038/ng.735
King, A., Serena, J., Bornstein, NM. and Markus, HS., 2011. Does impaired cerebrovascular reactivity predict stroke risk in asymptomatic carotid stenosis?: A prospective substudy of the asymptomatic carotid emboli study Stroke, v. 42
Doi: http://doi.org/10.1161/STROKEAHA.110.609057
UK Parkinson's Disease Consortium, , Wellcome Trust Case Control Consortium 2, , Spencer, CCA., Plagnol, V., Strange, A., Gardner, M., Paisan-Ruiz, C., Band, G., Barker, RA., Bellenguez, C., Bhatia, K., Blackburn, H., Blackwell, JM., Bramon, E., Brown, MA., Brown, MA., Burn, D., Casas, J-P., Chinnery, PF., Clarke, CE., Corvin, A., Craddock, N., Deloukas, P., Edkins, S., Evans, J., Freeman, C., Gray, E., Hardy, J., Hudson, G., Hunt, S., Jankowski, J., Langford, C., Lees, AJ., Markus, HS., Mathew, CG., McCarthy, MI., Morrison, KE., Palmer, CNA., Pearson, JP., Peltonen, L., Pirinen, M., Plomin, R., Potter, S., Rautanen, A., Sawcer, SJ., Su, Z., Trembath, RC., Viswanathan, AC., Williams, NW., Morris, HR., Donnelly, P. and Wood, NW., 2011. Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21. Hum Mol Genet, v. 20
Doi: http://doi.org/10.1093/hmg/ddq469
Bevan, S., Meidtner, K., Lorenz, M., Sitzer, M., Grant, PJ. and Markus, HS., 2011. Adiponectin level as a consequence of genetic variation, but not leptin level or leptin: adiponectin ratio, is a risk factor for carotid intima-media thickness. Stroke, v. 42
Doi: http://doi.org/10.1161/STROKEAHA.110.602375
Wong, KS., Chen, C., Fu, J., Chang, HM., Suwanwela, NC., Huang, YN., Han, Z., Tan, KS., Ratanakorn, D., Chollate, P., Zhao, Y., Koh, A., Hao, Q. and Markus, HS., 2011. Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial. Lancet Neurology, v. 9
Doi: http://doi.org/10.1016/S1474-4422(10)70060-0
King, A., Bath, PMW. and Markus, HS., 2011. Clopidogrel versus dipyridamole in addition to aspirin in reducing embolization detected with ambulatory transcranial Doppler: A randomized trial Stroke, v. 42
Doi: http://doi.org/10.1161/STROKEAHA.110.601807
Evans, DM., Spencer, CCA., Pointon, JJ., Su, Z., Harvey, D., Kochan, G., Oppermann, U., Dilthey, A., Pirinen, M., Stone, MA., Appleton, L., Moutsianas, L., Leslie, S., Wordsworth, T., Kenna, TJ., Karaderi, T., Thomas, GP., Ward, MM., Weisman, MH., Farrar, C., Bradbury, LA., Danoy, P., Inman, RD., Maksymowych, W., Gladman, D., Rahman, P., Spondyloarthritis Research Consortium of Canada (SPARCC), , Morgan, A., Marzo-Ortega, H., Bowness, P., Gaffney, K., Gaston, JSH., Smith, M., Bruges-Armas, J., Couto, A-R., Sorrentino, R., Paladini, F., Ferreira, MA., Xu, H., Liu, Y., Jiang, L., Lopez-Larrea, C., Díaz-Peña, R., López-Vázquez, A., Zayats, T., Band, G., Bellenguez, C., Blackburn, H., Blackwell, JM., Bramon, E., Bumpstead, SJ., Casas, JP., Corvin, A., Craddock, N., Deloukas, P., Dronov, S., Duncanson, A., Edkins, S., Freeman, C., Gillman, M., Gray, E., Gwilliam, R., Hammond, N., Hunt, SE., Jankowski, J., Jayakumar, A., Langford, C., Liddle, J., Markus, HS., Mathew, CG., McCann, OT., McCarthy, MI., Palmer, CNA., Peltonen, L., Plomin, R., Potter, SC., Rautanen, A., Ravindrarajah, R., Ricketts, M., Samani, N., Sawcer, SJ., Strange, A., Trembath, RC., Viswanathan, AC., Waller, M., Weston, P., Whittaker, P., Widaa, S., Wood, NW., McVean, G., Reveille, JD., Wordsworth, BP., Brown, MA., Donnelly, P., Australo-Anglo-American Spondyloarthritis Consortium (TASC), and Wellcome Trust Case Control Consortium 2 (WTCCC2), , 2011. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet, v. 43
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2010
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Carotid artery stenting compared with endarterectomy in patients with symptomatic carotid stenosis (International Carotid Stenting Study): an interim analysis of a randomised controlled trial LANCET, v. 375
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Debette, S. and Markus, HS., 2010. The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ, v. 341
Mackinnon, AD., Jerrard-Dunne, P., Porteous, L. and Markus, HS., 2010. Carotid intima-media thickness is greater but carotid plaque prevalence is lower in black compared with white subjects American Journal of Neuroradiology, v. 31
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Moynihan, B., Davis, D., Pereira, A., Cloud, G. and Markus, HS., 2010. Delivering regional thrombolysis via a hub-and-spoke model Journal of the Royal Society of Medicine, v. 103
Doi: http://doi.org/10.1258/jrsm.2010.090434
Robinson, TG., Potter, JF., Ford, GA., Bulpitt, CJ., Chernova, J., Jagger, C., James, MA., Knight, J., Markus, HS., Mistri, AK. and Poulter, NR., 2010. Effects of antihypertensive treatment after acute stroke in the Continue Or Stop post-Stroke Antihypertensives Collaborative Study (COSSACS): A prospective, randomised, open, blinded-endpoint trial The Lancet Neurology, v. 9
Doi: http://doi.org/10.1016/S1474-4422(10)70163-0
Barrick, TR., Charlton, RA., Clark, CA. and Markus, HS., 2010. White matter structural decline in normal ageing: A prospective longitudinal study using tract-based spatial statistics NeuroImage, v. 51
Doi: http://doi.org/10.1016/j.neuroimage.2010.02.033
Groves, RW., Liu, L., Dopping-Hepenstal, PJ., Markus, HS., Lovell, PA., Ozoemena, L., Lai-Cheong, JE., Gawler, J., Owaribe, K., Hashimoto, T., Mellerio, JE., Mee, JB. and McGrath, JA., 2010. A homozygous nonsense mutation within the dystonin gene coding for the coiled-coil domain of the epithelial isoform of BPAG1 underlies a new subtype of autosomal recessive epidermolysis bullosa simplex Journal of Investigative Dermatology, v. 130
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Charlton, RA., Barrick, TR., Lawes, INC., Markus, HS. and Morris, RG., 2010. White matter pathways associated with working memory in normal aging Cortex, v. 46
Doi: http://doi.org/10.1016/j.cortex.2009.07.005
Adib-Samii, P., Brice, G., Martin, RJ. and Markus, HS., 2010. Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: Study in 200 consecutively recruited individuals Stroke, v. 41
Doi: http://doi.org/10.1161/STROKEAHA.109.568402
Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium 2, , Strange, A., Capon, F., Spencer, CCA., Knight, J., Weale, ME., Allen, MH., Barton, A., Band, G., Bellenguez, C., Bergboer, JGM., Blackwell, JM., Bramon, E., Bumpstead, SJ., Casas, JP., Cork, MJ., Corvin, A., Deloukas, P., Dilthey, A., Duncanson, A., Edkins, S., Estivill, X., Fitzgerald, O., Freeman, C., Giardina, E., Gray, E., Hofer, A., Hüffmeier, U., Hunt, SE., Irvine, AD., Jankowski, J., Kirby, B., Langford, C., Lascorz, J., Leman, J., Leslie, S., Mallbris, L., Markus, HS., Mathew, CG., McLean, WHI., McManus, R., Mössner, R., Moutsianas, L., Naluai, AT., Nestle, FO., Novelli, G., Onoufriadis, A., Palmer, CNA., Perricone, C., Pirinen, M., Plomin, R., Potter, SC., Pujol, RM., Rautanen, A., Riveira-Munoz, E., Ryan, AW., Salmhofer, W., Samuelsson, L., Sawcer, SJ., Schalkwijk, J., Smith, CH., Ståhle, M., Su, Z., Tazi-Ahnini, R., Traupe, H., Viswanathan, AC., Warren, RB., Weger, W., Wolk, K., Wood, N., Worthington, J., Young, HS., Zeeuwen, PLJM., Hayday, A., Burden, AD., Griffiths, CEM., Kere, J., Reis, A., McVean, G., Evans, DM., Brown, MA., Barker, JN., Peltonen, L., Donnelly, P. and Trembath, RC., 2010. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet, v. 42
Doi: http://doi.org/10.1038/ng.694
Lamar, M., Charlton, RA., Morris, RG. and Markus, HS., 2010. The Impact of Subcortical White Matter Disease on Mood in Euthymic Older Adults: A Diffusion Tensor Imaging Study AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, v. 18
Doi: http://doi.org/10.1097/JGP.0b013e3181cabad1
Topakian, R., Barrick, TR., Howe, FA. and Markus, HS., 2010. Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis Journal of Neurology, Neurosurgery and Psychiatry, v. 81
Doi: http://doi.org/10.1136/jnnp.2009.172072
Markus, HS., King, A., Shipley, M., Topakian, R., Cullinane, M., Reihill, S., Bornstein, NM. and Schaafsma, A., 2010. Asymptomatic embolisation for prediction of stroke in the Asymptomatic Carotid Emboli Study (ACES): a prospective observational study. Lancet Neurol, v. 9
Doi: http://doi.org/10.1016/S1474-4422(10)70120-4
Charlton, RA., Landau, S., Schiavone, F., Barrick, TR., Clark, CA., Markus, HS. and Morris, RG., 2010. Up the garden path: A critique of Penke and Deary and further exploration concerning the Charlton et al. path analysis relating loss of white matter integrity to cognition in normal aging Neurobiology of Aging, v. 31
Doi: http://doi.org/10.1016/j.neurobiolaging.2009.12.011
Charlton, RA., Schiavone, F., Barrick, TR., Morris, RG. and Markus, HS., 2010. Diffusion tensor imaging detects age related white matter change over a 2 year follow-up which is associated with working memory decline Journal of Neurology, Neurosurgery and Psychiatry, v. 81
Doi: http://doi.org/10.1136/jnnp.2008.167288
2009
Hannesdottir, K., Nitkunan, A., Charlton, RA., Barrick, TR., MacGregor, GA. and Markus, HS., 2009. Cognitive impairment and white matter damage in hypertension: a pilot study. Acta Neurol Scand, v. 119
Doi: http://doi.org/10.1111/j.1600-0404.2008.01098.x
Schiavone, F., Charlton, RA., Barrick, TR., Morris, RG. and Markus, HS., 2009. Imaging Age-Related Cognitive Decline: A Comparison of Diffusion Tensor and Magnetization Transfer MRI JOURNAL OF MAGNETIC RESONANCE IMAGING, v. 29
Doi: http://doi.org/10.1002/jmri.21572
Khan, S., Rich, P., Clifton, A. and Markus, HS., 2009. Noninvasive detection of vertebral artery stenosis: A comparison of contrast-enhanced MR angiography, CT angiography, and ultrasound Stroke, v. 40
Doi: http://doi.org/10.1161/STROKEAHA.109.556035
Gudbjartsson, DF., Holm, H., Gretarsdottir, S., Thorleifsson, G., Walters, GB., Thorgeirsson, G., Gulcher, J., Mathiesen, EB., Njølstad, I., Nyrnes, A., Wilsgaard, T., Hald, EM., Hveem, K., Stoltenberg, C., Kucera, G., Stubblefield, T., Carter, S., Roden, D., Ng, MCY., Baum, L., So, WY., Wong, KS., Chan, JCN., Gieger, C., Wichmann, H-E., Gschwendtner, A., Dichgans, M., Kuhlenbäumer, G., Berger, K., Ringelstein, EB., Bevan, S., Markus, HS., Kostulas, K., Hillert, J., Sveinbjörnsdóttir, S., Valdimarsson, EM., Løchen, M-L., Ma, RCW., Darbar, D., Kong, A., Arnar, DO., Thorsteinsdottir, U. and Stefansson, K., 2009. A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke Nature Genetics, v. 41
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UK IBD Genetics Consortium, , Barrett, JC., Lee, JC., Lees, CW., Prescott, NJ., Anderson, CA., Phillips, A., Wesley, E., Parnell, K., Zhang, H., Drummond, H., Nimmo, ER., Massey, D., Blaszczyk, K., Elliott, T., Cotterill, L., Dallal, H., Lobo, AJ., Mowat, C., Sanderson, JD., Jewell, DP., Newman, WG., Edwards, C., Ahmad, T., Mansfield, JC., Satsangi, J., Parkes, M., Mathew, CG., Wellcome Trust Case Control Consortium 2, , Donnelly, P., Peltonen, L., Blackwell, JM., Bramon, E., Brown, MA., Casas, JP., Corvin, A., Craddock, N., Deloukas, P., Duncanson, A., Jankowski, J., Markus, HS., Mathew, CG., McCarthy, MI., Palmer, CNA., Plomin, R., Rautanen, A., Sawcer, SJ., Samani, N., Trembath, RC., Viswanathan, AC., Wood, N., Spencer, CCA., Barrett, JC., Bellenguez, C., Davison, D., Freeman, C., Strange, A., Donnelly, P., Langford, C., Hunt, SE., Edkins, S., Gwilliam, R., Blackburn, H., Bumpstead, SJ., Dronov, S., Gillman, M., Gray, E., Hammond, N., Jayakumar, A., McCann, OT., Liddle, J., Perez, ML., Potter, SC., Ravindrarajah, R., Ricketts, M., Waller, M., Weston, P., Widaa, S., Whittaker, P., Deloukas, P., Peltonen, L., Mathew, CG., Blackwell, JM., Brown, MA., Corvin, A., McCarthy, MI., Spencer, CCA., Attwood, AP., Stephens, J., Sambrook, J., Ouwehand, WH., McArdle, WL., Ring, SM. and Strachan, DP., 2009. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat Genet, v. 41
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Bevan, S., Lorenz, MW., Sitzer, M. and Markus, HS., 2009. Genetic Variation in the Leukotriene Pathway and Carotid Intima-Media Thickness Stroke, v. 40
Doi: 10.1161/strokeaha.108.525733
Gschwendtner, A., Bevan, S., Cole, JW., Plourde, A., Matarin, M., Ross-Adams, H., Meitinger, T., Wichmann, E., Mitchell, BD., Furie, K., Slowik, A., Rich, SS., Syme, PD., MacLeod, MJ., Meschia, JF., Rosand, J., Kittner, SJ., Markus, HS., Müller-Myhsok, B., Dichgans, M. and International Stroke Genetics Consortium, , 2009. Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke. Ann Neurol, v. 65
Doi: http://doi.org/10.1002/ana.21590
Ederle, J., Bonati, LH., Dobson, J., Featherstone, RL., Gaines, PA., Beard, JD., Venables, GS., Markus, HS., Clifton, A., Sandercock, P. and Brown, MM., 2009. Endovascular treatment with angioplasty or stenting versus endarterectomy in patients with carotid artery stenosis in the Carotid And Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial The Lancet Neurology, v. 8
Doi: http://doi.org/10.1016/S1474-4422(09)70228-5
Birns, J., Jarosz, J., Markus, HS. and Kalra, L., 2009. Cerebrovascular reactivity and dynamic autoregulation in ischaemic subcortical white matter disease Journal of Neurology, Neurosurgery and Psychiatry, v. 80
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Birns, J., Morris, R., Jarosz, J., Markus, HS. and Kalra, L., 2009. Hypertension-related cognitive decline: is the time right for intervention studies? Minerva Cardioangiol, v. 57
Bonati, LH., Ederle, J., McCabe, DJ., Dobson, J., Featherstone, RL., Gaines, PA., Beard, JD., Venables, GS., Markus, HS., Clifton, A., Sandercock, P. and Brown, MM., 2009. Long-term risk of carotid restenosis in patients randomly assigned to endovascular treatment or endarterectomy in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): long-term follow-up of a randomised trial The Lancet Neurology, v. 8
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Freilinger, T., Bevan, S., Ripke, S., Gschwendtner, A., Lichtner, P., Müller-Myhsok, B., Wichmann, H-E., Markus, HS., Meitinger, T. and Dichgans, M., 2009. Genetic variation in the lymphotoxin-alpha pathway and the risk of ischemic stroke in European populations. Stroke, v. 40
Doi: http://doi.org/10.1161/STROKEAHA.107.510800
Charlton, RA., Barrick, TR., Markus, HS. and Morris, RG., 2009. Theory of Mind Associations With Other Cognitive Functions and Brain Imaging in Normal Aging PSYCHOLOGY AND AGING, v. 24
Doi: http://doi.org/10.1037/a0015225
Debette, S., Metso, TM., Pezzini, A., Engelter, ST., Leys, D., Lyrer, P., Metso, AJ., Brandt, T., Kloss, M., Lichy, C., Hausser, I., Touzé, E., Markus, HS., Abboud, S., Caso, V., Bersano, A., Grau, A., Altintas, A., Amouyel, P., Tatlisumak, T., Dallongeville, J., Grond-Ginsbach, C., Pandolfo, M., Thijs, V., Metso, M., Tatlisumak, T., Bodenant, M., Leys, D., Ossou, P., Louillet, F., Mas, JL., Leder, S., Léger, A., Deltour, S., Crozier, S., Méresse, I., Samson, Y., Canaple, S., Godefroy, O., Lamy, C., Béjot, Y., Giroud, M., Decavel, P., Medeiros, E., Montiel, P., Moulin, T., Vuillier, F., Fievet, N., Bellengier, L., Deplanque, D., Libersa, C., Schilling, S., Montel, S., Rémy, C., Wiest, T., Werner, I., Arnold, ML., Dos Santos, M., Dichgans, M., Brandt, T., Thomas-Feles, C., Weber, R., Del Zotto, E., Giossi, A., Padovani, A., Ballabio, E., Beretta, S., Ferrarese, C., Sessa, M., Paolucci, S., Engelter, S., Fluri, F., Hatz, F., Gisler, D., Tiemessen, A. and Martin, JJ., 2009. CADISP-genetics: An International project searching for genetic risk factors of cervical artery dissections International Journal of Stroke, v. 4
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Debette, S., Bevan, S., Dartigues, JF., Sitzer, M., Lorenz, M., Ducimetière, P., Amouyel, P. and Markus, HS., 2009. Fractalkine receptor/ligand genetic variants and carotid intima-media thickness Stroke, v. 40
Doi: http://doi.org/10.1161/STROKEAHA.108.537159
Birns, J., Morris, R., Jarosz, J., Markus, H. and Kalra, L., 2009. The structural and functional consequences of diurnal variations in blood pressure in treated patients with hypertensive cerebrovascular disease Journal of Hypertension, v. 27
Doi: http://doi.org/10.1097/HJH.0b013e32832810d5
Nitkunan, A., Charlton, RA., Barrick, TR., Mcintyre, DJO., Howe, FA. and Markus, HS., 2009. Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease NMR in Biomedicine, v. 22
Doi: http://doi.org/10.1002/nbm.1322
2008
Kerry, S., Markus, H., Khong, T., Doshi, R., Conroy, R. and Oakeshott, P., 2008. Community based trial of home blood pressure monitoring with nurse-led telephone support in patients with stroke or transient ischaemic attack recently discharged from hospital Trials, v. 9
Doi: http://doi.org/10.1186/1745-6215-9-15
Hainsworth, AH. and Markus, HS., 2008. Do in vivo experimental models reflect human cerebral small vessel disease? A systematic review Journal of Cerebral Blood Flow and Metabolism, v. 28
Doi: http://doi.org/10.1038/jcbfm.2008.91
Khan, U., Crossley, C., Kalra, L., Rudd, A., Wolfe, CDA., Collinson, P. and Markus, HS., 2008. Homocysteine and Its Relationship to Stroke Subtypes in a UK Black Population The South London Ethnicity and Stroke Study STROKE, v. 39
Doi: http://doi.org/10.1161/STROKEAHA.107.513416
Charlton, RA., Landau, S., Schiavone, F., Barrick, TR., Clark, CA., Markus, HS. and Morris, RG., 2008. A structural equation modeling investigation of age-related variance in executive function and DTI measured white matter damage Neurobiology of Aging, v. 29
Doi: http://doi.org/10.1016/j.neurobiolaging.2007.03.017
Birns, J., Morris, R., Jarosz, J., Markus, H. and Kalra, L., 2008. Ethnic differences in the cerebrovascular impact of hypertension. Cerebrovasc Dis, v. 25
Doi: http://doi.org/10.1159/000121341
Menon, R., Kerry, S., Norris, JW. and Markus, HS., 2008. Treatment of cervical artery dissection: A systematic review and meta-analysis Journal of Neurology, Neurosurgery and Psychiatry, v. 79
Doi: http://doi.org/10.1136/jnnp.2007.138800
Bevan, S., Dichgans, M., Gschwendtner, A., Kuhlenbäumer, G., Ringelstein, EB. and Markus, HS., 2008. Variation in the PDE4D Gene and Ischemic Stroke Risk Stroke, v. 39
Doi: 10.1161/strokeaha.107.509992
Gretarsdottir, S., Thorleifsson, G., Manolescu, A., Styrkarsdottir, U., Helgadottir, A., Gschwendtner, A., Kostulas, K., Kuhlenbäumer, G., Bevan, S., Jonsdottir, T., Bjarnason, H., Saemundsdottir, J., Palsson, S., Arnar, DO., Holm, H., Thorgeirsson, G., Valdimarsson, EM., Sveinbjörnsdottir, S., Gieger, C., Berger, K., Wichmann, HE., Hillert, J., Markus, H., Gulcher, JR., Ringelstein, EB., Kong, A., Dichgans, M., Gudbjartsson, DF., Thorsteinsdottir, U. and Stefansson, K., 2008. Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke Annals of Neurology, v. 64
Doi: http://doi.org/10.1002/ana.21480
Bevan, S., Dichgans, M., Wiechmann, HE., Gschwendtner, A., Meitinger, T. and Markus, HS., 2008. Genetic Variation in Members of the Leukotriene Biosynthesis Pathway Confer an Increased Risk of Ischemic Stroke Stroke, v. 39
Doi: 10.1161/strokeaha.107.491969
Nitkunan, A., Barrick, TR., Charlton, RA., Clark, CA. and Markus, HS., 2008. Multimodal MRI in cerebral small vessel disease: Its relationship with cognition and sensitivity to change over time Stroke, v. 39
Doi: http://doi.org/10.1161/STROKEAHA.107.507475
Menon, RK., Markus, HS. and Norris, JW., 2008. Results of a UK questionnaire of diagnosis and treatment in cervical artery dissection Journal of Neurology, Neurosurgery and Psychiatry, v. 79
Doi: http://doi.org/10.1136/jnnp.2007.127639
Dichgans, M., Markus, HS., Salloway, S., Verkkoniemi, A., Moline, M., Wang, Q., Posner, H. and Chabriat, HS., 2008. Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL The Lancet Neurology, v. 7
Doi: http://doi.org/10.1016/S1474-4422(08)70046-2
Nitkunan, A., Charlton, RA., McIntyre, DJO., Barrick, TR., Howe, FA. and Markus, HS., 2008. Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease Magnetic Resonance in Medicine, v. 59
Doi: http://doi.org/10.1002/mrm.21461
2007
Nowell, J., Wilton, E., Markus, H. and Jahangiri, M., 2007. Antithrombotic therapy following bioprosthetic aortic valve replacement European Journal of Cardio-thoracic Surgery, v. 31
Doi: http://doi.org/10.1016/j.ejcts.2006.12.017
Rangi, PS., Markus, HS., Punter, MNM. and Clifton, A., 2007. The use of intraoperative monitoring and treatment of symptomatic microemboli in carotid artery stenting: case report and discussion NEURORADIOLOGY, v. 49
Doi: http://doi.org/10.1007/s00234-006-0172-2
Markus, HS., Khan, U., Birns, J., Evans, A., Kalra, L., Rudd, AG., Wolfe, CDA. and Jerrard-Dunne, P., 2007. Differences in stroke subtypes between black and white patients with stroke - The south London ethnicity and stroke study CIRCULATION, v. 116
Doi: http://doi.org/10.1161/CIRCULATIONAHA.107.699785
Motallebzadeh, R., Bland, JM., Markus, HS., Kaski, JC. and Jahangiri, M., 2007. Neurocognitive function and cerebral emboli: randomized study of on-pump versus off-pump coronary artery bypass surgery. Ann Thorac Surg, v. 83
Doi: http://doi.org/10.1016/j.athoracsur.2006.09.024
Khan, S., Cloud, GC., Kerry, S. and Markus, HS., 2007. Imaging of vertebral artery stenosis: A systematic review Journal of Neurology, Neurosurgery and Psychiatry, v. 78
Doi: http://doi.org/10.1136/jnnp.2006.111716
Armstrong, C., Abilleira, S., Sitzer, M., Markus, HS. and Bevan, S., 2007. Polymorphisms in MMP family and TIMP genes and carotid artery intima-media thickness Stroke, v. 38
Doi: http://doi.org/10.1161/STROKEAHA.107.491696
Markus, H., 2007. Antiplatelet therapy vs. anticoagulation in cervical artery dissection; Rationale and design of the Cervical Artery Dissection in Stroke Study (CADISS) International Journal of Stroke, v. 2
Doi: http://doi.org/10.1111/j.1747-4949.2007.00165.x
Lorenz, MW., Markus, HS., Bots, ML., Rosvall, M. and Sitzer, M., 2007. Prediction of clinical cardiovascular events with carotid intima-media thickness: A systematic review and meta-analysis Circulation, v. 115
Doi: http://doi.org/10.1161/CIRCULATIONAHA.106.628875
Gormley, K., Bevan, S. and Markus, HS., 2007. Polymorphisms in genes of the renin-angiotensin system and cerebral small vessel disease Cerebrovascular Diseases, v. 23
Doi: http://doi.org/10.1159/000097052
Markus, HS., 2007. Mild cognitive impairment after lacunar infarction: Voxel-based morphometry and neuropsychological assessment Cerebrovascular Diseases, v. 23
Doi: http://doi.org/10.1159/000099129
Lorenz, MW., Sitzer, M., Markus, HS., Bots, ML. and Rosvall, M., 2007. Prediction of clinical cardiovascular events with carotid intima-media thickness: A systematic review and meta-analysis - Response CIRCULATION, v. 116
Doi: http://doi.org/10.1161/CIRCULATIONAHA.107.707067
Khan, U., Bevan, S. and Markus, HS., 2007. NADPH oxidase polymorphisms in cerebral small vessel disease Cerebrovascular Diseases, v. 24
Doi: http://doi.org/10.1159/000103615
McIntyre, DJO., Charlton, RA., Markus, HS. and Howe, FA., 2007. Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain Journal of Magnetic Resonance Imaging, v. 26
Doi: http://doi.org/10.1002/jmri.21198
Charlton, RA., McIntyre, DJO., Howe, FA., Morris, RG. and Markus, HS., 2007. The relationship between white matter brain metabolites and cognition in normal aging: The GENIE study BRAIN RESEARCH, v. 1164
Doi: http://doi.org/10.1016/j.brainres.2007.06.027
Khan, U., Porteous, L., Hassan, A. and Markus, HS., 2007. Risk factor profile of cerebral small vessel disease and its subtypes Journal of Neurology, Neurosurgery and Psychiatry, v. 78
Doi: http://doi.org/10.1136/jnnp.2006.103549
Lorenz, MW., Karbstein, P., Markus, HS. and Sitzer, M., 2007. High-sensitivity C-reactive protein is not associated with carotid intima-media progression - The carotid atherosclerosis progression study STROKE, v. 38
Doi: http://doi.org/10.1161/STROKEAHA.106.476135
Dikos, G., Marcus, HS. and Papadatos, MP., 2007. Old ideas may still be new: A system identification approach to tanker freight modelling Systems Research and Behavioral Science, v. 24
Doi: http://doi.org/10.1002/sres.787
Labrum, R., Bevan, S., Sitzer, M., Lorenz, M. and Markus, HS., 2007. Toll receptor polymorphisms and carotid artery intima-media thickness Stroke, v. 38
Doi: http://doi.org/10.1161/01.STR.0000260184.85257.2b
2006
Dikos, G., Marcus, HS., Papadatos, MP. and Papakonstantinou, V., 2006. Niver lines: A system-dynamics approach to tanker freight modeling Interfaces, v. 36
Doi: http://doi.org/10.1287/inte.1060.0218
Markus, HS., 2006. Can microemboli on transcranial Doppler identify patients at increased stroke risk? Commentary Nature Clinical Practice Cardiovascular Medicine, v. 3
Doi: http://doi.org/10.1038/ncpcardio0533
Dittrich, R., Ritter, MA., Kaps, M., Siebler, M., Lees, K., Larrue, V., Nabavi, DG., Ringelstein, EB., Markus, HS. and Droste, DW., 2006. The use of embolic signal detection in multicenter trials to evaluate antiplatelet efficacy: Signal analysis and quality control mechanisms in the CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic carotid Stenosis) trial Stroke, v. 37
Doi: http://doi.org/10.1161/01.STR.0000209331.39894.3d
Markus, HS. and Punter, M., 2006. Embolus detection and differentiation using multifrequency transcranial Doppler - Response STROKE, v. 37
Armstrong, CA., Bevan, SN., Gormley, KT., Markus, HS. and Koblar, SA., 2006. Tissue plasminogen activator -7351C/T polymorphism and lacunar stroke [1] Stroke, v. 37
Doi: http://doi.org/10.1161/01.STR.0000199663.64894.4f
Motallebzadeh, R., Bland, JM., Markus, HS., Kaski, JC. and Jahangiri, M., 2006. Health-related quality of life outcome after on-pump versus off-pump coronary artery bypass graft surgery: a prospective randomized study. Ann Thorac Surg, v. 82
Doi: http://doi.org/10.1016/j.athoracsur.2006.03.081
Charlton, RA., Barrick, TR., McIntyre, DJ., Shen, Y., O'Sullivan, M., Howe, FA., Clark, CA., Morris, RG. and Markus, HS., 2006. White matter damage on diffusion tensor imaging correlates with age-related cognitive decline Neurology, v. 66
Doi: http://doi.org/10.1212/01.wnl.0000194256.15247.83
Lorenz, MW., von Kegler, S., Steinmetz, H., Markus, HS. and Sitzer, M., 2006. Carotid intima-media thickening indicates a higher vascular risk across a wide age range: prospective data from the Carotid Atherosclerosis Progression Study (CAPS). Stroke, v. 37
Doi: http://doi.org/10.1161/01.STR.0000196964.24024.ea
Masdeu, JC., Irimia, P., Asenbaum, S., Bogousslavsky, J., Brainin, M., Chabriat, H., Herholz, K., Markus, HS., Martínez-Vila, E., Niederkorn, K., Schellinger, PD. and Seitz, RJ., 2006. EFNS guideline on neuroimaging in acute stroke. Report of an EFNS task force European Journal of Neurology, v. 13
Doi: http://doi.org/10.1111/j.1468-1331.2006.01507.x
Abilleira, S., Bevan, S. and Markus, HS., 2006. The role of genetic variants of matrix metalloproteinases in coronary and carotid atherosclerosis Journal of Medical Genetics, v. 43
Doi: http://doi.org/10.1136/jmg.2006.040808
Markus, HS., Labrum, R., Bevan, S., Reindl, M., Egger, G., Wiedermann, CJ., Xu, Q., Kiechl, S. and Willeit, J., 2006. Genetic and acquired inflammatory conditions are synergistically associated with early carotid atherosclerosis Stroke, v. 37
Doi: http://doi.org/10.1161/01.STR.0000236637.72124.3f
Nitkunan, A., McIntyre, DJO., Barrick, TR., O'Sullivan, M., Shen, Y., Clark, CA., Howe, FA. and Markus, HS., 2006. Correlations between MRS and DTI in cerebral small vessel disease NMR in Biomedicine, v. 19
Doi: http://doi.org/10.1002/nbm.1052
2005
Markus, HS., Hunt, B., Palmer, K., Enzinger, C., Schmidt, H. and Schmidt, R., 2005. Markers of endothelial and hemostatic activation and progression of cerebral white matter hyperintensities: Longitudinal results of the Austrian Stroke Prevention Study Stroke, v. 36
Doi: http://doi.org/10.1161/01.STR.0000169924.60783.d4
Bess, HD., Marcus, HS. and Valdez, ME., 2005. Government transportation statistics: Use with caution: A research note TRANSPORTATION JOURNAL, v. 44
Markus, HS., Droste, DW., Kaps, M., Larrue, V., Lees, KR., Siebler, M. and Ringelstein, EB., 2005. Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: The clopidogrel and aspirin for reduction of emboli in symptomatic carotid stenosis (CARESS) trial Circulation, v. 111
Doi: http://doi.org/10.1161/01.CIR.0000163561.90680.1C
Bevan, S., Porteous, L., Sitzer, M. and Markus, HS., 2005. Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis Stroke, v. 36
Doi: http://doi.org/10.1161/01.STR.0000162713.06519.41
O'Sullivan, M., Barrick, TR., Morris, RG., Clark, CA. and Markus, HS., 2005. Damage within a network of white matter regions underlies executive dysfunction in CADASIL Neurology, v. 65
Doi: http://doi.org/10.1212/01.wnl.0000184480.07394.fb
Pomeroy, VM., Clark, CA., Miller, JSG., Baron, JC., Markus, HS. and Tallis, RC., 2005. The potential for utilizing the "mirror neurone system" to enhance recovery of the severely affected upper limb early after stroke: A review and hypothesis NEUROREHABILITATION AND NEURAL REPAIR, v. 19
Doi: http://doi.org/10.1177/1545968304274351
Markus, HS., Droste, DW., Droste, DW., Ringelstein, EB., Kaps, M., Larrue, V., Lees, KR. and Siebler, M., 2005. id stenosis (CARESS) Trial" - To the editor - Response ... CIRCULATION, v. 112
Singhal, S., Rich, P. and Markus, HS., 2005. The spatial distribution of MR imaging abnormalities in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy and their relationship to age and clinical features American Journal of Neuroradiology, v. 26
Singhal, S. and Markus, HS., 2005. Cerebrovascular reactivity and dynamic autoregulation in nondemented patients with CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) Journal of Neurology, v. 252
Doi: http://doi.org/10.1007/s00415-005-0624-3
Markus, HS. and MacKinnon, A., 2005. Transcranial doppler and carotid artery disease strokes: More than just risk stratification - Response STROKE, v. 36
Hassan, A. and Markus, HS., 2005. Practicalities of genetic studies in human stroke. Methods in molecular medicine, v. 104
Markus, HS., Droste, DW., Ringelstein, EB., Kaps, M., Larrue, V., Lees, KR. and Siebler, M., 2005. Response [3] Circulation, v. 112
Doi: http://doi.org/10.1161/CIRCULATION.AHA.105.560755
O'Sullivan, M., Morris, RG. and Markus, HS., 2005. Brief cognitive assessment for patients with cerebral small vessel disease Journal of Neurology, Neurosurgery and Psychiatry, v. 76
Doi: http://doi.org/10.1136/jnnp.2004.045963
2004
O'Sullivan, M., Morris, RG., Huckstep, B., Jones, DK., Williams, SCR. and Markus, HS., 2004. Diffusion tensor MRI correlates with executive dysfunction in patients with ischaemic leukoaraiosis Journal of Neurology, Neurosurgery and Psychiatry, v. 75
Doi: http://doi.org/10.1136/jnnp.2003.014910
Jerrard-Dunne, P., Sitzer, M., Risley, P., Buehler, A., Von Kegler, S. and Markus, HS., 2004. Inflammatory gene load is associated with enhanced inflammation and early carotid atherosclerosis in smokers Stroke, v. 35
Doi: http://doi.org/10.1161/01.STR.0000144681.46696.b3
Singhal, S., Bevan, S., Barrick, T., Rich, P. and Markus, HS., 2004. The influence of genetic and cardiovascular risk factors on the CADASIL phenotype Brain, v. 127
Doi: http://doi.org/10.1093/brain/awh223
Mackinnon, AD., Jerrard-Dunne, P., Sitzer, M., Buehler, A., Von Kegler, S. and Markus, HS., 2004. Rates and determinants of site-specific progression of carotid artery intima-media thickness: The carotid atherosclerosis progression study Stroke, v. 35
Doi: http://doi.org/10.1161/01.STR.0000136720.21095.f3
Hassan, A., Gormley, K., O'Sullivan, M., Knight, J., Sham, P., Vallance, P., Bamford, J. and Markus, H., 2004. Endothelial Nitric Oxide Gene Haplotypes and Risk of Cerebral Small-Vessel Disease Stroke, v. 35
Doi: http://doi.org/10.1161/01.STR.0000117238.75736.53
Schmidt, R., Scheltens, P., Erkinjuntti, T., Pantoni, L., Markus, HS., Wallin, A., Barkhof, F. and Fazekas, F., 2004. White matter lesion progression: A surrogate endpoint for trials in cerebral small-vessel disease Neurology, v. 63
Doi: http://doi.org/10.1212/01.WNL.0000132635.75819.E5
Hassan, A., Hunt, BJ., O'Sullivan, M., Bell, R., D'Souza, R., Jeffery, S., Bamford, JM. and Markus, HS., 2004. Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction Brain, v. 127
Doi: http://doi.org/10.1093/brain/awh023
Aydin, N., Marvasti, F. and Markus, HS., 2004. Embolic Doppler ultrasound signal detection using discrete wavelet transform IEEE Transactions on Information Technology in Biomedicine, v. 8
Doi: http://doi.org/10.1109/TITB.2004.828882
Sidhu, JS., Kaposzta, Z., Markus, HS. and Kaski, JC., 2004. Effect of Rosiglitazone on Common Carotid Intima-Media Thickness Progression in Coronary Artery Disease Patients Without Diabetes Mellitus Arteriosclerosis, Thrombosis, and Vascular Biology, v. 24
Doi: http://doi.org/10.1161/01.ATV.0000124890.40436.77
Hussain, MB., Singhal, S., Markus, HS. and Singer, DRJ., 2004. Abnormal Vasoconstrictor Responses to Angiotensin II and Noradrenaline in Isolated Small Arteries from Patients with Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) Stroke, v. 35
Doi: http://doi.org/10.1161/01.STR.0000120730.54282.A0
Markus, HS., 2004. Variations in care and outcome in the first year after stroke: A Western and Central European perspective Journal of Neurology, Neurosurgery and Psychiatry, v. 75
Doi: http://doi.org/10.1136/jnnp.2004.048157
2003
Risley, P., Jerrard-Dunne, P., Sitzer, M., Buehler, A., Von Kegler, S. and Markus, HS., 2003. Promoter polymorphism in the endotoxin receptor (CD14) is associated with increased carotid atherosclerosis only in smokers: The Carotid Atherosclerosis Progression Study (CAPS) Stroke, v. 34
Doi: http://doi.org/10.1161/01.STR.0000055941.61801.5A
Hassan, A., Hunt, BJ., O'Sullivan, M., Parmar, K., Bamford, JM., Briley, D., Brown, MM., Thomas, DJ. and Markus, HS., 2003. Markers of endothelial dysfunction in lacunar infarction and ischaemic leukoaraiosis Brain, v. 126
Doi: http://doi.org/10.1093/brain/awg040
Jerrard-Dunne, P., Sitzer, M., Risley, P., Steckel, DA., Buehler, A., Von Kegler, S. and Markus, HS., 2003. Interleukin-6 promoter polymorphism modulates the effects of heavy alcohol consumption on early carotid artery atherosclerosis: The carotid atherosclerosis progression study (CAPS) Stroke, v. 34
Doi: http://doi.org/10.1161/01.STR.0000053849.09308.B2
Schon, F., Martin, RJ., Prevett, M., Clough, C., Enevoldson, TP. and Markus, HS., 2003. "CADASIL coma": an underdiagnosed acute encephalopathy JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 74
Doi: http://doi.org/10.1136/jnnp.74.2.249
Jerrard-Dunne, P., Evans, A., McGovern, R., Hajat, C., Kalra, L., Rudd, AG., Wolfe, CD. and Markus, HS., 2003. Ethnic differences in markers of thrombophilia implications for the investigation of ischemic stroke in multiethnic populations: The south London ethnicity and stroke study Stroke, v. 34
Doi: http://doi.org/10.1161/01.STR.0000083049.65008.5F
Jerrard-Dunne, P., Markus, HS., Steckel, DA., Buehler, A., von Kegler, S. and Sitzer, M., 2003. Early carotid atherosclerosis and family history of vascular disease: specific effects on arterial sites have implications for genetic studies. Arterioscler Thromb Vasc Biol, v. 23
Dong, Y., Hassan, A., Zhang, Z., Huber, D., Dalageorgou, C. and Markus, HS., 2003. Yield of screening for CADASIL mutations in lacunar stroke and leukoaraiosis Stroke, v. 34
Doi: http://doi.org/10.1161/01.STR.0000048162.16852.88
O'Sullivan, M., Rich, PM., Barrick, TR., Clark, CA. and Markus, HS., 2003. Frequency of subclinical lacunar infarcts in ischemic leukoaraiosis and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy American Journal of Neuroradiology, v. 24
Cloud, GC. and Markus, HS., 2003. Diagnosis and management of vertebral artery stenosis QJM: An International Journal of Medicine, v. 96
Doi: 10.1093/qjmed/hcg003
Cloud, GC. and Markus, HS., 2003. Diagnosis and management of vertebral artery stenosis. QJM, v. 96
Cloud, GC., Crawley, F., Clifton, A., McCabe, DJH., Brown, MM. and Markus, HS., 2003. Vertebral artery origin angioplasty and primary stenting: Safety and restenosis rates in a prospective series Journal of Neurology Neurosurgery and Psychiatry, v. 74
Doi: http://doi.org/10.1136/jnnp.74.5.586
Sitzer, M., Puac, D., Buehler, A., Steckel, DA., Von Kegler, S., Markus, HS. and Steinmetz, H., 2003. Internal carotid artery angle of origin: A novel risk factor for early carotid atherosclerosis Stroke, v. 34
Doi: http://doi.org/10.1161/01.STR.0000060895.38298.C4
2002
Kaposzta, Z., Clifton, A., Molloy, J., Martin, JF. and Markus, HS., 2002. <i>S</i>-nitrosoglutathione reduces asymptomatic embolization after carotid angioplasty CIRCULATION, v. 106
Doi: 10.1161/01.CIR.0000041251.07332.28
Markus, HS., Martin, RJ., Simpson, MA., Dong, YB., Ali, N., Crosby, AH. and Powell, JF., 2002. Diagnostic strategies in CADASIL NEUROLOGY, v. 59
Doi: http://doi.org/10.1212/WNL.59.8.1134
Cullinane, M., Kaposzta, Z., Reihill, S. and Markus, HS., 2002. Online automated detection of cerebral embolic signals from a variety of embolic sources Ultrasound in Medicine and Biology, v. 28
Doi: http://doi.org/10.1016/S0301-5629(02)00615-4
O'Sullivan, M., Lythgoe, DJ., Pereira, AC., Summers, PE., Jarosz, JM., Williams, SCR. and Markus, HS., 2002. Patterns of cerebral blood flow reduction in patients with ischemic leukoaraiosis NEUROLOGY, v. 59
Doi: http://doi.org/10.1212/WNL.59.3.321
O Sullivan, M., Rich, PM., Barrick, TR., Clark, CA. and Markus, HS., 2002. Detection of asymptomatic lacunar infarcts with diffusion weighted MRI: A potential surrogate marker of disease activity in ischaemic leukoaraiosis and CADASIL JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 73
Tinkler, K., Cullinane, M., Kaposzta, Z. and Markus, HS., 2002. Asymptomatic embolisation in non-valvular atrial fibrillation and its relationship to anticoagulation therapy European Journal of Ultrasound, v. 15
Doi: http://doi.org/10.1016/S0929-8266(01)00169-0
Hassan, A., Sham, PC. and Markus, HS., 2002. Planning genetic studies in human stroke: Sample size estimates based on family history data Neurology, v. 58
Doi: http://doi.org/10.1212/WNL.58.10.1483
Sitzer, M., Markus, HS., Mendall, MA., Liehr, R., Knorr, U. and Steinmetz, H., 2002. C-reactive protein and carotid intimal medial thickness in a community population. J Cardiovasc Risk, v. 9
Markus, HS., Risley, P., Mendall, MA., Steinmetz, H. and Sitzer, M., 2002. Helicobacter pylori infection, the cytotoxin gene A strain, and carotid artery intima-media thickness European Journal of Cardiovascular Prevention & Rehabilitation, v. 9
Doi: http://doi.org/10.1177/174182670200900101
2001
O'Sullivan, M., Jones, DK., Summers, PE., Morris, RG., Williams, SCR. and Markus, HS., 2001. Evidence for cortical "disconnection" as a mechanism of age-related cognitive decline Neurology, v. 57
Doi: http://doi.org/10.1212/WNL.57.4.632
Lythgoe, D., Simmons, A., Pereira, A., Cullinane, M., Williams, S. and Markus, HS., 2001. Magnetic resonance markers of ischaemia: Their correlation with vasodilatory reserve in patients with carotid artery stenosis and occlusion Journal of Neurology Neurosurgery and Psychiatry, v. 71
Doi: http://doi.org/10.1136/jnnp.71.1.58
Markus, H. and Cullinane, M., 2001. Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion Brain, v. 124
Doi: http://doi.org/10.1093/brain/124.3.457
Cullinane, M. and Markus, HS., 2001. Evaluation of a 1 MHz transducer for transcranial doppler ultrasound including embolic signal detection Ultrasound in Medicine and Biology, v. 27
Doi: http://doi.org/10.1016/S0301-5629(01)00369-6
Markus, H., 2001. The pathophysiology of stroke British Journal of Cardiology, v. 8
Kaposzta, Z., Baskerville, PA., Madge, D., Fraser, S., Martin, JF. and Markus, HS., 2001. L-arginine and <i>S</i>-nitrosoglutathione reduce embolization in humans CIRCULATION, v. 103
O'Sullivan, M., Jarosz, JM., Martin, RJ., Deasy, N., Powell, JF. and Markus, HS., 2001. MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL NEUROLOGY, v. 56
Doi: http://doi.org/10.1212/WNL.56.5.628
Markus, H. and Cullinane, M., 2001. Severely impaired cerebrovascular reactivity predicts stroke and TIA risk in patients with carotid artery stenosis and occlusion. Brain, v. 124
Kaposzta, Z., Baskerville, PA., Fraser, SCA., Madge, D., Martin, JF. and Markus, HS., 2001. S-nitrosoglutathione, a platelet specific nitric oxide donor, and L-arginine reduced embolisation post-carotid endarterectomy JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 70
Rose, SE., Chalk, JB., Griffin, MP., Janke, AL., Chen, F., McLachan, GJ., Peel, D., Zelaya, FO., Markus, HS., Jones, DK., Simmons, A., O'Sullivan, M., Jarosz, JM., Strugnell, W., Doddrell, DM. and Semple, J., 2001. MRI based diffusion and perfusion predictive model to estimate stroke evolution MAGN RESON IMAGING, v. 19
Martin, RJ., Powell, JF. and Markus, HS., 2001. Phenotypic heterogeneity in a United Kingdom CADASIL prevalence study JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 70
O Sullivan, M., Jones, DK., Summers, PE., Horsfield, MA., Williams, SCR., Jarosz, JM. and Markus, HS., 2001. Progressive frontal "disconnection": a mechanism for cognitive decline in normal aging JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 70
O Sullivan, M., Jarosz, JM., Deasy, N., Martin, RJ., Powell, J. and Markus, HS., 2001. Involvement of the temporal pole distinguishes CADASIL from ischaemic leukoaraiosis JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 70
O'Sullivan, M., Summers, PE., Jones, DK., Jarosz, JM., Williams, SCR. and Markus, HS., 2001. Normal-appearing white matter in ischemic leukoaraiosis: A diffusion tensor MRI study Neurology, v. 57
Doi: http://doi.org/10.1212/WNL.57.12.2307
Aydin, N. and Markus, HS., 2001. Time-scale analysis of quadrature Doppler ultrasound signals IEE Proceedings: Science, Measurement and Technology, v. 148
Doi: http://doi.org/10.1049/ip-smt:20010106
Hassan, A., Ali, N., Dong, Y., Carter, ND. and Markus, HS., 2001. Atrial natriuretic peptide gene G664A polymorphism and the risk of ischemic cerebrovascular disease Neurology, v. 57
Doi: http://doi.org/10.1212/WNL.57.9.1726
Aydin, N., Markus, HS. and Marvasti, F., 2001. Detection and estimation of embolic Doppler signals using discrete wavelet transform ICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings, v. 2
Doi: http://doi.org/10.1109/ICASSP.2001.941099
Risley, AFM., Stone, P., Markus, HS., Butland, BK., Strachan, DP., Elwood, PC. and Mendall, MA., 2001. Ischaemic heart disease and Cag a strains of Helicobacter pylori in the Caerphilly heart disease study Heart, v. 86
Hassan, A., Sham, P. and Markus, H., 2001. Modelling feasibility of genetic approaches to human stroke STROKE, v. 32
Markus, H., Kapozsta, Z., Ditrich, R., Wolfe, C., Ali, N., Powell, J., Mendell, M. and Cullinane, M., 2001. Increased common carotid intima-media thickness in UK African Caribbeans and its relation to chronic inflammation and vascular candidate gene polymorphisms STROKE, v. 32
Doi: http://doi.org/10.1161/hs1101.098152
Simpson, M., Ali, N., Dong, YB., Powell, J., Martin, R., Crosby, A. and Markus, H., 2001. Screening of British CADASIL families for NOTCH 3 mutations JOURNAL OF MEDICAL GENETICS, v. 38
2000
White, RP., Deane, C., Hindley, C., Bloomfield, PM., Cunningham, VJ., Vallance, P., Brooks, DJ. and Markus, HS., 2000. The effect of the nitric oxide donor glyceryl trinitrate on global and regional cerebral blood flow in man JOURNAL OF THE NEUROLOGICAL SCIENCES, v. 178
Doi: http://doi.org/10.1016/S0022-510X(00)00357-9
Markus, HS., 2000. Developing models of embolism for evaluating anti-thromboembolic therapies using doppler ultrasound embolic signal detection Acta Neurologica Taiwanica, v. 9
Markus, HS., Lythgoe, DJ., Ostegaard, L., O'Sullivan, M. and Williams, SCR., 2000. Reduced cerebral blood flow in white matter in ischaemic leukoaraiosis demonstrated using quantitative exogenous contrast based perfusion MRI JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 69
Doi: http://doi.org/10.1136/jnnp.69.1.48
Markus, H. and Kaposzta, Z., 2000. Clinical relevance of detecting asymptomatic embolic signals in acute stroke - Response STROKE, v. 31
Cullinane, M., Reid, G., Dittrich, R., Kaposzta, Z., Ackerstaff, R., Babikian, V., Droste, DW., Grossett, D., Siebler, M., Valton, L. and Markus, HS., 2000. Evaluation of new online automated embolic signal detection algorithm, including comparison with panel of international experts Stroke, v. 31
Doi: http://doi.org/10.1161/01.STR.31.6.1335
Markus, HS., 2000. Transcranial Doppler sonography in acute stroke - Reply JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 68
Markus, H., 2000. Asymptomatic embolization predicts stroke and TIA risk in patients with carotid artery stenosis - Response STROKE, v. 31
Lythgoe, DJ., Ostergaard, L., William, SC., Cluckie, A., Buxton-Thomas, M., Simmons, A. and Markus, HS., 2000. Quantitative perfusion imaging in carotid artery stenosis using dynamic susceptibility contrast-enhanced magnetic resonance imaging. Magn Reson Imaging, v. 18
Triantafyllou, C., Long, C., Suckling, J. and Markus, H., 2000. Multiscale registration of echo-planar with structural MR images using an automated 3D approach NeuroImage, v. 11
Doi: http://doi.org/10.1016/s1053-8119(00)91609-4
White, RP., Vallance, P. and Markus, HS., 2000. Effect of inhibition of nitric oxide synthase on dynamic cerebral autoregulation in humans CLINICAL SCIENCE, v. 99
Doi: http://doi.org/10.1042/CS20000064
Aydin, N. and Markus, HS., 2000. Directional wavelet transform in the context of complex quadrature Doppler signals IEEE Signal Processing Letters, v. 7
Doi: http://doi.org/10.1109/97.870680
1999
White, RP., Hindley, C., Bloomfield, PM., Cunningham, VJ., Vallance, P., Brooks, DJ. and Markus, HS., 1999. The effect of the nitric oxide synthase inhibitor L-NMMA on basal CBF and vasoneuronal coupling in man: a PET study JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, v. 19
Doi: http://doi.org/10.1097/00004647-199906000-00011
Ruigrok, Y., Cox, TCS. and Markus, HS., 1999. Positional vertebrobasilar transient ischaemic attacks treated with vertebral angioplasty CEREBROVASCULAR DISEASES, v. 9
Doi: http://doi.org/10.1159/000015949
Lythgoe, DJ., Williams, SCR., Cullinane, M. and Markus, HS., 1999. Mapping of cerebrovascular reactivity using bold magnetic resonance imaging MAGNETIC RESONANCE IMAGING, v. 17
Doi: http://doi.org/10.1016/S0730-725X(98)00211-2
Jones, DK., Lythgoe, D., Horsfield, MA., Simmons, A., Williams, SCR. and Markus, HS., 1999. Characterization of white matter damage in ischemic leukoaraiosis with diffusion tensor MRI STROKE, v. 30
Doi: http://doi.org/10.1161/01.STR.30.2.393
Al-Hamali, S., Baskerville, P., Fraser, S., Walters, H. and Markus, HS., 1999. Detection of distal emboli in patients with peripheral arterial stenosis before and after iliac angioplasty: A prospective study JOURNAL OF VASCULAR SURGERY, v. 29
Doi: http://doi.org/10.1016/S0741-5214(99)70387-3
Molloy, JE. and Markus, HS., 1999. Embolic signals predict risk of stroke and TIA in carotid artery stenosis STROKE, v. 30
Kaposzta, Z., Young, E., Bath, PMW. and Markus, HS., 1999. Clinical application of asymptomatic embolic signal detection in acute stroke - A prospective study STROKE, v. 30
Doi: http://doi.org/10.1161/01.STR.30.9.1814
Markus, HS., Sitzer, M., Carrington, D., Mendall, MA. and Steinmetz, H., 1999. <i>Chlamydia pneumoniae</i> infection and early asymptomatic carotid atherosclerosis CIRCULATION, v. 100
Doi: 10.1161/01.CIR.100.8.832
Markus, H., Cullinane, M. and Reid, G., 1999. Improved automated detection of embolic signals using a novel frequency filtering approach STROKE, v. 30
Doi: http://doi.org/10.1161/01.STR.30.8.1610
1998
Markus, HS., 1998. Homozygous C677T mutation of the 5,10 methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in Italian patients with a history of early-onset ischemic stroke - Response STROKE, v. 29
Ringelstein, EB., Droste, DW., Babikian, VL., Evans, DH., Grosset, DG., Kaps, M., Markus, HS., Russell, D. and Siebler, M., 1998. Consensus on microembolus detection by TCD: International consensus group on microembolus detection Stroke, v. 29
Doi: http://doi.org/10.1161/01.str.29.3.725
Ringelstein, EB., Droste, DW., Babikian, VL., Evans, DH., Grosset, DG., Kaps, M., Markus, HS., Russell, D. and Siebler, M., 1998. Consensus on microembolus detection by TCD STROKE, v. 29
Markus, HS., Kapadia, R. and Sherwood, RA., 1998. Lipoprotein (a) and ischaemic cerebrovascular disease - Authors' reply ANNALS OF CLINICAL BIOCHEMISTRY, v. 35
Doi: http://doi.org/10.1177/000456329803500230
White, RP., Deane, C., Vallance, P. and Markus, HS., 1998. Nitric oxide synthase inhibition in humans reduces cerebral blood flow but not the hyperemic response to hypercapnia STROKE, v. 29
Doi: http://doi.org/10.1161/01.STR.29.2.467
Markus, HS. and Hambley, H., 1998. Neurology and the blood: haematological abnormalities in ischaemic stroke JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 64
Doi: http://doi.org/10.1136/jnnp.64.2.150
Markus, HS. and Mendall, MA., 1998. <i>Helicobacter pylori</i> infection:: a risk factor for ischaemic cerebrovascular disease and carotid atheroma JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 64
Doi: 10.1136/jnnp.64.1.104
Molloy, J., Baskerville, PA., Fraser, SC., Martin, JF. and Markus, HS., 1998. S-nitrosoglutathione, a targeted NO donor, reduces cerebral embolisation in a new <i>in vivo</i> model STROKE, v. 29
Panerai, RB., White, RP., Markus, HS. and Evans, DH., 1998. Grading of cerebral dynamic autoregulation from spontaneous fluctuations in arterial blood pressure STROKE, v. 29
Doi: http://doi.org/10.1161/01.STR.29.11.2341
Molloy, J., Martin, JF., Baskerville, PA., Fraser, SCA. and Markus, HS., 1998. S-nitrosoglutathione reduces the rate of embolization in humans Circulation, v. 98
Doi: http://doi.org/10.1161/01.CIR.98.14.1372
Cullinane, M., Wainwright, R., Brown, A., Monaghan, M. and Markus, HS., 1998. Asymptomatic embolization in subjects with atrial fibrillation not taking anticoagulants - A prospective study STROKE, v. 29
Doi: http://doi.org/10.1161/01.STR.29.9.1810
Markus, HS., Ruigrok, Y., Ali, N. and Powell, JF., 1998. Endothelial nitric oxide synthase exon 7 polymorphism, ischemic cerebrovascular disease, and carotid atheroma STROKE, v. 29
Doi: http://doi.org/10.1161/01.STR.29.9.1908
Molloy, J., Khan, NH. and Markus, HS., 1998. Temporal variability of asymptomatic embolization in carotid artery stenosis and optimal recording protocols STROKE, v. 29
Doi: http://doi.org/10.1161/01.STR.29.6.1129
White, RP., Barnes, P. and Markus, HS., 1998. Symptomatic haemodynamically significant carotid occlusion treated by posterior circulation revascularization CEREBROVASCULAR DISEASES, v. 8
Doi: http://doi.org/10.1159/000015840
1997
Deane, CR. and Markus, HS., 1997. Colour velocity flow measurement: In vitro validation and application to human carotid arteries ULTRASOUND IN MEDICINE AND BIOLOGY, v. 23
Doi: http://doi.org/10.1016/S0301-5629(96)00224-4
Saxena, V., Markus, H., Swaminathan, S. and Mendall, MA., 1997. Hyperhomocysteinaemia, Helicobacter pylori, and coronary heart disease HEART, v. 78
Doi: http://doi.org/10.1136/hrt.78.5.524a
Ali, NS., Powell, J., Swaminathan, R. and Markus, HS., 1997. The relationship between MTHFR genotype, serum homocysteine and folate levels Biochemical Society Transactions, v. 25
Doi: http://doi.org/10.1042/bst025386s
Markus, HS., Ackerstaff, R., Babikian, V., Bladin, C., Droste, D., Grosset, D., Levi, C., Russell, D., Siebler, M. and Tegeler, C., 1997. Intercenter agreement in reading Doppler embolic signals - A multicenter international study STROKE, v. 28
Doi: http://doi.org/10.1161/01.STR.28.7.1307
Markus, HS., Kapadia, R. and Sherwood, RA., 1997. Relationship between lipoprotein (a) and both stroke and carotid atheroma ANNALS OF CLINICAL BIOCHEMISTRY, v. 34
Doi: http://doi.org/10.1177/000456329703400404
1996
Markus, HS., Zhang, YF. and Jeffery, S., 1996. Screening for the factor-V Arg 506 Gln mutation in patients with TIA and stroke CEREBROVASCULAR DISEASES, v. 6
Doi: http://doi.org/10.1159/000108053
Molloy, J. and Markus, HS., 1996. Multigated Doppler ultrasound in the detection of emboli in a flow model and embolic signals in patients STROKE, v. 27
Doi: http://doi.org/10.1161/01.STR.27.9.1548
Markus, H., Bland, JM., Rose, G., Sitzer, M. and Siebler, M., 1996. How good is intercenter agreement in the identification of embolic signals in carotid artery disease? STROKE, v. 27
Doi: http://doi.org/10.1161/01.STR.27.7.1249
Markus, HS., Clifton, A., Buckenham, T., Taylor, R. and Brown, MM., 1996. Improvement in cerebral hemodynamics after carotid angioplasty STROKE, v. 27
Doi: http://doi.org/10.1161/01.STR.27.4.612
Markus, HS., 1996. Angiotensin-converting enzyme gene and lacunar stroke - Response STROKE, v. 27
1995
MARKUS, H., 1995. MICROEMBOLIC SIGNALS IN PATIENTS REFERRED FOR ECHOCARDIOGRAPHY STROKE, v. 26
Markus, HS. and Tegeler, CH., 1995. Experimental aspects of high-intensity transient signals in the detection of emboli Journal of Clinical Ultrasound, v. 23
Doi: http://doi.org/10.1002/jcu.1870230204
MARKUS, H., BARLEY, J., LUNT, R., BLAND, M., JEFFERY, S., CARTER, N. and BROWN, M., 1995. ASSOCIATION OF DELETION POLYMORPHISM IN ANGIOTENSIN-CONVERTING ENZYME (ACE) GENE WITH SYMPTOMATIC CEREBROVASCULAR-DISEASE STROKE, v. 26
DUARTE, J., MARKUS, H. and HARRISON, M., 1995. CHANGES IN CEREBRAL BLOOD-FLOW AS MONITORED BY TRANSCRANIAL DOPPLER DURING VOLUNTARY HYPERVENTILATION AND THEIR EFFECT ON THE ELECTROENCEPHALOGRAM JOURNAL OF NEUROIMAGING, v. 5
Markus, HS., Thomson, ND. and Brown, MM., 1995. Asymptomatic cerebral embolic signals in symptomatic and asymptomatic carotid artery disease Brain, v. 118
Doi: http://doi.org/10.1093/brain/118.4.1005
MARKUS, HS., BARLEY, J., LUNT, R., BLAND, JM., JEFFERY, S., CARTER, ND. and BROWN, MM., 1995. ANGIOTENSIN-CONVERTING ENZYME GENE DELETION POLYMORPHISM - A NEW RISK FACTOR FOR LACUNAR STROKE BUT NOT CAROTID ATHEROMA STROKE, v. 26
Doi: http://doi.org/10.1161/01.STR.26.8.1329
Barley, J., Markus, H., Brown, M. and Carter, N., 1995. Lack of association between angiotensinogen polymorphism (M235T) and cerebrovascular disease and carotid atheroma Journal of Human Hypertension, v. 9
BUCKENHAM, T., CLIFTON, A., MARKUS, H., TAYLOR, R. and BROWN, M., 1995. CAROTID AND VERTEBRAL STENOSIS TREATED BY PERCUTANEOUS TRANSLUMINAL ANGIOPLASTY BRITISH JOURNAL OF SURGERY, v. 82
MARKUS, HS., LEES, AJ., LENNOX, G., MARSDEN, CD. and COSTA, DC., 1995. PATTERNS OF REGIONAL CEREBRAL BLOOD-FLOW IN CORTICOBASAL DEGENERATION STUDIED USING HMPAO SPECT - COMPARISON WITH PARKINSONS-DISEASE AND NORMAL CONTROLS MOVEMENT DISORDERS, v. 10
Doi: http://doi.org/10.1002/mds.870100208
1994
Markus, HS., Clifton, A., Buckenham, T. and Brown, MM., 1994. Carotid angioplasty detection of embolic signals during and after the procedure Stroke, v. 25
Doi: http://doi.org/10.1161/01.STR.25.12.2403
Markus, HS., Vallance, P. and Brown, MM., 1994. Differential effect of three cyclooxygenase inhibitors on human cerebral blood flow velocity and carbon dioxide reactivity Stroke, v. 25
Doi: http://doi.org/10.1161/01.STR.25.9.1760
Droste, DW., Markus, HS., Nassiri, D. and Brown, MM., 1994. The effect of velocity on the appearance of embolic signals studied in transcranial doppler models Stroke, v. 25
Doi: http://doi.org/10.1161/01.STR.25.5.986
DROSTE, D., MARKUS, H. and BROWN, M., 1994. THE EFFECT OF DIFFERENT SETTINGS OF ULTRASOUND PULSE AMPLITUDE, GAIN AND SAMPLE VOLUME ON THE APPEARANCE OF EMBOLI STUDIED IN A TRANSCRANIAL DOPPLER MODEL CEREBROVASCULAR DISEASES, v. 4
Doi: http://doi.org/10.1159/000108472
DROSTE, D., MARKUS, H., NASSIRI, D. and BROWN, M., 1994. THE EFFECT OF VELOCITY ON THE APPEARANCE OF EMBOLI STUDIED IN TRANSCRANIAL DOPPLER MODELS STROKE, v. 25
Brown, MM. and Markus, HS., 1994. Transcranial Doppler detection of asymptomatic cerebral microemboli Journal of Heart Valve Disease, v. 3
Markus, H., Loh, A. and Brown, MM., 1994. Detection of circulating cerebral emboli using Doppler ultrasound in a sheep model Journal of the Neurological Sciences, v. 122
Doi: http://doi.org/10.1016/0022-510X(94)90061-2
MARKUS, HS., COSTA, DC. and LEES, AJ., 1994. HMPAO SPECT IN PARKINSONS-DISEASE BEFORE AND AFTER LEVODOPA - CORRELATION WITH DOPAMINERGIC RESPONSIVENESS JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 57
Doi: http://doi.org/10.1136/jnnp.57.2.180
1993
Markus, HS., Droste, D. and Brown, MM., 1993. Ultrasonic detection of cerebral emboli in carotid stenosis. Lancet, v. 341
MARKUS, HS., MULLER, AF. and TOGHILL, PJ., 1993. SPLENIC FUNCTION, ASSESSED BY QUANTIFICATION OF ERYTHROCYTE-MEMBRANE PITS, IS NORMAL IN CHRONIC ACTIVE HEPATITIS AND PRIMARY BILIARY-CIRRHOSIS JOURNAL OF HEPATOLOGY, v. 18
Doi: http://doi.org/10.1016/S0168-8278(05)80017-0
Markus, H., Israel, D., Brown, MM., Loh, A., Buckenham, T. and Clifton, A., 1993. Microscopic air embolism during cerebral angiography and strategies for its avoidance The Lancet, v. 341
Doi: http://doi.org/10.1016/0140-6736(93)90561-T
MARKUS, H., VALLANCE, P. and BROWN, M., 1993. PROSTANGLANDINS DO NOT REGULATE CEREBRAL BLOOD-FLOW IN HUMANS - CLINICAL IMPORTANCE STROKE, v. 24
MARKUS, H., LOH, A. and BROWN, M., 1993. AIR-EMBOLISM DURING CEREBRAL-ANGIOGRAPHY AND STRATEGIES FOR ITS REMOVAL STROKE, v. 24
MARKUS, H., LOH, A., BROWN, M. and BRUCHER, R., 1993. INVIVO DETECTION OF CEREBRAL EMBOLI AND DISCRIMINATION FROM ARTIFACT STROKE, v. 24
MARKUS, HS., HARRISON, MJ. and ADISESHIAH, M., 1993. CAROTID ENDARTERECTOMY IMPROVES HEMODYNAMICS ON THE CONTRALATERAL SIDE - IMPLICATIONS FOR OPERATING CONTRALATERAL TO AN OCCLUDED CAROTID-ARTERY BRITISH JOURNAL OF SURGERY, v. 80
Doi: http://doi.org/10.1002/bjs.1800800212
MARKUS, HS., TOMKINS, AM. and STERN, GM., 1993. INCREASED PREVALENCE OF UNDERNUTRITION IN PARKINSONS-DISEASE AND ITS RELATIONSHIP TO CLINICAL-DISEASE PARAMETERS JOURNAL OF NEURAL TRANSMISSION-PARKINSONS DISEASE AND DEMENTIA SECTION, v. 5
Doi: http://doi.org/10.1007/BF02251202
Markus, HS. and Brown, MM., 1993. Differentiation between different pathological cerebral embolic materials using transcranial doppler in an in vitro model Stroke, v. 24
Doi: http://doi.org/10.1161/01.STR.24.1.1
Markus, H., Loh, A. and Brown, MM., 1993. Computerized detection of cerebral emboli and discrimination from artifact using doppler ultrasound Stroke, v. 24
Doi: http://doi.org/10.1161/01.STR.24.11.1667
Markus, HS., Ring, H., Kouris, K. and Costa, DC., 1993. Alterations in regional cerebral blood flow, with increased temporal interhemispheric asymmetries, in the normal elderly: an HMPAO SPECT study. Nucl Med Commun, v. 14
Doi: http://doi.org/10.1097/00006231-199308000-00002
1992
Markus, HS., Kouris, K., Costa, DC. and Ell, PJ., 1992. SPECT in epilepsy. Neurology, v. 42
Markus, HS. and Harrison, MJG., 1992. Response Stroke, v. 23
MARKUS, HS. and HARRISON, MJG., 1992. ESTIMATION OF CEREBROVASCULAR REACTIVITY USING TRANSCRANIAL DOPPLER, INCLUDING THE USE OF BREATH-HOLDING AS THE VASODILATORY STIMULUS STROKE, v. 23
Doi: http://doi.org/10.1161/01.STR.23.5.668
MARKUS, HS. and HARRISON, MJH., 1992. CARBON-DIOXIDE REACTIVITY OF CEREBRAL BLOOD-FLOW MEASURED BY TRANSCRANIAL SONOGRAPHY AS A DIAGNOSTIC CLUE TO INTRACRANIAL CAROTID STENOSIS IN THE PRESENCE OF NORMAL EXTRACRANIAL CEREBRAL-ARTERIES CEREBROVASCULAR DISEASES, v. 2
Doi: http://doi.org/10.1159/000109000
MARKUS, HS., DUCHEN, LW., PARKIN, EM., KURTZ, AB., JACOBS, HS., COSTA, DC. and HARRISON, MJ., 1992. CREUTZFELDT-JAKOB DISEASE IN RECIPIENTS OF HUMAN GROWTH-HORMONE IN THE UNITED-KINGDOM - A CLINICAL AND RADIOGRAPHIC STUDY QUARTERLY JOURNAL OF MEDICINE, v. 82
MARKUS, HS. and HOPKINSON, N., 1992. MIGRAINE AND HEADACHE IN SYSTEMIC LUPUS-ERYTHEMATOSUS AND THEIR RELATIONSHIP WITH ANTIBODIES AGAINST PHOSPHOLIPIDS JOURNAL OF NEUROLOGY, v. 239
Doi: http://doi.org/10.1007/BF00839210
MARKUS, HS., CHONG, EMF. and WILCOX, RG., 1992. GALLOPAMIL SLOW RELEASE - A DOUBLE-BLIND-STUDY OF TWICE DAILY VERSUS ONCE DAILY TREATMENT IN CHRONIC STABLE ANGINA EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, v. 42
HOWARD, LM. and MARKUS, H., 1992. PSEUDOOBSTRUCTION SECONDARY TO ANTICHOLINERGIC DRUGS IN PARKINSONS-DISEASE POSTGRADUATE MEDICAL JOURNAL, v. 68
Doi: http://doi.org/10.1136/pgmj.68.795.70
MARKUS, HS. and BOLAND, M., 1992. COGNITIVE ACTIVITY MONITORED BY NONINVASIVE MEASUREMENT OF CEREBRAL BLOOD-FLOW VELOCITY AND ITS APPLICATION TO THE INVESTIGATION OF CEREBRAL-DOMINANCE CORTEX, v. 28
Doi: http://doi.org/10.1016/S0010-9452(13)80228-6
ABBOTT, RA., COX, M., MARKUS, H. and TOMKINS, A., 1992. DIET, BODY SIZE AND MICRONUTRIENT STATUS IN PARKINSONS-DISEASE EUROPEAN JOURNAL OF CLINICAL NUTRITION, v. 46
MARKUS, H. and HARRISON, M., 1992. USE OF BREATH HOLDING FOR EVALUATING CEREBROVASCULAR RESERVE CAPACITY - REPLY STROKE, v. 23
MARKUS, HS., COX, M. and TOMKINS, AM., 1992. RAISED RESTING ENERGY-EXPENDITURE IN PARKINSONS-DISEASE AND ITS RELATIONSHIP TO MUSCLE RIGIDITY CLINICAL SCIENCE, v. 83
Doi: http://doi.org/10.1042/cs0830199
MARKUS, HS., BUNKER, CB., KOURIS, K., COSTA, DC. and HARRISON, MJ., 1992. RCBF ABNORMALITIES DETECTED, AND SEQUENTIALLY FOLLOWED, BY SPECT IN NEURO-BEHCETS SYNDROME WITH NORMAL CT AND MRI IMAGING JOURNAL OF NEUROLOGY, v. 239
1991
MARKUS, HS., 1991. A PROSPECTIVE FOLLOW-UP OF THUNDERCLAP HEADACHE MIMICKING SUBARACHNOID HEMORRHAGE JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, v. 54
Doi: http://doi.org/10.1136/jnnp.54.12.1117
MARKUS, H. and COWLEY, AJ., 1991. THE CENTRAL HEMODYNAMIC-EFFECTS OF A SINGLE INTRAVENOUS DOSE OF FLOSEQUINAN IN PATIENTS WITH SEVERE HEART-FAILURE EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, v. 40
1990
1989
MARKUS, HS., 1989. HEMATOGENOUS OSTEOMYELITIS IN THE ADULT - A CLINICAL AND EPIDEMIOLOGICAL-STUDY QUARTERLY JOURNAL OF MEDICINE, v. 71
MARKUS, HS., 1989. DIAGNOSTIC INVESTIGATIONS IN THE ELDERLY - THE CLINICAL USEFULNESS OF SERUM IRON AND TRANSFERRIN MEASUREMENTS IN THE DIAGNOSIS OF IRON-DEFICIENCY ANEMIA - AN AUDIT BRITISH JOURNAL OF CLINICAL PRACTICE, v. 43
1988
1986
